| Superfamily | Functional Family | Mutation Events | Mutation Types | DOPS | Incl. Bitscore | Incl. Evalue | Seqs |
|---|---|---|---|---|---|---|---|
| 3.40.1080.10 | 3-oxoadipate CoA-transferase subunit A
3.40.1080.10-FF-5893
|
14
|
UCEC (2)
LUSC (2)
LUAD (2)
SKCM (2)
STAD (4)
COAD (2)
|
89.4 | 207.3 | 3.2E-62 | 11365 |
| 3.40.720.10 | Ectonucleotide pyrophosphatase/phosphodiesterase family member 2
3.40.720.10-FF-18987
|
2
|
LUSC (2)
|
72.4 | 245.8 | 1.5E-75 | 121 |
| 3.40.350.10 | X-prolyl aminopeptidase 1, soluble
3.40.350.10-FF-6302
|
4
|
LGG (2)
HNSC (2)
|
88.6 | 185.8 | 2.4E-57 | 95 |
| 3.40.470.10 | G/U mismatch-specific DNA glycosylase
3.40.470.10-FF-4994
|
10
|
SKCM (8)
UCEC (2)
|
83.8 | 165.6 | 2.0E-50 | 35007 |
| 3.40.470.10 | Uracil-DNA glycosylase 1
3.40.470.10-FF-4996
|
2
|
LUAD (2)
|
86.0 | 166.4 | 2.3E-49 | 2248 |
| 3.40.720.10 | Ectonucleotide pyrophosphatase/phosphodiesterase family member 6
3.40.720.10-FF-19063
|
2
|
SKCM (2)
|
85.7 | 319.0 | 1.2E-97 | 106 |
| 3.80.20.20 | Epidermal growth factor receptor
3.80.20.20-FF-3241
|
40
|
LGG (12)
GBM (22)
LUAD (4)
LUSC (2)
|
79.8 | 306.5 | 4.1E-94 | 116 |
| 3.80.20.20 | Tyrosine-protein kinase receptor
3.80.20.20-FF-3267
|
10
|
SKCM (6)
BLCA (2)
LUAD (2)
|
87.1 | 204.2 | 2.4E-62 | 427 |
| 3.30.56.10 | Phenylalanine--tRNA ligase beta subunit
3.30.56.10-FF-2865
|
4
|
UCEC (2)
SKCM (2)
|
95.3 | 123.5 | 3.6E-38 | 311 |
| 2.60.120.620 | Prolyl 3-hydroxylase OGFOD1
2.60.120.620-FF-7066
|
6
|
UCEC (4)
STAD (2)
|
85.8 | 264.8 | 2.3E-82 | 107 |
| 3.30.450.70 | Trafficking protein particle complex 4
3.30.450.70-FF-619
|
4
|
BLCA (2)
ESCA (2)
|
85.6 | 163.2 | 3.0E-50 | 541 |
| 3.30.450.70 | Trafficking protein particle complex 1
3.30.450.70-FF-621
|
2
|
UCEC (2)
|
75.0 | 182.6 | 1.7E-56 | 696 |
| 3.20.20.220 | Methylenetetrahydrofolate reductase 2
3.20.20.220-FF-3448
|
6
|
UCEC (6)
|
96.7 | 283.0 | 2.7E-85 | 3217 |
| 3.30.1460.20 | Arp2/3 complex 20 kd subunit
3.30.1460.20-FF-442
|
2
|
BLCA (2)
|
89.5 | 245.1 | 6.6E-75 | 2363 |
| 3.30.1460.20 | Actin-related protein 2/3 complex subunit 2
3.30.1460.20-FF-450
|
8
|
UCEC (2)
COAD (2)
BRCA (2)
BLCA (2)
|
92.0 | 170.3 | 7.5E-52 | 1322 |
| 3.30.830.10 | Insulin-degrading enzyme isoform 4
3.30.830.10-FF-2593
|
8
|
UCEC (2)
SARC (2)
COAD (2)
PRAD (2)
|
73.2 | 366.3 | 3.1E-112 | 105 |
| 3.80.10.10 | Follicle stimulating hormone receptor
3.80.10.10-FF-105163
|
6
|
STAD (2)
BRCA (2)
LUSC (2)
|
84.0 | 427.1 | 1.6E-130 | 68 |
| 3.30.830.10 | Cytochrome b-c1 complex subunit 2, mitochondrial
3.30.830.10-FF-16410
|
4
|
UCEC (2)
KICH (2)
|
87.5 | 357.0 | 1.6E-109 | 92 |
| 3.30.830.10 | Presequence protease, mitochondrial isoform 2
3.30.830.10-FF-16432
|
2
|
SKCM (2)
|
87.4 | 468.2 | 2.9E-144 | 109 |
| 3.40.50.10140 | Interleukin-1 receptor type 1
3.40.50.10140-FF-4407
|
2
|
SKCM (2)
|
94.2 | 123.8 | 2.0E-37 | 881 |