| Superfamily | Functional Family | Mutation Events | Mutation Types | DOPS | Incl. Bitscore | Incl. Evalue | Seqs |
|---|---|---|---|---|---|---|---|
| 3.30.70.680 | TNFRSF1A-associated via death domain
3.30.70.680-FF-53
|
4
|
PAAD (2)
UCEC (2)
|
93.8 | 208.3 | 1.5E-64 | 52 |
| 3.40.50.1480 | Putative adenosylhomocysteinase 3
3.40.50.1480-FF-2846
|
4
|
UCEC (2)
GBM (2)
|
90.9 | 110.5 | 1.6E-33 | 1417 |
| 3.40.50.1820 | Bifunctional epoxide hydrolase 2
3.40.50.1820-FF-115289
|
6
|
STAD (2)
UCEC (2)
LUSC (2)
|
90.3 | 233.5 | 2.1E-70 | 1152 |
| 3.40.50.1820 | Protease II (Oligopeptidase B)
3.40.50.1820-FF-115346
|
4
|
UCEC (4)
|
94.5 | 238.9 | 1.6E-71 | 3034 |
| 3.40.50.1820 | Putative animal-type fatty acid synthase
3.40.50.1820-FF-115364
|
2
|
UCEC (2)
|
83.4 | 193.1 | 1.4E-59 | 111 |
| 3.40.50.2300 | Gamma-aminobutyric acid B receptor
3.40.50.2300-FF-150792
|
2
|
GBM (2)
|
75.9 | 346.9 | 5.4E-107 | 68 |
| 1.10.10.430 | Protein phosphatase 1A isoform 1
1.10.10.430-FF-10
|
8
|
COAD (2)
STAD (2)
SKCM (2)
LGG (2)
|
71.0 | 130.1 | 8.1E-41 | 409 |
| 1.10.506.10 | Plexin-B2
1.10.506.10-FF-1279
|
12
|
STAD (2)
UCEC (2)
COAD (2)
LUAD (2)
READ (2)
BLCA (2)
|
82.3 | 553.7 | 1.1E-170 | 127 |
| 1.10.506.10 | Neurofibromin 1, isoform B
1.10.506.10-FF-1331
|
4
|
HNSC (2)
UCEC (2)
|
90.7 | 179.8 | 4.3E-55 | 271 |
| 3.30.450.40 | Rod cGMP-specific 3',5'-cyclic phosphodiesterase alpha-subunit
3.30.450.40-FF-30324
|
2
|
SKCM (2)
|
94.7 | 261.2 | 4.3E-80 | 269 |
| 1.10.12.10 | Testis-specific chromodomain protein Y 2
1.10.12.10-FF-5670
|
2
|
LUSC (2)
|
83.9 | 107.1 | 1.8E-33 | 139 |
| 2.30.130.10 | 60S ribosome subunit biogenesis protein
2.30.130.10-FF-4587
|
2
|
UCEC (2)
|
96.0 | 139.8 | 4.6E-43 | 1079 |
| 3.30.540.10 | Uncharacterised protein
3.30.540.10-FF-6473
|
6
|
UCEC (2)
PRAD (2)
STAD (2)
|
83.0 | 221.3 | 3.7E-68 | 128 |
| 1.25.40.180 | Programmed cell death protein 4
1.25.40.180-FF-4276
|
2
|
UCS (2)
|
71.4 | 249.5 | 4.5E-77 | 91 |
| 1.25.40.180 | Nuclear cap-binding protein subunit 1
1.25.40.180-FF-4407
|
2
|
CESC (2)
|
87.3 | 164.8 | 4.5E-51 | 353 |
| 2.10.70.10 | Complement factor H-related 1
2.10.70.10-FF-17148
|
2
|
SKCM (2)
|
90.1 | 101.2 | 1.0E-31 | 82 |
| 2.60.120.10 | Rap guanine nucleotide exchange factor 4
2.60.120.10-FF-16193
|
2
|
STAD (2)
|
80.6 | 251.5 | 2.0E-77 | 332 |
| 2.60.40.10 | Transcription factor COE1, putative
2.60.40.10-FF-79153
|
16
|
BLCA (2)
LUSC (2)
HNSC (2)
LUAD (2)
COAD (2)
UCEC (2)
READ (2)
ESCA (2)
|
81.3 | 144.6 | 1.4E-44 | 1153 |
| 2.60.40.10 | Cytotoxic T-lymphocyte protein 4
2.60.40.10-FF-131974
|
2
|
SARC (2)
|
79.2 | 224.0 | 1.2E-69 | 72 |
| 2.60.40.10 | T-cell-specific surface glycoprotein CD28
2.60.40.10-FF-133225
|
2
|
COAD (2)
|
70.2 | 237.4 | 9.3E-74 | 69 |