| Superfamily | Functional Family | Mutation Events | Mutation Types | DOPS | Incl. Bitscore | Incl. Evalue | Seqs |
|---|---|---|---|---|---|---|---|
| 3.40.50.2000 | Glycogen [starch] synthase, muscle
3.40.50.2000-FF-6151
|
8
|
UCEC (2)
SKCM (2)
STAD (4)
|
79.0 | 280.4 | 1.4E-85 | 260 |
| 1.10.225.10 | Prosaposin variant
1.10.225.10-FF-1908
|
10
|
COAD (4)
KIRP (2)
SKCM (2)
UCEC (2)
|
71.8 | 157.9 | 1.8E-49 | 66 |
| 1.10.10.60 | Homeobox protein MSX-2, putative
1.10.10.60-FF-123451
|
4
|
COAD (4)
|
89.2 | 102.7 | 8.6E-32 | 9978 |
| 1.10.3260.10 | Ligase III, DNA, ATP-dependent
1.10.3260.10-FF-1297
|
8
|
STAD (2)
UCEC (4)
LGG (2)
|
93.2 | 256.8 | 1.6E-78 | 317 |
| 2.130.10.10 | Gem-associated protein 5
2.130.10.10-FF-25863
|
8
|
UCEC (4)
SKCM (2)
LIHC (2)
|
89.9 | 286.0 | 3.9E-88 | 101 |
| 1.10.340.30 | Putative 8-oxoguanine dna glycosylase
1.10.340.30-FF-7893
|
8
|
BLCA (2)
SKCM (4)
COAD (2)
|
82.2 | 113.0 | 1.6E-34 | 989 |
| 2.130.10.10 | U3 small nucleolar RNA-interacting protein 2
2.130.10.10-FF-103105
|
8
|
THCA (2)
UCEC (6)
|
91.6 | 459.8 | 3.1E-140 | 108 |
| 2.130.10.10 | F-box/WD repeat-containing protein 7
2.130.10.10-FF-102894
|
344
|
STAD (36)
BRCA (8)
CESC (34)
COAD (42)
UCEC (94)
UVM (2)
UCS (32)
BLCA (32)
HNSC (40)
READ (6)
LUSC (8)
ESCA (6)
GBM (2)
SKCM (2)
|
85.6 | 201.1 | 2.3E-62 | 329 |
| 2.130.10.10 | Probable pleiotropic regulator 1 (PLRG1)
2.130.10.10-FF-102602
|
10
|
CESC (2)
UCEC (4)
LUSC (2)
BLCA (2)
|
80.3 | 387.2 | 6.3E-118 | 1355 |
| 2.130.10.10 | WD repeat-containing protein 1
2.130.10.10-FF-102836
|
2
|
BLCA (2)
|
89.0 | 444.7 | 1.9E-135 | 328 |
| 2.130.10.10 | Actin-related protein 2/3 complex subunit 1A
2.130.10.10-FF-102847
|
6
|
LGG (2)
STAD (2)
COAD (2)
|
82.6 | 419.9 | 2.5E-127 | 1503 |
| 3.40.1080.10 | 3-oxoadipate CoA-transferase subunit A
3.40.1080.10-FF-5893
|
14
|
UCEC (2)
LUSC (2)
LUAD (2)
SKCM (2)
STAD (4)
COAD (2)
|
89.4 | 207.3 | 3.2E-62 | 11365 |
| 2.130.10.130 | Integrin alpha L
2.130.10.130-FF-8314
|
12
|
GBM (2)
BLCA (2)
LUAD (2)
STAD (4)
UCEC (2)
|
81.2 | 433.7 | 1.6E-132 | 52 |
| 3.30.420.110 | DNA mismatch repair protein msh3
3.30.420.110-FF-2654
|
4
|
LUAD (2)
UCEC (2)
|
85.9 | 174.8 | 1.5E-53 | 359 |
| 3.30.450.30 | Profilin
3.30.450.30-FF-55
|
2
|
COAD (2)
|
96.0 | 188.4 | 3.0E-58 | 885 |
| 3.30.450.30 | Coagulation factor XII-like protein
3.30.450.30-FF-2271
|
6
|
BLCA (2)
LUAD (2)
CESC (2)
|
91.6 | 173.9 | 5.2E-54 | 109 |
| 2.130.10.10 | DNA excision repair protein ERCC-8
2.130.10.10-FF-103743
|
4
|
HNSC (2)
UCEC (2)
|
94.1 | 256.9 | 2.0E-78 | 185 |
| 2.130.10.10 | Vpr (HIV-1) binding protein
2.130.10.10-FF-104005
|
4
|
COAD (2)
UCEC (2)
|
81.7 | 463.1 | 2.5E-141 | 139 |
| 2.40.30.10 | Elongation factor 1-alpha 2
2.40.30.10-FF-35770
|
4
|
LUSC (2)
SKCM (2)
|
87.1 | 144.0 | 4.7E-44 | 1238 |
| 3.30.50.10 | Glucocorticoid nuclear receptor variant 1
3.30.50.10-FF-4110
|
14
|
CESC (2)
COAD (2)
UCEC (4)
SKCM (4)
LUSC (2)
|
91.8 | 124.3 | 1.1E-38 | 651 |