| Superfamily | Functional Family | Mutation Events | Mutation Types | DOPS | Incl. Bitscore | Incl. Evalue | Seqs |
|---|---|---|---|---|---|---|---|
| 3.90.1010.10 | Iron-sulfur cluster assembly enzyme
3.90.1010.10-FF-2666
|
4
|
UCEC (4)
|
77.4 | 104.1 | 5.7E-31 | 2311 |
| 3.80.10.10 | Glucose-repressible alcohol dehydrogenase transcriptional effector
3.80.10.10-FF-106516
|
2
|
UCEC (2)
|
84.6 | 121.7 | 2.7E-37 | 1292 |
| 3.80.10.10 | Monocyte differentiation antigen CD14
3.80.10.10-FF-106624
|
12
|
STAD (4)
LUAD (2)
SKCM (4)
UCEC (2)
|
96.1 | 338.3 | 1.1E-103 | 180 |
| 3.80.10.10 | Follicle stimulating hormone receptor
3.80.10.10-FF-105163
|
6
|
STAD (2)
BRCA (2)
LUSC (2)
|
84.0 | 427.1 | 1.6E-130 | 68 |
| 3.80.10.10 | Toll-like receptor 9
3.80.10.10-FF-105213
|
16
|
COAD (6)
STAD (2)
GBM (4)
SKCM (2)
PAAD (2)
|
76.9 | 473.5 | 3.2E-147 | 61 |
| 3.80.10.10 | Slit homolog 1 (Drosophila)
3.80.10.10-FF-105299
|
2
|
SKCM (2)
|
85.5 | 339.4 | 1.3E-103 | 367 |
| 3.80.10.10 | Leucine-rich repeat-containing protein 4B
3.80.10.10-FF-105374
|
2
|
UCEC (2)
|
82.5 | 115.4 | 2.0E-35 | 161 |
| 3.80.10.10 | Slit homolog 3 (Drosophila)
3.80.10.10-FF-105392
|
4
|
BLCA (2)
LUAD (2)
|
84.1 | 356.4 | 8.6E-109 | 317 |
| 3.80.10.10 | Platelet glycoprotein Ib alpha
3.80.10.10-FF-106842
|
20
|
SKCM (8)
UCEC (2)
LIHC (2)
HNSC (2)
KIRC (2)
STAD (2)
COAD (2)
|
85.7 | 161.6 | 7.1E-50 | 84 |
| 3.80.10.10 | Toll like receptor 4
3.80.10.10-FF-106855
|
12
|
SKCM (4)
STAD (8)
|
88.1 | 474.1 | 2.0E-146 | 74 |
| 3.90.1530.10 | Putative sulfiredoxin
3.90.1530.10-FF-4952
|
2
|
COAD (2)
|
86.8 | 115.8 | 6.1E-36 | 337 |
| 1.25.40.90 | TOM1-like protein 1
1.25.40.90-FF-2915
|
4
|
LIHC (4)
|
73.3 | 221.7 | 1.3E-68 | 55 |
| 3.90.650.10 | Trifunctional purine biosynthetic protein adenosine-3
3.90.650.10-FF-8707
|
2
|
UCEC (2)
|
94.7 | 233.1 | 1.4E-71 | 162 |
| 1.25.40.90 | CID domain-containing protein 1
1.25.40.90-FF-3053
|
2
|
HNSC (2)
|
95.7 | 118.4 | 2.0E-36 | 290 |
| 2.120.10.30 | Low-density lipoprotein receptor-related protein 6
2.120.10.30-FF-32876
|
12
|
COAD (4)
LIHC (2)
BLCA (2)
STAD (2)
BRCA (2)
|
92.4 | 339.1 | 2.9E-103 | 209 |
| 2.40.50.140 | Translation initiation factor eIF-2 alpha subunit
2.40.50.140-FF-52963
|
4
|
HNSC (2)
STAD (2)
|
81.2 | 157.8 | 1.5E-48 | 2131 |
| 2.120.10.30 | Peptidyl-glycine alpha-amidating monooxygenase A
2.120.10.30-FF-32966
|
8
|
BRCA (2)
HNSC (2)
UCEC (2)
ESCA (2)
|
91.0 | 207.9 | 1.1E-63 | 128 |
| 2.40.50.140 | Single-stranded DNA-binding protein, mitochondrial
2.40.50.140-FF-9283
|
12
|
UCEC (8)
STAD (2)
LUAD (2)
|
75.3 | 215.1 | 1.5E-66 | 138 |
| 2.40.50.140 | 40S ribosomal protein S28
2.40.50.140-FF-66177
|
6
|
UCEC (2)
COAD (2)
PAAD (2)
|
97.8 | 115.5 | 4.4E-36 | 2437 |
| 2.70.50.40 | Protein unc-119 homolog A
2.70.50.40-FF-104
|
2
|
LUAD (2)
|
82.2 | 204.6 | 1.7E-62 | 796 |