| Superfamily | Functional Family | Mutation Events | Mutation Types | DOPS | Incl. Bitscore | Incl. Evalue | Seqs |
|---|---|---|---|---|---|---|---|
| 3.30.505.10 | Signal transducer and activator of transcription
3.30.505.10-FF-4254
|
2
|
UCEC (2)
|
80.1 | 132.6 | 1.5E-40 | 533 |
| 3.30.505.10 | Non-specific protein-tyrosine kinase
3.30.505.10-FF-4276
|
2
|
SKCM (2)
|
92.7 | 135.8 | 1.5E-41 | 637 |
| 3.30.505.10 | Phosphoinositide phospholipase C
3.30.505.10-FF-4278
|
14
|
READ (2)
UCEC (4)
CESC (4)
SKCM (2)
STAD (2)
|
91.7 | 142.2 | 6.4E-44 | 380 |
| 3.30.505.10 | Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1
3.30.505.10-FF-4288
|
4
|
UCEC (2)
STAD (2)
|
85.4 | 106.9 | 6.9E-33 | 465 |
| 3.40.50.10470 | Putative methylthioribose-1-phosphate isomerase protein
3.40.50.10470-FF-1910
|
2
|
HNSC (2)
|
90.5 | 192.1 | 8.5E-58 | 1443 |
| 3.40.50.261 | ATP-citrate synthase subunit 1
3.40.50.261-FF-4818
|
2
|
PAAD (2)
|
85.9 | 229.9 | 7.3E-70 | 1203 |
| 3.40.50.261 | Succinyl-CoA ligase [ADP-forming] subunit alpha
3.40.50.261-FF-4912
|
2
|
UCEC (2)
|
88.7 | 211.9 | 9.0E-64 | 3590 |
| 3.40.50.261 | Succinyl-CoA ligase subunit beta
3.40.50.261-FF-4924
|
4
|
COAD (2)
UCEC (2)
|
98.2 | 127.1 | 1.2E-37 | 3364 |
| 3.90.79.10 | Diphosphoinositol polyphosphate phosphohydrolase 1
3.90.79.10-FF-21430
|
12
|
SKCM (2)
LUSC (2)
UCEC (6)
STAD (2)
|
70.3 | 216.9 | 7.1E-67 | 1082 |
| 1.10.510.10 | Fibroblast growth factor receptor 1
1.10.510.10-FF-21492
|
10
|
BLCA (4)
GBM (4)
KIRP (2)
|
79.3 | 257.9 | 1.9E-80 | 659 |
| 1.10.510.10 | Casein kinase II subunit alpha
1.10.510.10-FF-26544
|
18
|
COAD (4)
UCEC (6)
BLCA (2)
SKCM (2)
KIRP (2)
CESC (2)
|
84.2 | 241.4 | 3.0E-74 | 2712 |
| 1.10.510.10 | Receptor tyrosine-protein kinase erbB-4
1.10.510.10-FF-60677
|
102
|
LUAD (62)
UCEC (12)
BLCA (6)
STAD (4)
SKCM (6)
LUSC (4)
COAD (2)
PAAD (4)
UCS (2)
|
84.3 | 266.9 | 1.1E-82 | 437 |
| 1.10.510.10 | Tyrosine-protein kinase receptor TYRO3
1.10.510.10-FF-78966
|
6
|
SKCM (4)
KIRP (2)
|
88.1 | 229.1 | 7.7E-71 | 614 |
| 1.10.510.10 | Mitogen-activated protein kinase kinase
1.10.510.10-FF-78985
|
34
|
COAD (4)
LUAD (4)
STAD (10)
UCEC (6)
SKCM (4)
LIHC (2)
CESC (2)
BLCA (2)
|
84.4 | 149.7 | 7.5E-46 | 1730 |
| 1.10.510.10 | Inactive tyrosine-protein kinase 7
1.10.510.10-FF-79024
|
6
|
CESC (2)
SKCM (4)
|
82.4 | 244.8 | 2.5E-75 | 234 |
| 1.10.510.10 | Serine/Threonine kinase family protein
1.10.510.10-FF-79044
|
32
|
READ (4)
STAD (2)
SKCM (6)
HNSC (4)
UCEC (8)
COAD (4)
LUSC (2)
BLCA (2)
|
90.6 | 158.1 | 3.1E-48 | 1087 |
| 1.10.510.10 | Integrin-linked protein kinase, putative
1.10.510.10-FF-79444
|
4
|
UCEC (2)
STAD (2)
|
84.4 | 275.9 | 2.5E-85 | 354 |
| 1.10.510.10 | Insulin receptor
1.10.510.10-FF-79449
|
2
|
UCEC (2)
|
85.5 | 179.4 | 1.9E-56 | 77 |
| 3.40.50.10190 | Protein ECT2
3.40.50.10190-FF-6404
|
6
|
UCEC (2)
LUSC (2)
READ (2)
|
82.8 | 121.1 | 9.6E-38 | 94 |
| 3.40.50.10190 | PAX-interacting protein 1
3.40.50.10190-FF-8685
|
2
|
LUSC (2)
|
83.4 | 164.8 | 3.1E-51 | 118 |