| Superfamily | Functional Family | Mutation Events | Mutation Types | DOPS | Incl. Bitscore | Incl. Evalue | Seqs |
|---|---|---|---|---|---|---|---|
| 2.60.40.150 | Phosphoinositide phospholipase C
2.60.40.150-FF-15221
|
6
|
SKCM (6)
|
89.5 | 154.5 | 1.8E-47 | 396 |
| 2.60.40.150 | Regulating synaptic membrane exocytosis 2
2.60.40.150-FF-15294
|
2
|
SKCM (2)
|
92.9 | 220.7 | 1.8E-67 | 1599 |
| 1.10.10.10 | Anaphase-promoting complex subunit 2
1.10.10.10-FF-159555
|
4
|
BLCA (4)
|
70.8 | 150.6 | 4.6E-47 | 76 |
| 2.60.40.150 | X-linked retinitis pigmentosa GTPase regulator-interacting protein 1
2.60.40.150-FF-15398
|
6
|
UCEC (4)
COAD (2)
|
92.5 | 260.8 | 3.3E-80 | 95 |
| 3.20.20.210 | Uroporphyrinogen decarboxylase
3.20.20.210-FF-2320
|
4
|
UCEC (4)
|
83.4 | 217.6 | 1.6E-66 | 184 |
| 3.20.200.10 | Elongation factor 2 kinase
3.20.200.10-FF-309
|
2
|
UCEC (2)
|
84.0 | 139.3 | 4.5E-43 | 316 |
| 3.40.1110.10 | Copper-transporting ATPase 1
3.40.1110.10-FF-15453
|
8
|
LUAD (2)
STAD (4)
CESC (2)
|
76.5 | 214.4 | 2.4E-66 | 97 |
| 2.60.40.150 | Small nuclear ribonucleoprotein 200kDa
2.60.40.150-FF-15495
|
2
|
UCEC (2)
|
88.7 | 133.5 | 3.9E-41 | 388 |
| 2.60.40.150 | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
2.60.40.150-FF-15597
|
108
|
BLCA (4)
BRCA (38)
SARC (2)
STAD (16)
UCEC (18)
GBM (2)
TGCT (2)
HNSC (6)
COAD (8)
LGG (4)
LUAD (2)
PRAD (2)
UCS (2)
CESC (2)
|
87.7 | 115.0 | 1.6E-35 | 229 |
| 3.30.870.10 | Mitochondrial cardiolipin hydrolase
3.30.870.10-FF-12790
|
14
|
STAD (2)
DLBC (2)
BLCA (2)
KIRP (2)
CESC (2)
UCEC (4)
|
93.2 | 232.1 | 9.3E-72 | 52 |
| 3.30.870.10 | Tyrosyl-DNA phosphodiesterase 1
3.30.870.10-FF-12826
|
2
|
LUSC (2)
|
91.6 | 171.5 | 1.1E-52 | 174 |
| 1.10.10.10 | DEP domain-containing protein 1A
1.10.10.10-FF-263040
|
2
|
HNSC (2)
|
93.4 | 151.6 | 1.8E-47 | 201 |
| 1.10.10.10 | Transcription factor Dp-2, putative
1.10.10.10-FF-264734
|
2
|
UCEC (2)
|
86.9 | 127.9 | 3.1E-39 | 773 |
| 1.10.10.10 | Segment polarity protein dishevelled
1.10.10.10-FF-263989
|
6
|
LUAD (4)
UCEC (2)
|
90.2 | 133.5 | 3.8E-41 | 590 |
| 1.10.10.10 | ETS translocation variant 1
1.10.10.10-FF-264144
|
14
|
LUAD (2)
SKCM (4)
UCEC (6)
COAD (2)
|
88.4 | 106.2 | 6.1E-32 | 1039 |
| 1.10.10.10 | ETS-related transcription factor Elf-3
1.10.10.10-FF-262918
|
2
|
LIHC (2)
|
84.4 | 136.9 | 4.2E-42 | 250 |
| 1.10.418.10 | cDNA FLJ51929, highly similar to Plastin-3
1.10.418.10-FF-4762
|
4
|
UCEC (4)
|
77.3 | 110.8 | 2.1E-33 | 1226 |
| 1.10.10.10 | cDNA FLJ58509, highly similar to Cullin-1
1.10.10.10-FF-264801
|
6
|
UCEC (2)
STAD (2)
LUAD (2)
|
88.9 | 133.0 | 3.4E-41 | 363 |
| 1.10.10.10 | La ribonucleoprotein domain family, member 4
1.10.10.10-FF-264835
|
2
|
BLCA (2)
|
97.8 | 125.6 | 9.9E-39 | 367 |
| 1.10.287.40 | Serine--tRNA ligase, mitochondrial
1.10.287.40-FF-2483
|
4
|
SKCM (2)
UCEC (2)
|
77.3 | 164.6 | 1.3E-51 | 34 |