| Superfamily | Functional Family | Mutation Events | Mutation Types | DOPS | Incl. Bitscore | Incl. Evalue | Seqs |
|---|---|---|---|---|---|---|---|
| 3.40.50.1820 | Lysosomal Pro-X carboxypeptidase, putative
3.40.50.1820-FF-115164
|
14
|
ESCA (2)
UCEC (6)
SKCM (2)
LUSC (4)
|
92.3 | 386.8 | 4.6E-118 | 232 |
| 3.30.70.680 | TNFRSF1A-associated via death domain
3.30.70.680-FF-53
|
4
|
PAAD (2)
UCEC (2)
|
93.8 | 208.3 | 1.5E-64 | 52 |
| 3.40.50.1480 | Putative adenosylhomocysteinase 3
3.40.50.1480-FF-2846
|
4
|
UCEC (2)
GBM (2)
|
90.9 | 110.5 | 1.6E-33 | 1417 |
| 3.40.50.1820 | Bifunctional epoxide hydrolase 2
3.40.50.1820-FF-115289
|
6
|
STAD (2)
UCEC (2)
LUSC (2)
|
90.3 | 233.5 | 2.1E-70 | 1152 |
| 3.40.50.1820 | Protease II (Oligopeptidase B)
3.40.50.1820-FF-115346
|
4
|
UCEC (4)
|
94.5 | 238.9 | 1.6E-71 | 3034 |
| 3.40.50.1820 | Putative animal-type fatty acid synthase
3.40.50.1820-FF-115364
|
2
|
UCEC (2)
|
83.4 | 193.1 | 1.4E-59 | 111 |
| 3.90.1180.10 | 50S ribosomal protein L13
3.90.1180.10-FF-2128
|
4
|
LUAD (2)
SKCM (2)
|
92.2 | 110.4 | 1.1E-32 | 3224 |
| 3.40.50.2300 | Metabotropic glutamate receptor 5
3.40.50.2300-FF-6367
|
18
|
SARC (2)
MESO (2)
COAD (2)
LUAD (2)
SKCM (4)
STAD (2)
UCEC (2)
PAAD (2)
|
85.5 | 228.1 | 3.6E-70 | 189 |
| 3.40.50.2300 | Gamma-aminobutyric acid B receptor
3.40.50.2300-FF-150792
|
2
|
GBM (2)
|
75.9 | 346.9 | 5.4E-107 | 68 |
| 1.10.10.430 | Protein phosphatase 1A isoform 1
1.10.10.430-FF-10
|
8
|
COAD (2)
STAD (2)
SKCM (2)
LGG (2)
|
71.0 | 130.1 | 8.1E-41 | 409 |
| 3.90.850.10 | Probable fumarylacetoacetase (Fumarylacetoacetate hydrolase) protein
3.90.850.10-FF-5343
|
2
|
BLCA (2)
|
82.8 | 417.2 | 1.5E-126 | 1580 |
| 1.10.506.10 | Plexin-B2
1.10.506.10-FF-1279
|
12
|
STAD (2)
UCEC (2)
COAD (2)
LUAD (2)
READ (2)
BLCA (2)
|
82.3 | 553.7 | 1.1E-170 | 127 |
| 1.10.506.10 | Neurofibromin 1, isoform B
1.10.506.10-FF-1331
|
4
|
HNSC (2)
UCEC (2)
|
90.7 | 179.8 | 4.3E-55 | 271 |
| 2.60.200.20 | Centrosomal protein of 170 kDa
2.60.200.20-FF-8129
|
8
|
STAD (2)
UCEC (4)
READ (2)
|
77.1 | 156.1 | 4.3E-48 | 256 |
| 2.60.200.20 | E3 ubiquitin-protein ligase CHFR
2.60.200.20-FF-8114
|
6
|
LUAD (2)
BLCA (2)
KIRC (2)
|
82.1 | 175.9 | 8.4E-55 | 68 |
| 2.60.200.20 | E3 ubiquitin-protein ligase RNF8
2.60.200.20-FF-8161
|
4
|
LGG (2)
BLCA (2)
|
88.8 | 156.0 | 2.4E-48 | 106 |
| 2.60.200.20 | Mediator of DNA damage checkpoint protein 1
2.60.200.20-FF-8126
|
2
|
UCEC (2)
|
77.1 | 183.9 | 2.4E-57 | 47 |
| 2.60.200.20 | Kinesin-like protein unc-104
2.60.200.20-FF-8178
|
8
|
LUAD (2)
UCEC (4)
SKCM (2)
|
82.6 | 131.5 | 5.0E-40 | 854 |
| 3.30.450.40 | Rod cGMP-specific 3',5'-cyclic phosphodiesterase alpha-subunit
3.30.450.40-FF-30324
|
2
|
SKCM (2)
|
94.7 | 261.2 | 4.3E-80 | 269 |
| 3.40.449.10 | Phosphoenolpyruvate carboxykinase [GTP], mitochondrial
3.40.449.10-FF-1486
|
16
|
BLCA (2)
COAD (2)
SKCM (12)
|
93.9 | 197.7 | 1.3E-59 | 1951 |