| Superfamily | Functional Family | Mutation Events | Mutation Types | DOPS | Incl. Bitscore | Incl. Evalue | Seqs |
|---|---|---|---|---|---|---|---|
| 1.25.40.20 | Cyclin-dependent kinase inhibitor 2A
1.25.40.20-FF-62346
|
130
|
BLCA (10)
CESC (2)
ESCA (8)
LIHC (10)
PAAD (10)
HNSC (20)
LUSC (36)
SKCM (18)
LUAD (10)
CHOL (2)
STAD (4)
|
88.4 | 141.0 | 8.4E-44 | 112 |
| 1.25.40.20 | Arf GTPase-activating domain-containing protein
1.25.40.20-FF-62579
|
4
|
HNSC (2)
CESC (2)
|
90.5 | 141.1 | 3.0E-43 | 309 |
| 2.120.10.10 | Sialidase 1 (Lysosomal sialidase)
2.120.10.10-FF-4481
|
4
|
LUSC (2)
UCEC (2)
|
89.2 | 207.3 | 5.9E-63 | 361 |
| 3.30.450.20 | Period circadian protein homolog 1
3.30.450.20-FF-87883
|
8
|
SKCM (4)
UCEC (4)
|
81.9 | 229.9 | 1.5E-71 | 353 |
| 3.60.110.10 | Vascular non-inflammatory molecule 3
3.60.110.10-FF-8179
|
6
|
UCEC (4)
SKCM (2)
|
91.9 | 293.2 | 4.6E-89 | 434 |
| 3.90.770.10 | 3-hydroxy-3-methylglutaryl coenzyme A reductase
3.90.770.10-FF-1368
|
8
|
BLCA (2)
UCEC (2)
STAD (2)
COAD (2)
|
92.4 | 212.6 | 2.0E-64 | 1032 |
| 1.20.1250.10 | Growth hormone 1 variant 2
1.20.1250.10-FF-147
|
2
|
SKCM (2)
|
98.0 | 217.0 | 1.4E-66 | 255 |
| 1.20.1250.10 | Viral interleukin-10 homolog
1.20.1250.10-FF-8013
|
14
|
STAD (2)
ESCA (2)
UCEC (4)
READ (2)
CESC (2)
LUSC (2)
|
83.4 | 240.3 | 2.8E-74 | 149 |
| 1.20.1250.10 | Interleukin-19
1.20.1250.10-FF-8020
|
2
|
BLCA (2)
|
71.1 | 282.6 | 9.8E-88 | 31 |
| 1.20.1250.10 | Interleukin-6
1.20.1250.10-FF-8045
|
10
|
DLBC (2)
COAD (4)
LIHC (2)
READ (2)
|
96.7 | 187.7 | 4.7E-58 | 89 |
| 1.20.1250.20 | Solute carrier family 2 , member 5
1.20.1250.20-FF-179185
|
2
|
COAD (2)
|
90.2 | 339.8 | 1.5E-105 | 147 |
| 3.30.70.1230 | Guanylate cyclase soluble subunit beta-1
3.30.70.1230-FF-5698
|
6
|
KIRC (2)
SKCM (2)
UCEC (2)
|
78.7 | 304.7 | 1.9E-93 | 238 |
| 3.30.70.1230 | Adenylate cyclase type 2
3.30.70.1230-FF-5743
|
2
|
LUAD (2)
|
82.2 | 223.0 | 2.4E-67 | 988 |
| 3.40.1380.10 | ATP synthase subunit gamma
3.40.1380.10-FF-2296
|
4
|
LUSC (2)
GBM (2)
|
96.6 | 128.9 | 2.7E-39 | 689 |
| 3.90.1200.10 | Probable choline kinase 1
3.90.1200.10-FF-17534
|
12
|
LUSC (2)
CESC (2)
UCEC (4)
BLCA (2)
DLBC (2)
|
84.3 | 115.7 | 9.6E-35 | 1303 |
| 3.90.1200.10 | Acyl-CoA dehydrogenase family member 10
3.90.1200.10-FF-17576
|
4
|
HNSC (2)
SKCM (2)
|
88.6 | 131.8 | 1.2E-39 | 1378 |
| 1.20.120.310 | Sulfhydryl oxidase 1
1.20.120.310-FF-670
|
8
|
STAD (2)
SKCM (2)
LUAD (4)
|
80.0 | 160.8 | 3.6E-50 | 403 |
| 2.60.40.1530 | Integrin alpha-V isoform 1-like protein
2.60.40.1530-FF-812
|
2
|
GBM (2)
|
78.7 | 341.9 | 8.2E-105 | 91 |
| 2.60.40.1530 | PREDICTED: integrin, alpha D variant
2.60.40.1530-FF-818
|
8
|
COAD (4)
UCEC (4)
|
77.5 | 318.4 | 1.9E-98 | 30 |
| 3.30.200.20 | Aurora kinase A
3.30.200.20-FF-127
|
4
|
BLCA (2)
UCEC (2)
|
82.2 | 146.7 | 9.5E-47 | 1027 |