| Superfamily | Functional Family | Mutation Events | Mutation Types | DOPS | Incl. Bitscore | Incl. Evalue | Seqs |
|---|---|---|---|---|---|---|---|
| 2.30.29.30 | RAC-beta serine/threonine-protein kinase A
2.30.29.30-FF-22238
|
120
|
BRCA (48)
THCA (10)
CESC (8)
LUAD (4)
PRAD (4)
STAD (2)
UCEC (16)
COAD (12)
SKCM (6)
LUSC (6)
BLCA (2)
HNSC (2)
|
91.7 | 162.8 | 3.8E-50 | 1420 |
| 2.30.29.30 | Unconventional myosin-X
2.30.29.30-FF-22254
|
6
|
LUAD (2)
LUSC (4)
|
71.3 | 132.1 | 3.0E-42 | 200 |
| 2.30.29.30 | Disabled homolog 1 (Drosophila)
2.30.29.30-FF-22263
|
2
|
SKCM (2)
|
86.0 | 218.1 | 6.6E-67 | 373 |
| 2.30.29.30 | Guanine nucleotide exchange factor
2.30.29.30-FF-22277
|
10
|
CESC (2)
STAD (2)
SARC (2)
HNSC (2)
SKCM (2)
|
87.1 | 145.5 | 1.7E-44 | 517 |
| 2.30.29.30 | cDNA FLJ53435, highly similar to Ezrin
2.30.29.30-FF-22306
|
10
|
UCEC (6)
LGG (2)
READ (2)
|
97.6 | 153.9 | 3.1E-47 | 1358 |
| 2.30.29.30 | APBB2 protein
2.30.29.30-FF-22332
|
4
|
LIHC (2)
CHOL (2)
|
76.7 | 207.8 | 4.4E-64 | 185 |
| 2.30.29.30 | IQ motif and SEC7 domain-containing protein 1
2.30.29.30-FF-22362
|
8
|
STAD (2)
COAD (2)
BLCA (4)
|
89.6 | 190.2 | 3.2E-58 | 491 |
| 2.30.29.30 | TBC1 domain family member 2A
2.30.29.30-FF-22381
|
6
|
BLCA (2)
STAD (2)
COAD (2)
|
88.3 | 121.1 | 1.3E-37 | 116 |
| 2.30.29.30 | Docking protein 1 variant
2.30.29.30-FF-22459
|
2
|
UCEC (2)
|
90.6 | 146.6 | 1.7E-45 | 179 |
| 3.10.580.10 | Cystathionine beta-synthase
3.10.580.10-FF-15836
|
4
|
UCEC (4)
|
72.1 | 269.1 | 5.3E-83 | 107 |
| 1.10.1420.10 | Mismatch repair protein Msh2
1.10.1420.10-FF-4746
|
6
|
LUAD (2)
COAD (2)
READ (2)
|
80.2 | 239.4 | 1.5E-73 | 82 |
| 3.30.1780.10 | Ketimine reductase mu-crystallin
3.30.1780.10-FF-1447
|
10
|
COAD (2)
STAD (2)
BLCA (4)
CESC (2)
|
88.8 | 155.1 | 2.1E-48 | 63 |
| 3.40.50.720 | NEDD8-activating enzyme E1 regulatory subunit
3.40.50.720-FF-287593
|
2
|
UCEC (2)
|
91.6 | 116.8 | 5.9E-36 | 513 |
| 4.10.900.10 | Transcription factor 7-like 2
4.10.900.10-FF-590
|
4
|
UCEC (2)
STAD (2)
|
77.1 | 106.8 | 2.9E-33 | 165 |
| 2.60.40.640 | Arrestin 1, isoform C
2.60.40.640-FF-1876
|
8
|
SKCM (4)
UCEC (2)
BLCA (2)
|
82.8 | 192.9 | 1.6E-58 | 883 |
| 1.10.150.50 | HCG1741805, isoform CRA_a
1.10.150.50-FF-4747
|
4
|
SKCM (2)
LUSC (2)
|
78.9 | 124.7 | 5.6E-39 | 75 |
| 1.10.150.50 | Receptor protein-tyrosine kinase
1.10.150.50-FF-4790
|
6
|
LUAD (2)
COAD (2)
UCEC (2)
|
77.1 | 141.5 | 3.9E-44 | 102 |
| 3.40.140.10 | Probable deoxycytidylate deaminase
3.40.140.10-FF-13424
|
2
|
COAD (2)
|
92.2 | 209.0 | 4.7E-64 | 697 |
| 3.40.50.670 | Probable DNA topoisomerase 2
3.40.50.670-FF-2841
|
22
|
STAD (4)
COAD (12)
UCEC (4)
PAAD (2)
|
80.2 | 203.0 | 4.1E-63 | 1062 |
| 3.90.550.10 | Putative n-acylneuraminate cytidylyltransferase
3.90.550.10-FF-64185
|
14
|
UCEC (6)
COAD (4)
SKCM (2)
BLCA (2)
|
82.3 | 381.4 | 5.2E-117 | 91 |