| Superfamily | Functional Family | Mutation Events | Mutation Types | DOPS | Incl. Bitscore | Incl. Evalue | Seqs |
|---|---|---|---|---|---|---|---|
| 2.30.29.30 | Rho guanine nucleotide exchange factor 9
2.30.29.30-FF-22085
|
10
|
STAD (4)
KIRP (2)
UCEC (4)
|
86.9 | 232.4 | 2.5E-71 | 361 |
| 2.30.29.30 | Mammalian enabled variant 11a
2.30.29.30-FF-22097
|
2
|
CESC (2)
|
93.6 | 167.9 | 1.5E-51 | 499 |
| 2.30.29.30 | Sprouty-related, EVH1 domain-containing protein 2
2.30.29.30-FF-22102
|
6
|
LUAD (2)
UCEC (2)
LGG (2)
|
86.9 | 209.6 | 1.1E-64 | 430 |
| 2.30.29.30 | Ran-specific GTPase-activating protein 1
2.30.29.30-FF-22132
|
2
|
UCEC (2)
|
90.3 | 207.3 | 2.0E-63 | 1077 |
| 2.30.29.30 | mRNA-decapping enzyme subunit 1
2.30.29.30-FF-22949
|
2
|
SKCM (2)
|
79.6 | 109.5 | 2.5E-33 | 604 |
| 2.40.110.10 | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial
2.40.110.10-FF-14298
|
12
|
COAD (2)
BLCA (2)
LGG (2)
HNSC (2)
UCEC (2)
KIRP (2)
|
89.2 | 203.9 | 6.4E-63 | 333 |
| 2.40.110.10 | Acyl-CoA dehydrogenase family protein
2.40.110.10-FF-14341
|
2
|
HNSC (2)
|
98.6 | 158.9 | 1.4E-48 | 1806 |
| 3.30.2350.10 | Pseudouridine synthase, RluA family
3.30.2350.10-FF-8962
|
6
|
SKCM (2)
ESCA (2)
STAD (2)
|
88.0 | 138.4 | 1.9E-40 | 54758 |
| 3.30.70.1470 | Caspase 4, apoptosis-related cysteine peptidase
3.30.70.1470-FF-602
|
14
|
UCEC (4)
LUAD (4)
LUSC (2)
GBM (2)
STAD (2)
|
96.3 | 136.0 | 2.6E-42 | 139 |
| 3.30.900.10 | MAD2 mitotic arrest deficient-like 1
3.30.900.10-FF-576
|
2
|
BLCA (2)
|
90.0 | 282.3 | 8.2E-87 | 146 |
| 2.60.40.1170 | AP-2 complex subunit mu-1
2.60.40.1170-FF-1765
|
2
|
SKCM (2)
|
88.5 | 155.7 | 4.1E-48 | 2008 |
| 3.40.220.10 | Poly [ADP-ribose] polymerase 14
3.40.220.10-FF-5051
|
4
|
SKCM (4)
|
84.9 | 136.2 | 7.4E-41 | 1359 |
| 3.40.50.720 | Fatty acid synthase, putative
3.40.50.720-FF-285989
|
10
|
LIHC (2)
SKCM (4)
UCEC (2)
COAD (2)
|
89.4 | 328.3 | 3.4E-101 | 147 |
| 3.40.50.720 | Biliverdin reductase A
3.40.50.720-FF-286219
|
4
|
COAD (2)
UCEC (2)
|
70.8 | 202.7 | 5.8E-63 | 54 |
| 3.40.50.720 | Putative GDP-mannose 4,6-dehydratase
3.40.50.720-FF-286397
|
4
|
UCEC (2)
SKCM (2)
|
94.3 | 249.4 | 4.0E-75 | 2714 |
| 4.10.900.10 | Transcription factor 7-like 2
4.10.900.10-FF-590
|
4
|
UCEC (2)
STAD (2)
|
77.1 | 106.8 | 2.9E-33 | 165 |
| 2.40.150.20 | 50S ribosomal protein L14
2.40.150.20-FF-1393
|
2
|
BRCA (2)
|
94.2 | 159.5 | 1.3E-48 | 4973 |
| 3.40.50.1910 | Syntaxin-binding protein 3
3.40.50.1910-FF-204
|
12
|
CESC (2)
COAD (2)
UCEC (4)
LIHC (2)
STAD (2)
|
79.0 | 128.0 | 4.0E-40 | 53 |
| 3.90.550.10 | Putative n-acylneuraminate cytidylyltransferase
3.90.550.10-FF-64185
|
14
|
UCEC (6)
COAD (4)
SKCM (2)
BLCA (2)
|
82.3 | 381.4 | 5.2E-117 | 91 |
| 1.25.40.10 | Protein unc-45 homolog A
1.25.40.10-FF-145850
|
6
|
BRCA (2)
LUSC (2)
CESC (2)
|
90.5 | 151.7 | 7.2E-47 | 184 |