| Superfamily | Functional Family | Mutation Events | Mutation Types | DOPS | Incl. Bitscore | Incl. Evalue | Seqs |
|---|---|---|---|---|---|---|---|
| 2.30.29.30 | FERM, RhoGEF and pleckstrin domain-containing protein 2
2.30.29.30-FF-22527
|
2
|
UCEC (2)
|
78.8 | 143.6 | 7.0E-45 | 103 |
| 2.30.29.30 | Actin-binding protein anillin
2.30.29.30-FF-22580
|
4
|
STAD (4)
|
95.6 | 132.9 | 4.5E-41 | 205 |
| 2.30.29.30 | Myotubularin-related protein 1
2.30.29.30-FF-22583
|
2
|
LGG (2)
|
83.1 | 101.5 | 5.5E-31 | 491 |
| 2.30.29.30 | Unconventional myosin-X
2.30.29.30-FF-22611
|
16
|
COAD (2)
STAD (4)
UCEC (10)
|
75.4 | 153.1 | 9.6E-48 | 105 |
| 2.30.29.30 | TBC1 domain family member 2A
2.30.29.30-FF-22381
|
6
|
BLCA (2)
STAD (2)
COAD (2)
|
88.3 | 121.1 | 1.3E-37 | 116 |
| 2.40.110.10 | Acyl-CoA dehydrogenase family protein
2.40.110.10-FF-14341
|
2
|
HNSC (2)
|
98.6 | 158.9 | 1.4E-48 | 1806 |
| 2.30.29.30 | Syntrophin, basic 2
2.30.29.30-FF-22643
|
2
|
STAD (2)
|
86.5 | 107.8 | 1.4E-33 | 180 |
| 3.10.580.10 | Cystathionine beta-synthase
3.10.580.10-FF-15836
|
4
|
UCEC (4)
|
72.1 | 269.1 | 5.3E-83 | 107 |
| 2.40.20.10 | Plasminogen
2.40.20.10-FF-1672
|
4
|
SKCM (4)
|
75.5 | 171.5 | 7.7E-54 | 48 |
| 2.40.20.10 | Prothrombin
2.40.20.10-FF-1688
|
4
|
STAD (2)
SKCM (2)
|
79.5 | 135.1 | 1.1E-42 | 49 |
| 2.40.20.10 | Urokinase-type plasminogen activator amino-terminal
2.40.20.10-FF-1699
|
2
|
STAD (2)
|
90.1 | 103.9 | 1.2E-31 | 445 |
| 3.30.70.1470 | Caspase 4, apoptosis-related cysteine peptidase
3.30.70.1470-FF-602
|
14
|
UCEC (4)
LUAD (4)
LUSC (2)
GBM (2)
STAD (2)
|
96.3 | 136.0 | 2.6E-42 | 139 |
| 3.30.2350.10 | Pseudouridine synthase, RluA family
3.30.2350.10-FF-8962
|
6
|
SKCM (2)
ESCA (2)
STAD (2)
|
88.0 | 138.4 | 1.9E-40 | 54758 |
| 3.30.565.10 | Probable DNA topoisomerase 2
3.30.565.10-FF-80675
|
12
|
BLCA (2)
SKCM (4)
COAD (4)
LIHC (2)
|
85.6 | 239.2 | 2.5E-72 | 1097 |
| 2.60.40.1170 | AP-2 complex subunit mu-1
2.60.40.1170-FF-1765
|
2
|
SKCM (2)
|
88.5 | 155.7 | 4.1E-48 | 2008 |
| 3.30.565.10 | Mismatch repair endonuclease pms1
3.30.565.10-FF-80732
|
6
|
STAD (2)
LUAD (2)
CESC (2)
|
85.9 | 253.1 | 5.8E-77 | 901 |
| 3.40.50.410 | Anthrax toxin receptor 1
3.40.50.410-FF-19613
|
12
|
UCEC (4)
CESC (2)
LUSC (2)
READ (2)
LUAD (2)
|
92.6 | 207.2 | 2.2E-63 | 307 |
| 3.40.50.410 | 60 kDa SS-A/Ro ribonucleoprotein
3.40.50.410-FF-19655
|
2
|
BLCA (2)
|
86.8 | 263.4 | 3.9E-81 | 103 |
| 3.40.50.410 | ATP-dependent DNA helicase ku70
3.40.50.410-FF-19680
|
4
|
BLCA (2)
ESCA (2)
|
93.5 | 236.8 | 1.4E-72 | 134 |
| 1.20.58.70 | Syntaxin 1A
1.20.58.70-FF-2008
|
2
|
BLCA (2)
|
80.9 | 198.2 | 1.2E-60 | 799 |