| Superfamily | Functional Family | Mutation Events | Mutation Types | DOPS | Incl. Bitscore | Incl. Evalue | Seqs |
|---|---|---|---|---|---|---|---|
| 2.30.29.30 | Oxysterol-binding protein-related protein 5
2.30.29.30-FF-21746
|
2
|
HNSC (2)
|
71.7 | 227.6 | 3.6E-70 | 242 |
| 2.30.29.30 | Cytoplasmic tyrosine-protein kinase BMX
2.30.29.30-FF-22501
|
22
|
COAD (4)
LUAD (4)
SKCM (4)
UCEC (8)
STAD (2)
|
90.1 | 139.6 | 6.9E-43 | 387 |
| 2.30.29.30 | Growth factor receptor-bound protein 14
2.30.29.30-FF-22502
|
14
|
HNSC (2)
BLCA (4)
UCEC (2)
CESC (2)
KIRC (2)
SKCM (2)
|
86.5 | 165.2 | 1.2E-50 | 771 |
| 2.30.29.30 | FERM, RhoGEF and pleckstrin domain-containing protein 2
2.30.29.30-FF-22527
|
2
|
UCEC (2)
|
78.8 | 143.6 | 7.0E-45 | 103 |
| 2.30.29.30 | Actin-binding protein anillin
2.30.29.30-FF-22580
|
4
|
STAD (4)
|
95.6 | 132.9 | 4.5E-41 | 205 |
| 2.30.29.30 | Myotubularin-related protein 1
2.30.29.30-FF-22583
|
2
|
LGG (2)
|
83.1 | 101.5 | 5.5E-31 | 491 |
| 2.30.29.30 | Unconventional myosin-X
2.30.29.30-FF-22611
|
16
|
COAD (2)
STAD (4)
UCEC (10)
|
75.4 | 153.1 | 9.6E-48 | 105 |
| 2.30.29.30 | Syntrophin, basic 2
2.30.29.30-FF-22643
|
2
|
STAD (2)
|
86.5 | 107.8 | 1.4E-33 | 180 |
| 2.30.29.30 | Epidermal growth factor receptor kinase substrate 8
2.30.29.30-FF-22656
|
4
|
LUSC (2)
ACC (2)
|
94.4 | 139.4 | 1.0E-42 | 282 |
| 2.40.20.10 | Plasminogen
2.40.20.10-FF-1672
|
4
|
SKCM (4)
|
75.5 | 171.5 | 7.7E-54 | 48 |
| 2.40.20.10 | Prothrombin
2.40.20.10-FF-1688
|
4
|
STAD (2)
SKCM (2)
|
79.5 | 135.1 | 1.1E-42 | 49 |
| 2.40.20.10 | Urokinase-type plasminogen activator amino-terminal
2.40.20.10-FF-1699
|
2
|
STAD (2)
|
90.1 | 103.9 | 1.2E-31 | 445 |
| 3.30.2350.10 | Pseudouridine synthase, RluA family
3.30.2350.10-FF-8962
|
6
|
SKCM (2)
ESCA (2)
STAD (2)
|
88.0 | 138.4 | 1.9E-40 | 54758 |
| 3.30.565.10 | Probable DNA topoisomerase 2
3.30.565.10-FF-80675
|
12
|
BLCA (2)
SKCM (4)
COAD (4)
LIHC (2)
|
85.6 | 239.2 | 2.5E-72 | 1097 |
| 3.30.565.10 | Mismatch repair endonuclease pms1
3.30.565.10-FF-80732
|
6
|
STAD (2)
LUAD (2)
CESC (2)
|
85.9 | 253.1 | 5.8E-77 | 901 |
| 2.60.40.1170 | AP-2 complex subunit mu-1
2.60.40.1170-FF-1765
|
2
|
SKCM (2)
|
88.5 | 155.7 | 4.1E-48 | 2008 |
| 3.40.50.720 | Estradiol 17-beta-dehydrogenase 1
3.40.50.720-FF-284952
|
6
|
LUSC (2)
LUAD (2)
UCEC (2)
|
84.2 | 382.1 | 4.6E-117 | 61 |
| 3.40.50.720 | Hydroxysteroid dehydrogenase like 2
3.40.50.720-FF-285086
|
2
|
BLCA (2)
|
90.0 | 392.2 | 1.5E-119 | 948 |
| 3.40.50.720 | UDP-glucose 6-dehydrogenase 2
3.40.50.720-FF-285482
|
12
|
KIRP (2)
STAD (2)
UCEC (4)
BLCA (2)
COAD (2)
|
85.2 | 251.4 | 2.3E-76 | 1102 |
| 3.40.50.720 | NEDD8-activating enzyme E1 catalytic subunit
3.40.50.720-FF-285491
|
14
|
LUAD (2)
HNSC (2)
STAD (4)
UCEC (4)
ESCA (2)
|
81.6 | 304.7 | 8.0E-93 | 642 |