| Superfamily | Functional Family | Mutation Events | Mutation Types | DOPS | Incl. Bitscore | Incl. Evalue | Seqs |
|---|---|---|---|---|---|---|---|
| 2.40.70.10 | Beta-site APP-cleaving enzyme 1
2.40.70.10-FF-22859
|
4
|
UCEC (4)
|
78.5 | 202.4 | 9.6E-63 | 98 |
| 2.40.70.10 | Cathepsin D (A01 family)
2.40.70.10-FF-23002
|
6
|
GBM (2)
UCEC (2)
LUAD (2)
|
87.2 | 142.9 | 9.0E-44 | 362 |
| 2.60.40.150 | Small nuclear ribonucleoprotein 200kDa
2.60.40.150-FF-15495
|
2
|
UCEC (2)
|
88.7 | 133.5 | 3.9E-41 | 388 |
| 2.60.40.150 | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
2.60.40.150-FF-15597
|
108
|
BLCA (4)
BRCA (38)
SARC (2)
STAD (16)
UCEC (18)
GBM (2)
TGCT (2)
HNSC (6)
COAD (8)
LGG (4)
LUAD (2)
PRAD (2)
UCS (2)
CESC (2)
|
87.7 | 115.0 | 1.6E-35 | 229 |
| 1.10.10.10 | Anaphase-promoting complex subunit 2
1.10.10.10-FF-159555
|
4
|
BLCA (4)
|
70.8 | 150.6 | 4.6E-47 | 76 |
| 1.10.10.10 | ETS-related transcription factor Elf-3
1.10.10.10-FF-262918
|
2
|
LIHC (2)
|
84.4 | 136.9 | 4.2E-42 | 250 |
| 1.10.10.10 | cDNA FLJ58509, highly similar to Cullin-1
1.10.10.10-FF-264801
|
6
|
UCEC (2)
STAD (2)
LUAD (2)
|
88.9 | 133.0 | 3.4E-41 | 363 |
| 1.10.10.10 | La ribonucleoprotein domain family, member 4
1.10.10.10-FF-264835
|
2
|
BLCA (2)
|
97.8 | 125.6 | 9.9E-39 | 367 |
| 1.10.287.40 | Serine--tRNA ligase, mitochondrial
1.10.287.40-FF-2483
|
4
|
SKCM (2)
UCEC (2)
|
77.3 | 164.6 | 1.3E-51 | 34 |
| 3.10.620.10 | Protein N-terminal glutamine amidohydrolase
3.10.620.10-FF-71
|
2
|
CESC (2)
|
83.0 | 357.4 | 4.4E-110 | 52 |
| 3.30.1520.10 | Sorting nexin 10
3.30.1520.10-FF-3957
|
2
|
LUAD (2)
|
86.3 | 188.0 | 7.2E-58 | 277 |
| 3.30.1520.10 | Sorting nexin 9 variant
3.30.1520.10-FF-3967
|
6
|
UCEC (4)
LUAD (2)
|
78.9 | 208.6 | 1.8E-64 | 193 |
| 3.30.1520.10 | Sorting nexin-24
3.30.1520.10-FF-4053
|
4
|
SKCM (2)
UCEC (2)
|
91.9 | 100.5 | 3.8E-31 | 194 |
| 3.90.530.10 | DNA repair protein-complementing XP-A cells
3.90.530.10-FF-202
|
4
|
UCEC (4)
|
82.7 | 168.9 | 1.6E-52 | 145 |
| 2.120.10.80 | Kelch-like protein 12
2.120.10.80-FF-8779
|
16
|
SKCM (4)
UCEC (4)
STAD (4)
COAD (2)
HNSC (2)
|
71.5 | 325.6 | 2.2E-101 | 124 |
| 2.30.30.140 | Survival motor neuron protein
2.30.30.140-FF-4819
|
2
|
UCEC (2)
|
91.8 | 104.2 | 9.5E-33 | 550 |
| 2.30.30.40 | Dynamin-binding protein
2.30.30.40-FF-19043
|
2
|
LUSC (2)
|
70.9 | 175.3 | 7.8E-55 | 88 |
| 3.30.428.10 | Uncharacterised protein
3.30.428.10-FF-6697
|
14
|
BLCA (6)
GBM (2)
LUSC (2)
UCEC (4)
|
83.8 | 209.7 | 3.7E-65 | 41 |
| 3.30.428.10 | Aprataxin
3.30.428.10-FF-6749
|
8
|
UCEC (2)
BLCA (2)
READ (2)
GBM (2)
|
82.6 | 209.4 | 7.4E-66 | 109 |
| 3.90.1300.10 | Glutamyl-tRNA(Gln) amidotransferase subunit A
3.90.1300.10-FF-7657
|
14
|
COAD (8)
UCEC (4)
BLCA (2)
|
95.2 | 308.4 | 1.8E-92 | 1421 |