| Superfamily | Functional Family | Mutation Events | Mutation Types | DOPS | Incl. Bitscore | Incl. Evalue | Seqs |
|---|---|---|---|---|---|---|---|
| 2.40.70.10 | Beta-site APP-cleaving enzyme 1
2.40.70.10-FF-22859
|
4
|
UCEC (4)
|
78.5 | 202.4 | 9.6E-63 | 98 |
| 2.40.70.10 | Cathepsin D (A01 family)
2.40.70.10-FF-23002
|
6
|
GBM (2)
UCEC (2)
LUAD (2)
|
87.2 | 142.9 | 9.0E-44 | 362 |
| 3.40.1110.10 | Copper-transporting ATPase 1
3.40.1110.10-FF-15453
|
8
|
LUAD (2)
STAD (4)
CESC (2)
|
76.5 | 214.4 | 2.4E-66 | 97 |
| 1.10.790.10 | Major prion protein
1.10.790.10-FF-74
|
2
|
UCEC (2)
|
89.0 | 123.8 | 2.7E-39 | 822 |
| 1.25.40.180 | Programmed cell death protein 4
1.25.40.180-FF-4276
|
2
|
UCS (2)
|
71.4 | 249.5 | 4.5E-77 | 91 |
| 1.25.40.180 | Nuclear cap-binding protein subunit 1
1.25.40.180-FF-4407
|
2
|
CESC (2)
|
87.3 | 164.8 | 4.5E-51 | 353 |
| 2.10.70.10 | Complement receptor type 1
2.10.70.10-FF-16845
|
2
|
COAD (2)
|
71.8 | 127.4 | 6.3E-40 | 36 |
| 2.10.70.10 | Platelet complement factor H
2.10.70.10-FF-16894
|
8
|
SKCM (8)
|
91.8 | 107.5 | 1.1E-33 | 65 |
| 2.10.70.10 | Complement C2 isoform 1
2.10.70.10-FF-16924
|
8
|
SKCM (6)
LUSC (2)
|
80.8 | 104.9 | 9.5E-33 | 88 |
| 2.10.70.10 | Membrane cofactor protein
2.10.70.10-FF-16929
|
4
|
UCEC (2)
LGG (2)
|
72.8 | 112.2 | 1.7E-35 | 28 |
| 2.10.70.10 | Complement decay-accelerating factor, GPI-anchored
2.10.70.10-FF-16956
|
2
|
UCEC (2)
|
75.5 | 119.6 | 1.2E-37 | 45 |
| 2.40.33.10 | Pyruvate kinase PKM
2.40.33.10-FF-1967
|
4
|
LUSC (2)
SKCM (2)
|
79.4 | 183.3 | 2.6E-57 | 181 |
| 2.60.40.10 | Transcription factor COE1, putative
2.60.40.10-FF-79153
|
16
|
BLCA (2)
LUSC (2)
HNSC (2)
LUAD (2)
COAD (2)
UCEC (2)
READ (2)
ESCA (2)
|
81.3 | 144.6 | 1.4E-44 | 1153 |
| 2.60.40.10 | C-kit receptor tyrosine kinase
2.60.40.10-FF-132947
|
2
|
HNSC (2)
|
83.1 | 174.4 | 2.2E-54 | 140 |
| 2.60.40.10 | Receptor-type tyrosine-protein phosphatase S
2.60.40.10-FF-132959
|
2
|
SKCM (2)
|
74.9 | 215.1 | 6.9E-68 | 420 |
| 2.60.40.10 | OX-2 membrane glycoprotein
2.60.40.10-FF-133088
|
4
|
BLCA (2)
UCEC (2)
|
73.3 | 209.1 | 3.1E-65 | 59 |
| 2.60.40.10 | Interleukin-12 subunit beta
2.60.40.10-FF-133103
|
2
|
LUSC (2)
|
83.3 | 187.7 | 1.6E-58 | 66 |
| 2.60.40.10 | Filamin C isoform 11
2.60.40.10-FF-134418
|
4
|
SKCM (2)
LUSC (2)
|
81.7 | 171.9 | 3.1E-53 | 248 |
| 2.60.40.10 | cDNA FLJ60251, highly similar to Contactin-6
2.60.40.10-FF-134423
|
12
|
SKCM (6)
COAD (4)
UCEC (2)
|
74.1 | 158.2 | 5.7E-49 | 315 |
| 2.60.40.10 | Filamin A, alpha isoform 2 (Predicted)
2.60.40.10-FF-134430
|
14
|
SKCM (6)
PAAD (2)
LGG (2)
LUSC (2)
ESCA (2)
|
93.7 | 143.4 | 3.4E-44 | 350 |