| Superfamily | Functional Family | Mutation Events | Mutation Types | DOPS | Incl. Bitscore | Incl. Evalue | Seqs |
|---|---|---|---|---|---|---|---|
| 3.20.20.330 | Methionine synthase (5-methyltetrahydrofolate--homocysteine methyltransferase)
3.20.20.330-FF-1374
|
6
|
LUSC (2)
SKCM (4)
|
92.7 | 296.3 | 3.1E-89 | 2744 |
| 3.40.50.1240 | Ubiquitin-associated and SH3 domain-containing protein B
3.40.50.1240-FF-13397
|
26
|
CHOL (2)
GBM (2)
SKCM (10)
UCEC (6)
BRCA (2)
MESO (2)
LUSC (2)
|
81.6 | 174.1 | 6.3E-53 | 506 |
| 3.30.540.10 | Uncharacterised protein
3.30.540.10-FF-6473
|
6
|
UCEC (2)
PRAD (2)
STAD (2)
|
83.0 | 221.3 | 3.7E-68 | 128 |
| 3.30.800.10 | Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha
3.30.800.10-FF-688
|
6
|
BLCA (2)
CESC (4)
|
83.0 | 243.5 | 2.1E-74 | 855 |
| 3.90.470.10 | 39S ribosomal protein L22, mitochondrial
3.90.470.10-FF-1953
|
6
|
UCEC (4)
CESC (2)
|
85.9 | 240.6 | 4.3E-74 | 112 |
| 3.40.800.10 | Arginase, non-hepatic 1
3.40.800.10-FF-2194
|
2
|
UCEC (2)
|
92.2 | 280.9 | 6.3E-85 | 3338 |
| 3.40.800.10 | Putative agmatinase 2
3.40.800.10-FF-2199
|
2
|
HNSC (2)
|
95.5 | 312.4 | 2.1E-94 | 37605 |
| 3.60.10.10 | Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1
3.60.10.10-FF-13379
|
2
|
KIRP (2)
|
87.5 | 537.8 | 7.8E-164 | 208 |
| 3.60.10.10 | DNA-(apurinic or apyrimidinic site) lyase
3.60.10.10-FF-13471
|
4
|
LIHC (2)
UCEC (2)
|
92.2 | 317.5 | 1.8E-96 | 2531 |
| 3.60.10.10 | Tyrosyl-DNA phosphodiesterase 2
3.60.10.10-FF-13509
|
4
|
STAD (4)
|
86.2 | 266.6 | 1.0E-81 | 123 |
| 2.170.300.10 | Tyrosine-protein kinase receptor Tie-1
2.170.300.10-FF-7750
|
2
|
SKCM (2)
|
80.8 | 169.9 | 3.1E-52 | 175 |
| 1.10.3630.10 | Golgi phosphoprotein 3-like protein
1.10.3630.10-FF-298
|
6
|
READ (2)
UCEC (2)
COAD (2)
|
82.9 | 301.5 | 7.1E-92 | 717 |
| 2.30.250.10 | Probable M18 family aminopeptidase 2
2.30.250.10-FF-811
|
2
|
GBM (2)
|
94.5 | 106.6 | 2.1E-32 | 2146 |
| 2.60.40.150 | Synaptotagmin 1, isoform I
2.60.40.150-FF-15108
|
2
|
UCEC (2)
|
89.9 | 206.1 | 4.2E-63 | 775 |
| 2.40.70.10 | Beta-site APP-cleaving enzyme 1
2.40.70.10-FF-22817
|
20
|
LIHC (2)
UCEC (4)
STAD (2)
PRAD (4)
SKCM (4)
COAD (2)
LUAD (2)
|
80.0 | 373.0 | 4.3E-114 | 172 |
| 2.40.70.10 | Beta-site APP-cleaving enzyme 1
2.40.70.10-FF-22859
|
4
|
UCEC (4)
|
78.5 | 202.4 | 9.6E-63 | 98 |
| 2.40.70.10 | Cathepsin D (A01 family)
2.40.70.10-FF-23002
|
6
|
GBM (2)
UCEC (2)
LUAD (2)
|
87.2 | 142.9 | 9.0E-44 | 362 |
| 2.40.128.20 | Beta-lactoglobulin I
2.40.128.20-FF-5792
|
4
|
UCEC (2)
BRCA (2)
|
90.9 | 192.4 | 1.2E-59 | 53 |
| 2.40.128.20 | Complement component C8 gamma chain
2.40.128.20-FF-5910
|
2
|
CESC (2)
|
95.4 | 162.9 | 1.2E-50 | 41 |
| 2.60.40.150 | Phosphoinositide phospholipase C
2.60.40.150-FF-15154
|
2
|
SKCM (2)
|
73.1 | 276.3 | 2.2E-85 | 62 |