| Superfamily | Functional Family | Mutation Events | Mutation Types | DOPS | Incl. Bitscore | Incl. Evalue | Seqs |
|---|---|---|---|---|---|---|---|
| 2.60.200.20 | E3 ubiquitin-protein ligase RNF8
2.60.200.20-FF-8161
|
4
|
LGG (2)
BLCA (2)
|
88.8 | 156.0 | 2.4E-48 | 106 |
| 2.60.200.20 | Kinesin-like protein unc-104
2.60.200.20-FF-8178
|
8
|
LUAD (2)
UCEC (4)
SKCM (2)
|
82.6 | 131.5 | 5.0E-40 | 854 |
| 3.40.630.10 | Aminoacylase-1
3.40.630.10-FF-34417
|
6
|
BRCA (2)
COAD (2)
BLCA (2)
|
89.8 | 274.9 | 3.3E-84 | 238 |
| 3.40.630.10 | Glutaminyl-peptide cyclotransferase (Glutaminyl cyclase)
3.40.630.10-FF-34591
|
2
|
STAD (2)
|
89.9 | 359.3 | 1.9E-109 | 291 |
| 3.40.630.10 | Glutamate carboxypeptidase 2 homolog
3.40.630.10-FF-34828
|
2
|
SKCM (2)
|
93.9 | 159.3 | 1.3E-47 | 1019 |
| 2.30.130.10 | 60S ribosome subunit biogenesis protein
2.30.130.10-FF-4587
|
2
|
UCEC (2)
|
96.0 | 139.8 | 4.6E-43 | 1079 |
| 3.30.540.10 | Uncharacterised protein
3.30.540.10-FF-6473
|
6
|
UCEC (2)
PRAD (2)
STAD (2)
|
83.0 | 221.3 | 3.7E-68 | 128 |
| 3.30.800.10 | Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha
3.30.800.10-FF-688
|
6
|
BLCA (2)
CESC (4)
|
83.0 | 243.5 | 2.1E-74 | 855 |
| 3.60.10.10 | Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1
3.60.10.10-FF-13379
|
2
|
KIRP (2)
|
87.5 | 537.8 | 7.8E-164 | 208 |
| 3.60.10.10 | DNA-(apurinic or apyrimidinic site) lyase
3.60.10.10-FF-13471
|
4
|
LIHC (2)
UCEC (2)
|
92.2 | 317.5 | 1.8E-96 | 2531 |
| 3.60.10.10 | Tyrosyl-DNA phosphodiesterase 2
3.60.10.10-FF-13509
|
4
|
STAD (4)
|
86.2 | 266.6 | 1.0E-81 | 123 |
| 1.10.3630.10 | Golgi phosphoprotein 3-like protein
1.10.3630.10-FF-298
|
6
|
READ (2)
UCEC (2)
COAD (2)
|
82.9 | 301.5 | 7.1E-92 | 717 |
| 2.60.40.150 | Phosphoinositide phospholipase C
2.60.40.150-FF-15221
|
6
|
SKCM (6)
|
89.5 | 154.5 | 1.8E-47 | 396 |
| 2.60.40.150 | Regulating synaptic membrane exocytosis 2
2.60.40.150-FF-15294
|
2
|
SKCM (2)
|
92.9 | 220.7 | 1.8E-67 | 1599 |
| 2.60.40.150 | X-linked retinitis pigmentosa GTPase regulator-interacting protein 1
2.60.40.150-FF-15398
|
6
|
UCEC (4)
COAD (2)
|
92.5 | 260.8 | 3.3E-80 | 95 |
| 1.10.10.10 | Anaphase-promoting complex subunit 2
1.10.10.10-FF-159555
|
4
|
BLCA (4)
|
70.8 | 150.6 | 4.6E-47 | 76 |
| 1.10.10.10 | ETS-related transcription factor Elf-3
1.10.10.10-FF-262918
|
2
|
LIHC (2)
|
84.4 | 136.9 | 4.2E-42 | 250 |
| 1.10.10.10 | Transcription factor Dp-2, putative
1.10.10.10-FF-264734
|
2
|
UCEC (2)
|
86.9 | 127.9 | 3.1E-39 | 773 |
| 1.10.150.60 | Lysine-specific demethylase 5B
1.10.150.60-FF-743
|
8
|
BLCA (2)
BRCA (2)
READ (2)
HNSC (2)
|
70.9 | 187.2 | 2.8E-58 | 111 |
| 1.10.150.80 | Werner syndrome ATP-dependent helicase
1.10.150.80-FF-3214
|
2
|
LUAD (2)
|
75.2 | 146.8 | 3.5E-46 | 45 |