| Superfamily | Functional Family | Mutation Events | Mutation Types | DOPS | Incl. Bitscore | Incl. Evalue | Seqs |
|---|---|---|---|---|---|---|---|
| 2.130.10.10 | Probable pleiotropic regulator 1 (PLRG1)
2.130.10.10-FF-102602
|
10
|
CESC (2)
UCEC (4)
LUSC (2)
BLCA (2)
|
80.3 | 387.2 | 6.3E-118 | 1355 |
| 2.130.10.10 | WD repeat-containing protein 1
2.130.10.10-FF-102836
|
2
|
BLCA (2)
|
89.0 | 444.7 | 1.9E-135 | 328 |
| 2.130.10.10 | Actin-related protein 2/3 complex subunit 1A
2.130.10.10-FF-102847
|
6
|
LGG (2)
STAD (2)
COAD (2)
|
82.6 | 419.9 | 2.5E-127 | 1503 |
| 2.40.30.10 | Elongation factor 1-alpha 2
2.40.30.10-FF-35770
|
4
|
LUSC (2)
SKCM (2)
|
87.1 | 144.0 | 4.7E-44 | 1238 |
| 3.30.50.10 | Glucocorticoid nuclear receptor variant 1
3.30.50.10-FF-4110
|
14
|
CESC (2)
COAD (2)
UCEC (4)
SKCM (4)
LUSC (2)
|
91.8 | 124.3 | 1.1E-38 | 651 |
| 3.40.1080.10 | 3-oxoadipate CoA-transferase subunit A
3.40.1080.10-FF-5893
|
14
|
UCEC (2)
LUSC (2)
LUAD (2)
SKCM (2)
STAD (4)
COAD (2)
|
89.4 | 207.3 | 3.2E-62 | 11365 |
| 3.40.350.10 | X-prolyl aminopeptidase 1, soluble
3.40.350.10-FF-6302
|
4
|
LGG (2)
HNSC (2)
|
88.6 | 185.8 | 2.4E-57 | 95 |
| 3.80.20.20 | Epidermal growth factor receptor
3.80.20.20-FF-3241
|
40
|
LGG (12)
GBM (22)
LUAD (4)
LUSC (2)
|
79.8 | 306.5 | 4.1E-94 | 116 |
| 3.80.20.20 | Tyrosine-protein kinase receptor
3.80.20.20-FF-3267
|
10
|
SKCM (6)
BLCA (2)
LUAD (2)
|
87.1 | 204.2 | 2.4E-62 | 427 |
| 3.20.20.220 | Methylenetetrahydrofolate reductase 2
3.20.20.220-FF-3448
|
6
|
UCEC (6)
|
96.7 | 283.0 | 2.7E-85 | 3217 |
| 3.30.450.70 | Trafficking protein particle complex 4
3.30.450.70-FF-619
|
4
|
BLCA (2)
ESCA (2)
|
85.6 | 163.2 | 3.0E-50 | 541 |
| 3.30.450.70 | Trafficking protein particle complex 1
3.30.450.70-FF-621
|
2
|
UCEC (2)
|
75.0 | 182.6 | 1.7E-56 | 696 |
| 3.30.830.10 | Cytochrome b-c1 complex subunit 2, mitochondrial
3.30.830.10-FF-16410
|
4
|
UCEC (2)
KICH (2)
|
87.5 | 357.0 | 1.6E-109 | 92 |
| 3.30.830.10 | Presequence protease, mitochondrial isoform 2
3.30.830.10-FF-16432
|
2
|
SKCM (2)
|
87.4 | 468.2 | 2.9E-144 | 109 |
| 3.80.10.10 | Toll-like receptor 9
3.80.10.10-FF-105213
|
16
|
COAD (6)
STAD (2)
GBM (4)
SKCM (2)
PAAD (2)
|
76.9 | 473.5 | 3.2E-147 | 61 |
| 3.80.10.10 | Slit homolog 1 (Drosophila)
3.80.10.10-FF-105299
|
2
|
SKCM (2)
|
85.5 | 339.4 | 1.3E-103 | 367 |
| 3.80.10.10 | Leucine-rich repeat-containing protein 4B
3.80.10.10-FF-105374
|
2
|
UCEC (2)
|
82.5 | 115.4 | 2.0E-35 | 161 |
| 3.80.10.10 | Slit homolog 3 (Drosophila)
3.80.10.10-FF-105392
|
4
|
BLCA (2)
LUAD (2)
|
84.1 | 356.4 | 8.6E-109 | 317 |
| 3.80.10.10 | Toll like receptor 4
3.80.10.10-FF-106855
|
12
|
SKCM (4)
STAD (8)
|
88.1 | 474.1 | 2.0E-146 | 74 |
| 2.120.10.30 | Low-density lipoprotein receptor-related protein 6
2.120.10.30-FF-32876
|
12
|
COAD (4)
LIHC (2)
BLCA (2)
STAD (2)
BRCA (2)
|
92.4 | 339.1 | 2.9E-103 | 209 |