| Superfamily | Functional Family | Mutation Events | Mutation Types | DOPS | Incl. Bitscore | Incl. Evalue | Seqs |
|---|---|---|---|---|---|---|---|
| 1.10.506.10 | Neurofibromin 1, isoform B
1.10.506.10-FF-1331
|
4
|
HNSC (2)
UCEC (2)
|
90.7 | 179.8 | 4.3E-55 | 271 |
| 3.30.450.40 | Rod cGMP-specific 3',5'-cyclic phosphodiesterase alpha-subunit
3.30.450.40-FF-30324
|
2
|
SKCM (2)
|
94.7 | 261.2 | 4.3E-80 | 269 |
| 1.10.12.10 | Testis-specific chromodomain protein Y 2
1.10.12.10-FF-5670
|
2
|
LUSC (2)
|
83.9 | 107.1 | 1.8E-33 | 139 |
| 1.20.58.390 | Gamma-aminobutyric acid receptor subunit alpha-2
1.20.58.390-FF-2648
|
4
|
SKCM (2)
UCEC (2)
|
73.3 | 104.9 | 2.8E-31 | 1145 |
| 1.20.58.390 | Acetylcholine receptor subunit alpha
1.20.58.390-FF-2652
|
2
|
CESC (2)
|
82.4 | 141.1 | 7.0E-43 | 1197 |
| 3.40.50.1240 | Ubiquitin-associated and SH3 domain-containing protein B
3.40.50.1240-FF-13397
|
26
|
CHOL (2)
GBM (2)
SKCM (10)
UCEC (6)
BRCA (2)
MESO (2)
LUSC (2)
|
81.6 | 174.1 | 6.3E-53 | 506 |
| 3.40.800.10 | Arginase, non-hepatic 1
3.40.800.10-FF-2194
|
2
|
UCEC (2)
|
92.2 | 280.9 | 6.3E-85 | 3338 |
| 3.40.800.10 | Putative agmatinase 2
3.40.800.10-FF-2199
|
2
|
HNSC (2)
|
95.5 | 312.4 | 2.1E-94 | 37605 |
| 2.170.300.10 | Tyrosine-protein kinase receptor Tie-1
2.170.300.10-FF-7750
|
2
|
SKCM (2)
|
80.8 | 169.9 | 3.1E-52 | 175 |
| 2.30.250.10 | Probable M18 family aminopeptidase 2
2.30.250.10-FF-811
|
2
|
GBM (2)
|
94.5 | 106.6 | 2.1E-32 | 2146 |
| 2.40.70.10 | Beta-site APP-cleaving enzyme 1
2.40.70.10-FF-22817
|
20
|
LIHC (2)
UCEC (4)
STAD (2)
PRAD (4)
SKCM (4)
COAD (2)
LUAD (2)
|
80.0 | 373.0 | 4.3E-114 | 172 |
| 2.40.70.10 | Beta-site APP-cleaving enzyme 1
2.40.70.10-FF-22859
|
4
|
UCEC (4)
|
78.5 | 202.4 | 9.6E-63 | 98 |
| 2.40.70.10 | Cathepsin D (A01 family)
2.40.70.10-FF-23002
|
6
|
GBM (2)
UCEC (2)
LUAD (2)
|
87.2 | 142.9 | 9.0E-44 | 362 |
| 2.60.40.150 | Small nuclear ribonucleoprotein 200kDa
2.60.40.150-FF-15495
|
2
|
UCEC (2)
|
88.7 | 133.5 | 3.9E-41 | 388 |
| 2.60.40.150 | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
2.60.40.150-FF-15597
|
108
|
BLCA (4)
BRCA (38)
SARC (2)
STAD (16)
UCEC (18)
GBM (2)
TGCT (2)
HNSC (6)
COAD (8)
LGG (4)
LUAD (2)
PRAD (2)
UCS (2)
CESC (2)
|
87.7 | 115.0 | 1.6E-35 | 229 |
| 3.30.870.10 | Mitochondrial cardiolipin hydrolase
3.30.870.10-FF-12790
|
14
|
STAD (2)
DLBC (2)
BLCA (2)
KIRP (2)
CESC (2)
UCEC (4)
|
93.2 | 232.1 | 9.3E-72 | 52 |
| 3.30.870.10 | Tyrosyl-DNA phosphodiesterase 1
3.30.870.10-FF-12826
|
2
|
LUSC (2)
|
91.6 | 171.5 | 1.1E-52 | 174 |
| 1.10.10.10 | Anaphase-promoting complex subunit 2
1.10.10.10-FF-159555
|
4
|
BLCA (4)
|
70.8 | 150.6 | 4.6E-47 | 76 |
| 1.10.10.10 | DEP domain-containing protein 1A
1.10.10.10-FF-263040
|
2
|
HNSC (2)
|
93.4 | 151.6 | 1.8E-47 | 201 |
| 1.10.10.10 | cDNA FLJ58509, highly similar to Cullin-1
1.10.10.10-FF-264801
|
6
|
UCEC (2)
STAD (2)
LUAD (2)
|
88.9 | 133.0 | 3.4E-41 | 363 |