| Superfamily | Functional Family | Mutation Events | Mutation Types | DOPS | Incl. Bitscore | Incl. Evalue | Seqs |
|---|---|---|---|---|---|---|---|
| 3.40.50.410 | ATP-dependent DNA helicase ku70
3.40.50.410-FF-19680
|
4
|
BLCA (2)
ESCA (2)
|
93.5 | 236.8 | 1.4E-72 | 134 |
| 3.40.220.10 | Poly [ADP-ribose] polymerase 14
3.40.220.10-FF-5051
|
4
|
SKCM (4)
|
84.9 | 136.2 | 7.4E-41 | 1359 |
| 2.60.40.1170 | AP-2 complex subunit mu-1
2.60.40.1170-FF-1765
|
2
|
SKCM (2)
|
88.5 | 155.7 | 4.1E-48 | 2008 |
| 3.30.1780.10 | Ketimine reductase mu-crystallin
3.30.1780.10-FF-1447
|
10
|
COAD (2)
STAD (2)
BLCA (4)
CESC (2)
|
88.8 | 155.1 | 2.1E-48 | 63 |
| 1.20.58.70 | Syntaxin 1A
1.20.58.70-FF-2008
|
2
|
BLCA (2)
|
80.9 | 198.2 | 1.2E-60 | 799 |
| 3.40.50.720 | Estradiol 17-beta-dehydrogenase 1
3.40.50.720-FF-284952
|
6
|
LUSC (2)
LUAD (2)
UCEC (2)
|
84.2 | 382.1 | 4.6E-117 | 61 |
| 3.40.50.720 | Glyceraldehyde-3-phosphate dehydrogenase
3.40.50.720-FF-174011
|
6
|
SKCM (4)
UCEC (2)
|
83.4 | 156.6 | 6.2E-48 | 350 |
| 3.40.50.720 | UDP-glucose 6-dehydrogenase 2
3.40.50.720-FF-285482
|
12
|
KIRP (2)
STAD (2)
UCEC (4)
BLCA (2)
COAD (2)
|
85.2 | 251.4 | 2.3E-76 | 1102 |
| 3.40.50.720 | Hydroxysteroid dehydrogenase like 2
3.40.50.720-FF-285086
|
2
|
BLCA (2)
|
90.0 | 392.2 | 1.5E-119 | 948 |
| 3.40.50.720 | NEDD8-activating enzyme E1 catalytic subunit
3.40.50.720-FF-285491
|
14
|
LUAD (2)
HNSC (2)
STAD (4)
UCEC (4)
ESCA (2)
|
81.6 | 304.7 | 8.0E-93 | 642 |
| 3.40.50.720 | Metalloreductase STEAP2
3.40.50.720-FF-288291
|
6
|
THCA (2)
LUAD (2)
SKCM (2)
|
96.6 | 237.8 | 8.5E-73 | 327 |
| 3.40.50.720 | Fatty acid synthase, putative
3.40.50.720-FF-285989
|
10
|
LIHC (2)
SKCM (4)
UCEC (2)
COAD (2)
|
89.4 | 328.3 | 3.4E-101 | 147 |
| 3.40.50.720 | Biliverdin reductase A
3.40.50.720-FF-286219
|
4
|
COAD (2)
UCEC (2)
|
70.8 | 202.7 | 5.8E-63 | 54 |
| 3.40.50.720 | Putative GDP-mannose 4,6-dehydratase
3.40.50.720-FF-286397
|
4
|
UCEC (2)
SKCM (2)
|
94.3 | 249.4 | 4.0E-75 | 2714 |
| 3.40.50.720 | Probable UDP-glucose 4-epimerase Gal10
3.40.50.720-FF-288574
|
6
|
STAD (2)
BLCA (2)
SKCM (2)
|
89.6 | 151.8 | 4.7E-45 | 12075 |
| 3.40.50.720 | NEDD8-activating enzyme E1 regulatory subunit
3.40.50.720-FF-287593
|
2
|
UCEC (2)
|
91.6 | 116.8 | 5.9E-36 | 513 |
| 3.40.50.720 | Malate dehydrogenase, cytoplasmic 1
3.40.50.720-FF-288686
|
2
|
SKCM (2)
|
91.0 | 167.9 | 1.8E-50 | 3748 |
| 3.40.50.720 | dTDP-glucose 4,6-dehydratase (RfbB)
3.40.50.720-FF-290267
|
2
|
UCEC (2)
|
84.2 | 155.8 | 4.1E-46 | 1907 |
| 3.40.50.720 | GDP-L-fucose synthetase, putative
3.40.50.720-FF-290700
|
2
|
PRAD (2)
|
84.3 | 183.1 | 5.5E-56 | 731 |
| 3.40.50.720 | Saccharopine dehydrogenase [NAD(+), L-lysine-forming]
3.40.50.720-FF-291583
|
10
|
SKCM (4)
UCEC (2)
LUAD (2)
HNSC (2)
|
85.1 | 133.1 | 2.5E-40 | 1095 |