| Superfamily | Functional Family | Mutation Events | Mutation Types | DOPS | Incl. Bitscore | Incl. Evalue | Seqs |
|---|---|---|---|---|---|---|---|
| 3.40.30.10 | Type II peroxiredoxin F
3.40.30.10-FF-79831
|
4
|
STAD (2)
BRCA (2)
|
95.0 | 134.0 | 3.3E-40 | 2877 |
| 3.40.30.10 | DnaJ subfamily C member 10
3.40.30.10-FF-79932
|
2
|
BLCA (2)
|
91.0 | 137.9 | 1.0E-42 | 116 |
| 3.40.50.2000 | Glycosyltransferase 1 domain-containing protein 1
3.40.50.2000-FF-97302
|
2
|
SKCM (2)
|
97.6 | 160.6 | 1.8E-49 | 144 |
| 1.10.225.10 | Prosaposin variant
1.10.225.10-FF-1908
|
10
|
COAD (4)
KIRP (2)
SKCM (2)
UCEC (2)
|
71.8 | 157.9 | 1.8E-49 | 66 |
| 2.130.10.10 | Gem-associated protein 5
2.130.10.10-FF-25863
|
8
|
UCEC (4)
SKCM (2)
LIHC (2)
|
89.9 | 286.0 | 3.9E-88 | 101 |
| 2.130.10.10 | Probable pleiotropic regulator 1 (PLRG1)
2.130.10.10-FF-102602
|
10
|
CESC (2)
UCEC (4)
LUSC (2)
BLCA (2)
|
80.3 | 387.2 | 6.3E-118 | 1355 |
| 2.130.10.10 | WD repeat-containing protein 1
2.130.10.10-FF-102836
|
2
|
BLCA (2)
|
89.0 | 444.7 | 1.9E-135 | 328 |
| 2.130.10.10 | Actin-related protein 2/3 complex subunit 1A
2.130.10.10-FF-102847
|
6
|
LGG (2)
STAD (2)
COAD (2)
|
82.6 | 419.9 | 2.5E-127 | 1503 |
| 2.130.10.10 | DNA excision repair protein ERCC-8
2.130.10.10-FF-103743
|
4
|
HNSC (2)
UCEC (2)
|
94.1 | 256.9 | 2.0E-78 | 185 |
| 2.130.10.10 | Vpr (HIV-1) binding protein
2.130.10.10-FF-104005
|
4
|
COAD (2)
UCEC (2)
|
81.7 | 463.1 | 2.5E-141 | 139 |
| 3.40.1080.10 | 3-oxoadipate CoA-transferase subunit A
3.40.1080.10-FF-5893
|
14
|
UCEC (2)
LUSC (2)
LUAD (2)
SKCM (2)
STAD (4)
COAD (2)
|
89.4 | 207.3 | 3.2E-62 | 11365 |
| 3.40.350.10 | X-prolyl aminopeptidase 1, soluble
3.40.350.10-FF-6302
|
4
|
LGG (2)
HNSC (2)
|
88.6 | 185.8 | 2.4E-57 | 95 |
| 3.80.20.20 | Epidermal growth factor receptor
3.80.20.20-FF-3241
|
40
|
LGG (12)
GBM (22)
LUAD (4)
LUSC (2)
|
79.8 | 306.5 | 4.1E-94 | 116 |
| 3.80.20.20 | Tyrosine-protein kinase receptor
3.80.20.20-FF-3267
|
10
|
SKCM (6)
BLCA (2)
LUAD (2)
|
87.1 | 204.2 | 2.4E-62 | 427 |
| 3.20.20.220 | Methylenetetrahydrofolate reductase 2
3.20.20.220-FF-3448
|
6
|
UCEC (6)
|
96.7 | 283.0 | 2.7E-85 | 3217 |
| 3.30.56.10 | Phenylalanine--tRNA ligase beta subunit
3.30.56.10-FF-2865
|
4
|
UCEC (2)
SKCM (2)
|
95.3 | 123.5 | 3.6E-38 | 311 |
| 3.30.830.10 | Insulin-degrading enzyme isoform 4
3.30.830.10-FF-2593
|
8
|
UCEC (2)
SARC (2)
COAD (2)
PRAD (2)
|
73.2 | 366.3 | 3.1E-112 | 105 |
| 3.40.50.10140 | Interleukin-1 receptor type 1
3.40.50.10140-FF-4407
|
2
|
SKCM (2)
|
94.2 | 123.8 | 2.0E-37 | 881 |
| 3.90.650.10 | Trifunctional purine biosynthetic protein adenosine-3
3.90.650.10-FF-8707
|
2
|
UCEC (2)
|
94.7 | 233.1 | 1.4E-71 | 162 |
| 2.120.10.30 | Low-density lipoprotein receptor-related protein 6
2.120.10.30-FF-32876
|
12
|
COAD (4)
LIHC (2)
BLCA (2)
STAD (2)
BRCA (2)
|
92.4 | 339.1 | 2.9E-103 | 209 |