| Superfamily | Functional Family | Mutation Events | Mutation Types | DOPS | Incl. Bitscore | Incl. Evalue | Seqs |
|---|---|---|---|---|---|---|---|
| 1.10.225.10 | Prosaposin variant
1.10.225.10-FF-1908
|
10
|
COAD (4)
KIRP (2)
SKCM (2)
UCEC (2)
|
71.8 | 157.9 | 1.8E-49 | 66 |
| 2.130.10.10 | Probable pleiotropic regulator 1 (PLRG1)
2.130.10.10-FF-102602
|
10
|
CESC (2)
UCEC (4)
LUSC (2)
BLCA (2)
|
80.3 | 387.2 | 6.3E-118 | 1355 |
| 2.130.10.10 | WD repeat-containing protein 1
2.130.10.10-FF-102836
|
2
|
BLCA (2)
|
89.0 | 444.7 | 1.9E-135 | 328 |
| 2.130.10.10 | Actin-related protein 2/3 complex subunit 1A
2.130.10.10-FF-102847
|
6
|
LGG (2)
STAD (2)
COAD (2)
|
82.6 | 419.9 | 2.5E-127 | 1503 |
| 3.40.1080.10 | 3-oxoadipate CoA-transferase subunit A
3.40.1080.10-FF-5893
|
14
|
UCEC (2)
LUSC (2)
LUAD (2)
SKCM (2)
STAD (4)
COAD (2)
|
89.4 | 207.3 | 3.2E-62 | 11365 |
| 3.40.350.10 | X-prolyl aminopeptidase 1, soluble
3.40.350.10-FF-6302
|
4
|
LGG (2)
HNSC (2)
|
88.6 | 185.8 | 2.4E-57 | 95 |
| 3.80.20.20 | Epidermal growth factor receptor
3.80.20.20-FF-3241
|
40
|
LGG (12)
GBM (22)
LUAD (4)
LUSC (2)
|
79.8 | 306.5 | 4.1E-94 | 116 |
| 3.80.20.20 | Tyrosine-protein kinase receptor
3.80.20.20-FF-3267
|
10
|
SKCM (6)
BLCA (2)
LUAD (2)
|
87.1 | 204.2 | 2.4E-62 | 427 |
| 3.30.1460.20 | Arp2/3 complex 20 kd subunit
3.30.1460.20-FF-442
|
2
|
BLCA (2)
|
89.5 | 245.1 | 6.6E-75 | 2363 |
| 3.30.1460.20 | Actin-related protein 2/3 complex subunit 2
3.30.1460.20-FF-450
|
8
|
UCEC (2)
COAD (2)
BRCA (2)
BLCA (2)
|
92.0 | 170.3 | 7.5E-52 | 1322 |
| 3.30.450.70 | Trafficking protein particle complex 4
3.30.450.70-FF-619
|
4
|
BLCA (2)
ESCA (2)
|
85.6 | 163.2 | 3.0E-50 | 541 |
| 3.30.450.70 | Trafficking protein particle complex 1
3.30.450.70-FF-621
|
2
|
UCEC (2)
|
75.0 | 182.6 | 1.7E-56 | 696 |
| 3.30.830.10 | Insulin-degrading enzyme isoform 4
3.30.830.10-FF-2593
|
8
|
UCEC (2)
SARC (2)
COAD (2)
PRAD (2)
|
73.2 | 366.3 | 3.1E-112 | 105 |
| 3.80.10.10 | Toll-like receptor 9
3.80.10.10-FF-105213
|
16
|
COAD (6)
STAD (2)
GBM (4)
SKCM (2)
PAAD (2)
|
76.9 | 473.5 | 3.2E-147 | 61 |
| 3.80.10.10 | Slit homolog 1 (Drosophila)
3.80.10.10-FF-105299
|
2
|
SKCM (2)
|
85.5 | 339.4 | 1.3E-103 | 367 |
| 3.80.10.10 | Leucine-rich repeat-containing protein 4B
3.80.10.10-FF-105374
|
2
|
UCEC (2)
|
82.5 | 115.4 | 2.0E-35 | 161 |
| 3.80.10.10 | Slit homolog 3 (Drosophila)
3.80.10.10-FF-105392
|
4
|
BLCA (2)
LUAD (2)
|
84.1 | 356.4 | 8.6E-109 | 317 |
| 3.80.10.10 | Toll like receptor 4
3.80.10.10-FF-106855
|
12
|
SKCM (4)
STAD (8)
|
88.1 | 474.1 | 2.0E-146 | 74 |
| 2.120.10.30 | Low-density lipoprotein receptor-related protein 6
2.120.10.30-FF-32876
|
12
|
COAD (4)
LIHC (2)
BLCA (2)
STAD (2)
BRCA (2)
|
92.4 | 339.1 | 2.9E-103 | 209 |
| 2.120.10.30 | Peptidyl-glycine alpha-amidating monooxygenase A
2.120.10.30-FF-32966
|
8
|
BRCA (2)
HNSC (2)
UCEC (2)
ESCA (2)
|
91.0 | 207.9 | 1.1E-63 | 128 |