| Superfamily | Functional Family | Mutation Events | Mutation Types | DOPS | Incl. Bitscore | Incl. Evalue | Seqs |
|---|---|---|---|---|---|---|---|
| 2.60.200.20 | E3 ubiquitin-protein ligase RNF8
2.60.200.20-FF-8161
|
4
|
LGG (2)
BLCA (2)
|
88.8 | 156.0 | 2.4E-48 | 106 |
| 2.60.200.20 | Kinesin-like protein unc-104
2.60.200.20-FF-8178
|
8
|
LUAD (2)
UCEC (4)
SKCM (2)
|
82.6 | 131.5 | 5.0E-40 | 854 |
| 3.30.450.40 | Rod cGMP-specific 3',5'-cyclic phosphodiesterase alpha-subunit
3.30.450.40-FF-30324
|
2
|
SKCM (2)
|
94.7 | 261.2 | 4.3E-80 | 269 |
| 3.40.449.10 | Phosphoenolpyruvate carboxykinase [GTP], mitochondrial
3.40.449.10-FF-1486
|
16
|
BLCA (2)
COAD (2)
SKCM (12)
|
93.9 | 197.7 | 1.3E-59 | 1951 |
| 3.60.20.10 | Proteasome subunit beta type
3.60.20.10-FF-15794
|
2
|
LUSC (2)
|
90.6 | 271.7 | 5.8E-83 | 500 |
| 3.60.20.10 | Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1
3.60.20.10-FF-15819
|
8
|
STAD (2)
GBM (2)
UCEC (4)
|
88.7 | 197.4 | 8.8E-59 | 1971 |
| 3.90.1110.10 | RNA polymerase II subunit
3.90.1110.10-FF-1871
|
4
|
DLBC (2)
UCEC (2)
|
89.9 | 220.3 | 6.6E-67 | 1605 |
| 3.90.1110.10 | DNA-directed RNA polymerase
3.90.1110.10-FF-1889
|
16
|
UCEC (8)
COAD (2)
LUAD (2)
BRCA (2)
UCS (2)
|
92.0 | 193.7 | 5.5E-59 | 855 |
| 2.30.130.10 | 60S ribosome subunit biogenesis protein
2.30.130.10-FF-4587
|
2
|
UCEC (2)
|
96.0 | 139.8 | 4.6E-43 | 1079 |
| 3.40.50.880 | Probable gamma-glutamyl hydrolase 3
3.40.50.880-FF-33669
|
8
|
CESC (2)
LUAD (2)
LUSC (4)
|
91.3 | 302.4 | 3.8E-92 | 309 |
| 3.90.470.10 | 39S ribosomal protein L22, mitochondrial
3.90.470.10-FF-1953
|
6
|
UCEC (4)
CESC (2)
|
85.9 | 240.6 | 4.3E-74 | 112 |
| 2.40.128.20 | Beta-lactoglobulin I
2.40.128.20-FF-5792
|
4
|
UCEC (2)
BRCA (2)
|
90.9 | 192.4 | 1.2E-59 | 53 |
| 2.40.128.20 | Complement component C8 gamma chain
2.40.128.20-FF-5910
|
2
|
CESC (2)
|
95.4 | 162.9 | 1.2E-50 | 41 |
| 2.60.40.150 | Synaptotagmin 1, isoform I
2.60.40.150-FF-15108
|
2
|
UCEC (2)
|
89.9 | 206.1 | 4.2E-63 | 775 |
| 2.60.40.150 | Phosphoinositide phospholipase C
2.60.40.150-FF-15154
|
2
|
SKCM (2)
|
73.1 | 276.3 | 2.2E-85 | 62 |
| 3.20.20.210 | Uroporphyrinogen decarboxylase
3.20.20.210-FF-2320
|
4
|
UCEC (4)
|
83.4 | 217.6 | 1.6E-66 | 184 |
| 3.20.200.10 | Elongation factor 2 kinase
3.20.200.10-FF-309
|
2
|
UCEC (2)
|
84.0 | 139.3 | 4.5E-43 | 316 |
| 3.40.1110.10 | Copper-transporting ATPase 1
3.40.1110.10-FF-15453
|
8
|
LUAD (2)
STAD (4)
CESC (2)
|
76.5 | 214.4 | 2.4E-66 | 97 |
| 1.10.10.10 | Segment polarity protein dishevelled
1.10.10.10-FF-263989
|
6
|
LUAD (4)
UCEC (2)
|
90.2 | 133.5 | 3.8E-41 | 590 |
| 1.10.10.10 | ETS translocation variant 1
1.10.10.10-FF-264144
|
14
|
LUAD (2)
SKCM (4)
UCEC (6)
COAD (2)
|
88.4 | 106.2 | 6.1E-32 | 1039 |