| Superfamily | Functional Family | Mutation Events | Mutation Types | DOPS | Incl. Bitscore | Incl. Evalue | Seqs |
|---|---|---|---|---|---|---|---|
| 3.40.30.10 | Thioredoxin, mitochondrial
3.40.30.10-FF-79711
|
4
|
LIHC (2)
UCEC (2)
|
96.2 | 132.9 | 4.2E-41 | 274 |
| 3.40.30.10 | Selenoprotein W, 1
3.40.30.10-FF-79735
|
2
|
SKCM (2)
|
77.7 | 138.0 | 1.7E-43 | 57 |
| 3.40.50.2000 | Glycosyltransferase 1 domain-containing protein 1
3.40.50.2000-FF-97302
|
2
|
SKCM (2)
|
97.6 | 160.6 | 1.8E-49 | 144 |
| 2.130.10.10 | Gem-associated protein 5
2.130.10.10-FF-25863
|
8
|
UCEC (4)
SKCM (2)
LIHC (2)
|
89.9 | 286.0 | 3.9E-88 | 101 |
| 2.130.10.10 | F-box/WD repeat-containing protein 7
2.130.10.10-FF-102894
|
344
|
STAD (36)
BRCA (8)
CESC (34)
COAD (42)
UCEC (94)
UVM (2)
UCS (32)
BLCA (32)
HNSC (40)
READ (6)
LUSC (8)
ESCA (6)
GBM (2)
SKCM (2)
|
85.6 | 201.1 | 2.3E-62 | 329 |
| 2.130.10.10 | DNA excision repair protein ERCC-8
2.130.10.10-FF-103743
|
4
|
HNSC (2)
UCEC (2)
|
94.1 | 256.9 | 2.0E-78 | 185 |
| 2.130.10.10 | Vpr (HIV-1) binding protein
2.130.10.10-FF-104005
|
4
|
COAD (2)
UCEC (2)
|
81.7 | 463.1 | 2.5E-141 | 139 |
| 3.30.450.30 | Profilin
3.30.450.30-FF-55
|
2
|
COAD (2)
|
96.0 | 188.4 | 3.0E-58 | 885 |
| 3.30.450.30 | Coagulation factor XII-like protein
3.30.450.30-FF-2271
|
6
|
BLCA (2)
LUAD (2)
CESC (2)
|
91.6 | 173.9 | 5.2E-54 | 109 |
| 3.40.1080.10 | 3-oxoadipate CoA-transferase subunit A
3.40.1080.10-FF-5893
|
14
|
UCEC (2)
LUSC (2)
LUAD (2)
SKCM (2)
STAD (4)
COAD (2)
|
89.4 | 207.3 | 3.2E-62 | 11365 |
| 3.40.350.10 | X-prolyl aminopeptidase 1, soluble
3.40.350.10-FF-6302
|
4
|
LGG (2)
HNSC (2)
|
88.6 | 185.8 | 2.4E-57 | 95 |
| 3.40.720.10 | Ectonucleotide pyrophosphatase/phosphodiesterase family member 2
3.40.720.10-FF-18987
|
2
|
LUSC (2)
|
72.4 | 245.8 | 1.5E-75 | 121 |
| 3.40.720.10 | Ectonucleotide pyrophosphatase/phosphodiesterase family member 6
3.40.720.10-FF-19063
|
2
|
SKCM (2)
|
85.7 | 319.0 | 1.2E-97 | 106 |
| 3.40.720.10 | Mucin-desulfating sulfatase (N-acetylglucosamine-6-sulfatase)
3.40.720.10-FF-19128
|
2
|
STAD (2)
|
91.1 | 150.8 | 6.1E-46 | 3344 |
| 3.30.1460.20 | Arp2/3 complex 20 kd subunit
3.30.1460.20-FF-442
|
2
|
BLCA (2)
|
89.5 | 245.1 | 6.6E-75 | 2363 |
| 3.30.1460.20 | Actin-related protein 2/3 complex subunit 2
3.30.1460.20-FF-450
|
8
|
UCEC (2)
COAD (2)
BRCA (2)
BLCA (2)
|
92.0 | 170.3 | 7.5E-52 | 1322 |
| 3.30.450.70 | Trafficking protein particle complex 4
3.30.450.70-FF-619
|
4
|
BLCA (2)
ESCA (2)
|
85.6 | 163.2 | 3.0E-50 | 541 |
| 3.30.450.70 | Trafficking protein particle complex 1
3.30.450.70-FF-621
|
2
|
UCEC (2)
|
75.0 | 182.6 | 1.7E-56 | 696 |
| 3.30.830.10 | Cytochrome b-c1 complex subunit 2, mitochondrial
3.30.830.10-FF-16410
|
4
|
UCEC (2)
KICH (2)
|
87.5 | 357.0 | 1.6E-109 | 92 |
| 3.30.830.10 | Presequence protease, mitochondrial isoform 2
3.30.830.10-FF-16432
|
2
|
SKCM (2)
|
87.4 | 468.2 | 2.9E-144 | 109 |