| Superfamily | Functional Family | Mutation Events | Mutation Types | DOPS | Incl. Bitscore | Incl. Evalue | Seqs |
|---|---|---|---|---|---|---|---|
| 2.60.40.150 | Phosphoinositide phospholipase C
2.60.40.150-FF-15221
|
6
|
SKCM (6)
|
89.5 | 154.5 | 1.8E-47 | 396 |
| 2.60.40.150 | Regulating synaptic membrane exocytosis 2
2.60.40.150-FF-15294
|
2
|
SKCM (2)
|
92.9 | 220.7 | 1.8E-67 | 1599 |
| 2.60.40.150 | X-linked retinitis pigmentosa GTPase regulator-interacting protein 1
2.60.40.150-FF-15398
|
6
|
UCEC (4)
COAD (2)
|
92.5 | 260.8 | 3.3E-80 | 95 |
| 1.10.10.10 | ETS-related transcription factor Elf-3
1.10.10.10-FF-262918
|
2
|
LIHC (2)
|
84.4 | 136.9 | 4.2E-42 | 250 |
| 1.10.10.10 | Transcription factor Dp-2, putative
1.10.10.10-FF-264734
|
2
|
UCEC (2)
|
86.9 | 127.9 | 3.1E-39 | 773 |
| 1.10.418.10 | Plastin-3 isoform 1
1.10.418.10-FF-4580
|
2
|
UCEC (2)
|
84.2 | 219.0 | 2.4E-67 | 417 |
| 1.10.418.10 | Alpha actinin, isoform G
1.10.418.10-FF-4604
|
16
|
LUSC (4)
STAD (2)
OV (2)
UCEC (8)
|
91.4 | 181.5 | 1.1E-55 | 825 |
| 1.10.418.10 | Filamin isoform A
1.10.418.10-FF-4618
|
8
|
STAD (2)
BLCA (2)
LGG (2)
LUSC (2)
|
84.6 | 211.0 | 7.0E-65 | 338 |
| 1.10.418.10 | Rattus norvegicus utrophin
1.10.418.10-FF-4640
|
4
|
LGG (2)
KIRP (2)
|
77.5 | 171.4 | 5.6E-53 | 188 |
| 1.10.418.10 | cDNA FLJ51929, highly similar to Plastin-3
1.10.418.10-FF-4762
|
4
|
UCEC (4)
|
77.3 | 110.8 | 2.1E-33 | 1226 |
| 3.30.230.70 | Exosome complex component RRP42
3.30.230.70-FF-5234
|
8
|
COAD (4)
LUAD (2)
LUSC (2)
|
85.6 | 418.8 | 5.4E-128 | 123 |
| 3.30.230.70 | Polyribonucleotide nucleotidyltransferase 1, mitochondrial
3.30.230.70-FF-5258
|
4
|
LUSC (2)
PAAD (2)
|
94.5 | 311.0 | 2.1E-93 | 3082 |
| 3.30.230.70 | Exosome complex component Rrp42
3.30.230.70-FF-5284
|
6
|
UCEC (4)
READ (2)
|
82.3 | 241.7 | 2.3E-73 | 1062 |
| 3.30.230.70 | Exosome complex component RRP43
3.30.230.70-FF-5287
|
6
|
UCEC (4)
BRCA (2)
|
90.1 | 356.0 | 6.3E-109 | 101 |
| 3.40.50.620 | Probable NH(3)-dependent NAD(+) synthetase
3.40.50.620-FF-89155
|
4
|
BRCA (2)
LUAD (2)
|
90.1 | 105.3 | 1.0E-30 | 4554 |
| 3.40.640.10 | Glycine dehydrogenase (decarboxylating), mitochondrial
3.40.640.10-FF-62877
|
2
|
COAD (2)
|
92.3 | 226.4 | 8.4E-68 | 2843 |
| 3.40.640.10 | Serine--pyruvate aminotransferase, mitochondrial
3.40.640.10-FF-62953
|
4
|
SKCM (4)
|
92.1 | 249.3 | 1.1E-75 | 1160 |
| 3.40.640.10 | 5-aminolevulinate synthase, erythroid-specific, mitochondrial
3.40.640.10-FF-63070
|
2
|
UCEC (2)
|
96.2 | 270.4 | 7.6E-82 | 1313 |
| 3.40.640.10 | Kynureninase (L-kynurenine hydrolase) variant
3.40.640.10-FF-63117
|
14
|
SKCM (8)
UCEC (4)
GBM (2)
|
91.6 | 300.6 | 3.7E-91 | 1141 |
| 2.30.30.140 | Lethal(3)malignant brain tumor-like protein 2
2.30.30.140-FF-3041
|
10
|
UCEC (4)
SKCM (4)
PAAD (2)
|
84.4 | 153.0 | 2.9E-47 | 305 |