| Superfamily | Functional Family | Mutation Events | Mutation Types | DOPS | Incl. Bitscore | Incl. Evalue | Seqs |
|---|---|---|---|---|---|---|---|
| 3.30.200.20 | Serine/threonine-protein kinase MRCK beta
3.30.200.20-FF-806
|
10
|
HNSC (2)
SKCM (4)
CESC (2)
LUSC (2)
|
73.4 | 180.8 | 5.2E-57 | 217 |
| 3.30.200.20 | Rho-associated protein kinase 2
3.30.200.20-FF-1059
|
8
|
UCEC (8)
|
91.3 | 173.0 | 4.3E-55 | 390 |
| 3.30.200.20 | Receptor-type tyrosine-protein kinase FLT3
3.30.200.20-FF-1539
|
10
|
SKCM (8)
CESC (2)
|
80.8 | 215.4 | 9.6E-68 | 107 |
| 3.30.200.20 | Receptor protein serine/threonine kinase
3.30.200.20-FF-4418
|
12
|
COAD (4)
BRCA (2)
KIRC (2)
UCEC (4)
|
85.3 | 163.0 | 7.3E-52 | 1292 |
| 3.30.200.20 | Serine/threonine-protein kinase MRCK alpha
3.30.200.20-FF-4717
|
2
|
BRCA (2)
|
85.9 | 229.3 | 7.0E-73 | 301 |
| 3.30.200.20 | Cyclin-dependent protein kinase PHO85
3.30.200.20-FF-5241
|
6
|
STAD (2)
BLCA (2)
UCEC (2)
|
88.6 | 106.1 | 4.2E-34 | 708 |
| 3.30.200.20 | Calcium/calmodulin-dependent protein kinase type IV
3.30.200.20-FF-7644
|
12
|
SKCM (2)
BLCA (2)
STAD (2)
COAD (2)
UCEC (4)
|
71.0 | 164.7 | 8.4E-53 | 49 |
| 3.30.60.20 | Kinase C alpha type
3.30.60.20-FF-92
|
2
|
SKCM (2)
|
78.9 | 137.1 | 5.6E-43 | 305 |
| 3.60.21.10 | Metallophosphoesterase domain-containing protein 1
3.60.21.10-FF-29492
|
2
|
UCEC (2)
|
92.1 | 262.1 | 3.5E-80 | 1619 |
| 3.60.21.10 | Bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase protein
3.60.21.10-FF-29502
|
2
|
LIHC (2)
|
96.5 | 167.3 | 6.6E-50 | 3123 |
| 1.10.555.10 | Rho GTPase-activating protein 5
1.10.555.10-FF-3898
|
2
|
UCEC (2)
|
86.6 | 260.5 | 8.0E-80 | 195 |
| 1.10.555.10 | Rho GTPase-activating protein 20
1.10.555.10-FF-3997
|
4
|
SKCM (2)
COAD (2)
|
79.9 | 177.5 | 3.0E-54 | 265 |
| 2.60.40.630 | Signal transducer and transcription activator
2.60.40.630-FF-150
|
6
|
READ (2)
STAD (2)
PRAD (2)
|
88.2 | 141.6 | 2.9E-43 | 389 |
| 3.40.50.10490 | Glucose-6-phosphate isomerase 1
3.40.50.10490-FF-21115
|
2
|
COAD (2)
|
96.0 | 179.1 | 1.2E-54 | 2687 |
| 3.40.50.920 | Transketolase-like protein 1 isoform a
3.40.50.920-FF-11795
|
2
|
UCEC (2)
|
83.6 | 222.3 | 1.2E-68 | 184 |
| 2.102.10.10 | Cytochrome b-c1 complex subunit Rieske
2.102.10.10-FF-8165
|
4
|
UCEC (2)
PAAD (2)
|
85.3 | 169.4 | 2.0E-51 | 2036 |
| 3.40.30.10 | Type II peroxiredoxin F
3.40.30.10-FF-79831
|
4
|
STAD (2)
BRCA (2)
|
95.0 | 134.0 | 3.3E-40 | 2877 |
| 3.40.30.10 | DnaJ subfamily C member 10
3.40.30.10-FF-79932
|
2
|
BLCA (2)
|
91.0 | 137.9 | 1.0E-42 | 116 |
| 1.10.3260.10 | Ligase III, DNA, ATP-dependent
1.10.3260.10-FF-1297
|
8
|
STAD (2)
UCEC (4)
LGG (2)
|
93.2 | 256.8 | 1.6E-78 | 317 |
| 1.10.340.30 | Putative 8-oxoguanine dna glycosylase
1.10.340.30-FF-7893
|
8
|
BLCA (2)
SKCM (4)
COAD (2)
|
82.2 | 113.0 | 1.6E-34 | 989 |