| Superfamily | Functional Family | Mutation Events | Mutation Types | DOPS | Incl. Bitscore | Incl. Evalue | Seqs |
|---|---|---|---|---|---|---|---|
| 2.60.40.10 | Cell surface glycoprotein CD200 receptor 1
2.60.40.10-FF-135779
|
4
|
UCEC (4)
|
78.0 | 150.4 | 1.9E-47 | 44 |
| 2.60.40.10 | Kinase insert domain receptor
2.60.40.10-FF-136136
|
4
|
UCEC (2)
LUAD (2)
|
96.0 | 101.4 | 6.9E-31 | 601 |
| 2.60.40.10 | Mutant CD8 alpha antigen
2.60.40.10-FF-136244
|
2
|
LUAD (2)
|
85.9 | 175.2 | 6.7E-55 | 26 |
| 2.60.40.10 | Nuclear factor of-activated T-cells, cytoplasmic 1
2.60.40.10-FF-137250
|
2
|
UCEC (2)
|
93.8 | 131.9 | 1.6E-40 | 442 |
| 2.60.40.10 | Osteoclast-associated immunoglobulin-like receptor
2.60.40.10-FF-137342
|
2
|
UCEC (2)
|
89.0 | 103.5 | 1.3E-32 | 53 |
| 3.30.497.10 | Serpin B5
3.30.497.10-FF-4739
|
8
|
UCEC (4)
LUSC (2)
KIRC (2)
|
88.1 | 244.3 | 3.9E-75 | 81 |
| 3.30.497.10 | Heparin cofactor 2
3.30.497.10-FF-4894
|
2
|
KIRC (2)
|
76.6 | 310.3 | 2.1E-95 | 57 |
| 3.30.497.10 | Leukocyte elastase inhibitor B
3.30.497.10-FF-4980
|
4
|
SKCM (4)
|
89.3 | 153.9 | 1.8E-46 | 874 |
| 3.40.50.2300 | Metabotropic glutamate receptor 5
3.40.50.2300-FF-6367
|
18
|
SARC (2)
MESO (2)
COAD (2)
LUAD (2)
SKCM (4)
STAD (2)
UCEC (2)
PAAD (2)
|
85.5 | 228.1 | 3.6E-70 | 189 |
| 3.90.1180.10 | 50S ribosomal protein L13
3.90.1180.10-FF-2128
|
4
|
LUAD (2)
SKCM (2)
|
92.2 | 110.4 | 1.1E-32 | 3224 |
| 3.90.850.10 | Probable fumarylacetoacetase (Fumarylacetoacetate hydrolase) protein
3.90.850.10-FF-5343
|
2
|
BLCA (2)
|
82.8 | 417.2 | 1.5E-126 | 1580 |
| 2.60.200.20 | Centrosomal protein of 170 kDa
2.60.200.20-FF-8129
|
8
|
STAD (2)
UCEC (4)
READ (2)
|
77.1 | 156.1 | 4.3E-48 | 256 |
| 2.60.200.20 | E3 ubiquitin-protein ligase RNF8
2.60.200.20-FF-8161
|
4
|
LGG (2)
BLCA (2)
|
88.8 | 156.0 | 2.4E-48 | 106 |
| 2.60.200.20 | Kinesin-like protein unc-104
2.60.200.20-FF-8178
|
8
|
LUAD (2)
UCEC (4)
SKCM (2)
|
82.6 | 131.5 | 5.0E-40 | 854 |
| 3.60.20.10 | Proteasome subunit beta type
3.60.20.10-FF-15794
|
2
|
LUSC (2)
|
90.6 | 271.7 | 5.8E-83 | 500 |
| 3.60.20.10 | Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1
3.60.20.10-FF-15819
|
8
|
STAD (2)
GBM (2)
UCEC (4)
|
88.7 | 197.4 | 8.8E-59 | 1971 |
| 3.90.1110.10 | RNA polymerase II subunit
3.90.1110.10-FF-1871
|
4
|
DLBC (2)
UCEC (2)
|
89.9 | 220.3 | 6.6E-67 | 1605 |
| 3.90.1110.10 | DNA-directed RNA polymerase
3.90.1110.10-FF-1889
|
16
|
UCEC (8)
COAD (2)
LUAD (2)
BRCA (2)
UCS (2)
|
92.0 | 193.7 | 5.5E-59 | 855 |
| 1.20.58.390 | Gamma-aminobutyric acid receptor subunit alpha-2
1.20.58.390-FF-2648
|
4
|
SKCM (2)
UCEC (2)
|
73.3 | 104.9 | 2.8E-31 | 1145 |
| 1.20.58.390 | Acetylcholine receptor subunit alpha
1.20.58.390-FF-2652
|
2
|
CESC (2)
|
82.4 | 141.1 | 7.0E-43 | 1197 |