| Superfamily | Functional Family | Mutation Events | Mutation Types | DOPS | Incl. Bitscore | Incl. Evalue | Seqs |
|---|---|---|---|---|---|---|---|
| 3.90.79.10 | ADP-ribose pyrophosphatase, mitochondrial
3.90.79.10-FF-21597
|
2
|
ACC (2)
|
94.5 | 157.0 | 2.7E-48 | 152 |
| 3.90.79.10 | Putative pre-mrna cleavage factor
3.90.79.10-FF-21635
|
6
|
KIRC (2)
HNSC (4)
|
92.3 | 194.2 | 3.9E-61 | 1612 |
| 3.90.79.10 | Probable 8-oxo-dGTP diphosphatase NUDT15
3.90.79.10-FF-21641
|
6
|
COAD (4)
READ (2)
|
90.1 | 177.0 | 6.0E-55 | 79 |
| 3.90.79.10 | Peroxisomal NADH pyrophosphatase NUDT12
3.90.79.10-FF-21658
|
2
|
SKCM (2)
|
92.7 | 134.0 | 3.4E-40 | 3553 |
| 1.10.510.10 | Probable serine/threonine-protein kinase FPV212
1.10.510.10-FF-79293
|
4
|
UCEC (2)
COAD (2)
|
88.6 | 357.7 | 1.8E-110 | 345 |
| 2.60.40.10 | Myosin-binding protein C, slow-type
2.60.40.10-FF-134722
|
2
|
UCEC (2)
|
91.1 | 154.9 | 3.6E-48 | 309 |
| 2.60.40.10 | T-cell surface glycoprotein CD8 beta chain
2.60.40.10-FF-134726
|
4
|
SKCM (4)
|
83.2 | 194.8 | 8.7E-61 | 38 |
| 2.60.40.10 | Filamin A, alpha isoform 2 (Predicted)
2.60.40.10-FF-134831
|
2
|
BRCA (2)
|
93.7 | 153.1 | 3.1E-47 | 277 |
| 2.60.40.10 | Cardiac titin N2BA isoform
2.60.40.10-FF-134864
|
2
|
GBM (2)
|
79.4 | 130.7 | 1.0E-41 | 63 |
| 2.60.40.10 | Interleukin-4 receptor subunit alpha
2.60.40.10-FF-134891
|
6
|
ESCA (2)
UCEC (2)
LUSC (2)
|
84.0 | 178.6 | 5.4E-56 | 35 |
| 2.60.40.10 | Kinase insert domain receptor
2.60.40.10-FF-136136
|
4
|
UCEC (2)
LUAD (2)
|
96.0 | 101.4 | 6.9E-31 | 601 |
| 2.60.40.10 | Mutant CD8 alpha antigen
2.60.40.10-FF-136244
|
2
|
LUAD (2)
|
85.9 | 175.2 | 6.7E-55 | 26 |
| 2.60.40.10 | T-cell immunoreceptor with Ig and ITIM domains
2.60.40.10-FF-138499
|
4
|
READ (2)
SKCM (2)
|
97.1 | 104.9 | 6.7E-33 | 70 |
| 3.40.50.1820 | Lysosomal Pro-X carboxypeptidase, putative
3.40.50.1820-FF-115164
|
14
|
ESCA (2)
UCEC (6)
SKCM (2)
LUSC (4)
|
92.3 | 386.8 | 4.6E-118 | 232 |
| 3.40.50.2300 | Metabotropic glutamate receptor 5
3.40.50.2300-FF-6367
|
18
|
SARC (2)
MESO (2)
COAD (2)
LUAD (2)
SKCM (4)
STAD (2)
UCEC (2)
PAAD (2)
|
85.5 | 228.1 | 3.6E-70 | 189 |
| 3.40.50.2300 | Gamma-aminobutyric acid B receptor
3.40.50.2300-FF-150792
|
2
|
GBM (2)
|
75.9 | 346.9 | 5.4E-107 | 68 |
| 3.40.449.10 | Phosphoenolpyruvate carboxykinase [GTP], mitochondrial
3.40.449.10-FF-1486
|
16
|
BLCA (2)
COAD (2)
SKCM (12)
|
93.9 | 197.7 | 1.3E-59 | 1951 |
| 3.40.630.10 | Glutaminyl-peptide cyclotransferase (Glutaminyl cyclase)
3.40.630.10-FF-34591
|
2
|
STAD (2)
|
89.9 | 359.3 | 1.9E-109 | 291 |
| 3.40.630.10 | Glutamate carboxypeptidase 2 homolog
3.40.630.10-FF-34828
|
2
|
SKCM (2)
|
93.9 | 159.3 | 1.3E-47 | 1019 |
| 2.30.130.10 | 60S ribosome subunit biogenesis protein
2.30.130.10-FF-4587
|
2
|
UCEC (2)
|
96.0 | 139.8 | 4.6E-43 | 1079 |