| Superfamily | Functional Family | Mutation Events | Mutation Types | DOPS | Incl. Bitscore | Incl. Evalue | Seqs |
|---|---|---|---|---|---|---|---|
| 1.10.150.60 | Lysine-specific demethylase 5B
1.10.150.60-FF-743
|
8
|
BLCA (2)
BRCA (2)
READ (2)
HNSC (2)
|
70.9 | 187.2 | 2.8E-58 | 111 |
| 1.10.287.40 | Serine--tRNA ligase, mitochondrial
1.10.287.40-FF-2483
|
4
|
SKCM (2)
UCEC (2)
|
77.3 | 164.6 | 1.3E-51 | 34 |
| 1.10.150.80 | Werner syndrome ATP-dependent helicase
1.10.150.80-FF-3214
|
2
|
LUAD (2)
|
75.2 | 146.8 | 3.5E-46 | 45 |
| 1.10.418.10 | cDNA FLJ51929, highly similar to Plastin-3
1.10.418.10-FF-4762
|
4
|
UCEC (4)
|
77.3 | 110.8 | 2.1E-33 | 1226 |
| 1.10.418.10 | Plastin-3 isoform 1
1.10.418.10-FF-4580
|
2
|
UCEC (2)
|
84.2 | 219.0 | 2.4E-67 | 417 |
| 1.10.418.10 | Alpha actinin, isoform G
1.10.418.10-FF-4604
|
16
|
LUSC (4)
STAD (2)
OV (2)
UCEC (8)
|
91.4 | 181.5 | 1.1E-55 | 825 |
| 1.10.418.10 | Plastin-3 isoform 1
1.10.418.10-FF-4790
|
8
|
SKCM (2)
LUSC (2)
HNSC (2)
ACC (2)
|
88.2 | 104.2 | 2.5E-31 | 1207 |
| 3.10.620.10 | Protein N-terminal glutamine amidohydrolase
3.10.620.10-FF-71
|
2
|
CESC (2)
|
83.0 | 357.4 | 4.4E-110 | 52 |
| 1.10.418.10 | Filamin isoform A
1.10.418.10-FF-4618
|
8
|
STAD (2)
BLCA (2)
LGG (2)
LUSC (2)
|
84.6 | 211.0 | 7.0E-65 | 338 |
| 1.10.418.10 | Rattus norvegicus utrophin
1.10.418.10-FF-4640
|
4
|
LGG (2)
KIRP (2)
|
77.5 | 171.4 | 5.6E-53 | 188 |
| 3.30.1520.10 | Sorting nexin 10
3.30.1520.10-FF-3957
|
2
|
LUAD (2)
|
86.3 | 188.0 | 7.2E-58 | 277 |
| 3.30.1520.10 | Sorting nexin 9 variant
3.30.1520.10-FF-3967
|
6
|
UCEC (4)
LUAD (2)
|
78.9 | 208.6 | 1.8E-64 | 193 |
| 3.30.1520.10 | Sorting nexin-24
3.30.1520.10-FF-4053
|
4
|
SKCM (2)
UCEC (2)
|
91.9 | 100.5 | 3.8E-31 | 194 |
| 3.30.1520.10 | Neutrophil cytosol factor 1
3.30.1520.10-FF-3906
|
2
|
STAD (2)
|
76.7 | 176.9 | 8.3E-55 | 65 |
| 3.30.230.70 | Exosome complex component RRP42
3.30.230.70-FF-5234
|
8
|
COAD (4)
LUAD (2)
LUSC (2)
|
85.6 | 418.8 | 5.4E-128 | 123 |
| 3.30.230.70 | Polyribonucleotide nucleotidyltransferase 1, mitochondrial
3.30.230.70-FF-5258
|
4
|
LUSC (2)
PAAD (2)
|
94.5 | 311.0 | 2.1E-93 | 3082 |
| 3.40.640.10 | Glycine dehydrogenase (decarboxylating), mitochondrial
3.40.640.10-FF-62877
|
2
|
COAD (2)
|
92.3 | 226.4 | 8.4E-68 | 2843 |
| 3.30.230.70 | Exosome complex component Rrp42
3.30.230.70-FF-5284
|
6
|
UCEC (4)
READ (2)
|
82.3 | 241.7 | 2.3E-73 | 1062 |
| 3.30.230.70 | Exosome complex component RRP43
3.30.230.70-FF-5287
|
6
|
UCEC (4)
BRCA (2)
|
90.1 | 356.0 | 6.3E-109 | 101 |
| 3.40.366.10 | Putative animal-type fatty acid synthase
3.40.366.10-FF-12366
|
4
|
UCEC (2)
COAD (2)
|
86.0 | 200.2 | 2.5E-61 | 110 |