Functional Families
Browse Information on Functional Families (FunFams) in CATH
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Showing 121 to 140 of 884 entries
Superfamily Functional Family Mutation Events Mutation Types DOPS Incl. Bitscore Incl. Evalue Seqs
2.60.40.150 Synaptotagmin 1, isoform I
2.60.40.150-FF-15108
2
UCEC (2)
89.9 206.1 4.2E-63 775
2.60.40.150 Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
2.60.40.150-FF-15597
108
BLCA (4)
BRCA (38)
SARC (2)
STAD (16)
UCEC (18)
GBM (2)
TGCT (2)
HNSC (6)
COAD (8)
LGG (4)
LUAD (2)
PRAD (2)
UCS (2)
CESC (2)
87.7 115.0 1.6E-35 229
2.60.40.150 Phosphoinositide phospholipase C
2.60.40.150-FF-15154
2
SKCM (2)
73.1 276.3 2.2E-85 62
2.60.40.150 Regulating synaptic membrane exocytosis 2
2.60.40.150-FF-15294
2
SKCM (2)
92.9 220.7 1.8E-67 1599
2.60.40.150 X-linked retinitis pigmentosa GTPase regulator-interacting protein 1
2.60.40.150-FF-15398
6
UCEC (4)
COAD (2)
92.5 260.8 3.3E-80 95
3.40.1110.10 Copper-transporting ATPase 1
3.40.1110.10-FF-15453
8
LUAD (2)
STAD (4)
CESC (2)
76.5 214.4 2.4E-66 97
3.20.20.210 Uroporphyrinogen decarboxylase
3.20.20.210-FF-2320
4
UCEC (4)
83.4 217.6 1.6E-66 184
3.20.200.10 Elongation factor 2 kinase
3.20.200.10-FF-309
2
UCEC (2)
84.0 139.3 4.5E-43 316
3.30.870.10 Mitochondrial cardiolipin hydrolase
3.30.870.10-FF-12790
14
STAD (2)
DLBC (2)
BLCA (2)
KIRP (2)
CESC (2)
UCEC (4)
93.2 232.1 9.3E-72 52
3.30.870.10 Tyrosyl-DNA phosphodiesterase 1
3.30.870.10-FF-12826
2
LUSC (2)
91.6 171.5 1.1E-52 174
1.10.10.10 DEP domain-containing protein 1A
1.10.10.10-FF-263040
2
HNSC (2)
93.4 151.6 1.8E-47 201
1.10.10.10 Anaphase-promoting complex subunit 2
1.10.10.10-FF-159555
4
BLCA (4)
70.8 150.6 4.6E-47 76
1.10.10.10 Transcription factor Dp-2, putative
1.10.10.10-FF-264734
2
UCEC (2)
86.9 127.9 3.1E-39 773
1.10.10.10 ETS-related transcription factor Elf-3
1.10.10.10-FF-262918
2
LIHC (2)
84.4 136.9 4.2E-42 250
1.10.10.10 Segment polarity protein dishevelled
1.10.10.10-FF-263989
6
LUAD (4)
UCEC (2)
90.2 133.5 3.8E-41 590
1.10.10.10 ETS translocation variant 1
1.10.10.10-FF-264144
14
LUAD (2)
SKCM (4)
UCEC (6)
COAD (2)
88.4 106.2 6.1E-32 1039
1.10.10.10 cDNA FLJ58509, highly similar to Cullin-1
1.10.10.10-FF-264801
6
UCEC (2)
STAD (2)
LUAD (2)
88.9 133.0 3.4E-41 363
1.10.150.60 Lysine-specific demethylase 5B
1.10.150.60-FF-743
8
BLCA (2)
BRCA (2)
READ (2)
HNSC (2)
70.9 187.2 2.8E-58 111
1.10.10.10 La ribonucleoprotein domain family, member 4
1.10.10.10-FF-264835
2
BLCA (2)
97.8 125.6 9.9E-39 367
1.10.10.10 Putative histone H1.6
1.10.10.10-FF-265163
4
CESC (2)
UCEC (2)
84.2 114.1 1.6E-35 158