| Superfamily | Functional Family | Mutation Events | Mutation Types | DOPS | Incl. Bitscore | Incl. Evalue | Seqs |
|---|---|---|---|---|---|---|---|
| 3.40.440.10 | Adenylosuccinate synthetase 1, chloroplastic
3.40.440.10-FF-3574
|
10
|
LUAD (4)
COAD (2)
READ (2)
STAD (2)
|
82.9 | 122.5 | 6.0E-39 | 3938 |
| 1.10.790.10 | Major prion protein
1.10.790.10-FF-74
|
2
|
UCEC (2)
|
89.0 | 123.8 | 2.7E-39 | 822 |
| 1.20.58.60 | Spectrin alpha chain, brain
1.20.58.60-FF-16025
|
2
|
SKCM (2)
|
72.1 | 157.5 | 6.6E-49 | 160 |
| 1.25.40.180 | Programmed cell death protein 4
1.25.40.180-FF-4276
|
2
|
UCS (2)
|
71.4 | 249.5 | 4.5E-77 | 91 |
| 1.25.40.180 | Nuclear cap-binding protein subunit 1
1.25.40.180-FF-4407
|
2
|
CESC (2)
|
87.3 | 164.8 | 4.5E-51 | 353 |
| 2.10.70.10 | Complement receptor type 1
2.10.70.10-FF-16845
|
2
|
COAD (2)
|
71.8 | 127.4 | 6.3E-40 | 36 |
| 2.10.70.10 | Platelet complement factor H
2.10.70.10-FF-16894
|
8
|
SKCM (8)
|
91.8 | 107.5 | 1.1E-33 | 65 |
| 2.10.70.10 | Complement C2 isoform 1
2.10.70.10-FF-16924
|
8
|
SKCM (6)
LUSC (2)
|
80.8 | 104.9 | 9.5E-33 | 88 |
| 2.10.70.10 | Membrane cofactor protein
2.10.70.10-FF-16929
|
4
|
UCEC (2)
LGG (2)
|
72.8 | 112.2 | 1.7E-35 | 28 |
| 2.10.70.10 | Complement decay-accelerating factor, GPI-anchored
2.10.70.10-FF-16956
|
2
|
UCEC (2)
|
75.5 | 119.6 | 1.2E-37 | 45 |
| 2.10.70.10 | Complement factor H-related 1
2.10.70.10-FF-17148
|
2
|
SKCM (2)
|
90.1 | 101.2 | 1.0E-31 | 82 |
| 2.40.33.10 | Pyruvate kinase PKM
2.40.33.10-FF-1967
|
4
|
LUSC (2)
SKCM (2)
|
79.4 | 183.3 | 2.6E-57 | 181 |
| 2.60.120.10 | Rap guanine nucleotide exchange factor 4
2.60.120.10-FF-16193
|
2
|
STAD (2)
|
80.6 | 251.5 | 2.0E-77 | 332 |
| 2.60.40.10 | Polycystic kidney disease-associated protein
2.60.40.10-FF-7523
|
10
|
UCEC (4)
COAD (2)
LUSC (2)
STAD (2)
|
82.0 | 149.4 | 4.4E-47 | 34 |
| 2.60.40.10 | Inositol polyphosphate 5-phosphatase OCRL-1
2.60.40.10-FF-11465
|
2
|
BRCA (2)
|
90.2 | 154.7 | 1.3E-47 | 218 |
| 2.60.40.10 | Transcription factor COE1, putative
2.60.40.10-FF-79153
|
16
|
BLCA (2)
LUSC (2)
HNSC (2)
LUAD (2)
COAD (2)
UCEC (2)
READ (2)
ESCA (2)
|
81.3 | 144.6 | 1.4E-44 | 1153 |
| 2.60.40.10 | Cytotoxic T-lymphocyte protein 4
2.60.40.10-FF-131974
|
2
|
SARC (2)
|
79.2 | 224.0 | 1.2E-69 | 72 |
| 2.60.40.10 | MHC class II antigen
2.60.40.10-FF-132542
|
4
|
CESC (2)
UCEC (2)
|
83.4 | 176.3 | 7.1E-55 | 136 |
| 2.60.40.10 | C-kit receptor tyrosine kinase
2.60.40.10-FF-132947
|
2
|
HNSC (2)
|
83.1 | 174.4 | 2.2E-54 | 140 |
| 2.60.40.10 | Receptor-type tyrosine-protein phosphatase S
2.60.40.10-FF-132959
|
2
|
SKCM (2)
|
74.9 | 215.1 | 6.9E-68 | 420 |