| Superfamily | Functional Family | Mutation Events | Mutation Types | DOPS | Incl. Bitscore | Incl. Evalue | Seqs |
|---|---|---|---|---|---|---|---|
| 2.30.29.30 | Oxysterol-binding protein-related protein 5
2.30.29.30-FF-21746
|
2
|
HNSC (2)
|
71.7 | 227.6 | 3.6E-70 | 242 |
| 2.30.29.30 | Numb homolog (Drosophila), isoform CRA_a
2.30.29.30-FF-21912
|
6
|
SKCM (4)
STAD (2)
|
79.1 | 196.7 | 2.0E-60 | 406 |
| 2.30.29.30 | Switch-associated protein 70
2.30.29.30-FF-22072
|
2
|
SKCM (2)
|
80.9 | 155.7 | 1.6E-48 | 136 |
| 2.30.29.30 | Rho guanine nucleotide exchange factor 9
2.30.29.30-FF-22085
|
10
|
STAD (4)
KIRP (2)
UCEC (4)
|
86.9 | 232.4 | 2.5E-71 | 361 |
| 2.30.29.30 | Mammalian enabled variant 11a
2.30.29.30-FF-22097
|
2
|
CESC (2)
|
93.6 | 167.9 | 1.5E-51 | 499 |
| 2.30.29.30 | RAC-beta serine/threonine-protein kinase A
2.30.29.30-FF-22238
|
120
|
BRCA (48)
THCA (10)
CESC (8)
LUAD (4)
PRAD (4)
STAD (2)
UCEC (16)
COAD (12)
SKCM (6)
LUSC (6)
BLCA (2)
HNSC (2)
|
91.7 | 162.8 | 3.8E-50 | 1420 |
| 2.30.29.30 | Sprouty-related, EVH1 domain-containing protein 2
2.30.29.30-FF-22102
|
6
|
LUAD (2)
UCEC (2)
LGG (2)
|
86.9 | 209.6 | 1.1E-64 | 430 |
| 2.30.29.30 | Docking protein 1 variant
2.30.29.30-FF-22459
|
2
|
UCEC (2)
|
90.6 | 146.6 | 1.7E-45 | 179 |
| 2.30.29.30 | Ran-specific GTPase-activating protein 1
2.30.29.30-FF-22132
|
2
|
UCEC (2)
|
90.3 | 207.3 | 2.0E-63 | 1077 |
| 2.30.29.30 | Unconventional myosin-X
2.30.29.30-FF-22254
|
6
|
LUAD (2)
LUSC (4)
|
71.3 | 132.1 | 3.0E-42 | 200 |
| 2.30.29.30 | Epidermal growth factor receptor kinase substrate 8
2.30.29.30-FF-22656
|
4
|
LUSC (2)
ACC (2)
|
94.4 | 139.4 | 1.0E-42 | 282 |
| 2.30.29.30 | Disabled homolog 1 (Drosophila)
2.30.29.30-FF-22263
|
2
|
SKCM (2)
|
86.0 | 218.1 | 6.6E-67 | 373 |
| 2.30.29.30 | Guanine nucleotide exchange factor
2.30.29.30-FF-22277
|
10
|
CESC (2)
STAD (2)
SARC (2)
HNSC (2)
SKCM (2)
|
87.1 | 145.5 | 1.7E-44 | 517 |
| 2.30.29.30 | Cytoplasmic tyrosine-protein kinase BMX
2.30.29.30-FF-22501
|
22
|
COAD (4)
LUAD (4)
SKCM (4)
UCEC (8)
STAD (2)
|
90.1 | 139.6 | 6.9E-43 | 387 |
| 2.30.29.30 | Growth factor receptor-bound protein 14
2.30.29.30-FF-22502
|
14
|
HNSC (2)
BLCA (4)
UCEC (2)
CESC (2)
KIRC (2)
SKCM (2)
|
86.5 | 165.2 | 1.2E-50 | 771 |
| 2.30.29.30 | mRNA-decapping enzyme subunit 1
2.30.29.30-FF-22949
|
2
|
SKCM (2)
|
79.6 | 109.5 | 2.5E-33 | 604 |
| 2.30.29.30 | FERM, RhoGEF and pleckstrin domain-containing protein 2
2.30.29.30-FF-22527
|
2
|
UCEC (2)
|
78.8 | 143.6 | 7.0E-45 | 103 |
| 2.30.29.30 | Actin-binding protein anillin
2.30.29.30-FF-22580
|
4
|
STAD (4)
|
95.6 | 132.9 | 4.5E-41 | 205 |
| 2.30.29.30 | cDNA FLJ53435, highly similar to Ezrin
2.30.29.30-FF-22306
|
10
|
UCEC (6)
LGG (2)
READ (2)
|
97.6 | 153.9 | 3.1E-47 | 1358 |
| 2.30.29.30 | APBB2 protein
2.30.29.30-FF-22332
|
4
|
LIHC (2)
CHOL (2)
|
76.7 | 207.8 | 4.4E-64 | 185 |