| Superfamily | Functional Family | Mutation Events | Mutation Types | DOPS | Incl. Bitscore | Incl. Evalue | Seqs |
|---|---|---|---|---|---|---|---|
| 3.30.200.20 | Protein kinase C alpha type
3.30.200.20-FF-64541
|
2
|
SKCM (2)
|
79.4 | 188.4 | 9.4E-60 | 442 |
| 3.30.200.20 | Cyclin-dependent kinase 8
3.30.200.20-FF-64559
|
8
|
GBM (2)
HNSC (2)
UCEC (2)
LUAD (2)
|
89.8 | 126.0 | 9.3E-41 | 480 |
| 3.30.470.30 | DNA ligase 4
3.30.470.30-FF-5567
|
2
|
LUSC (2)
|
89.0 | 267.4 | 1.7E-82 | 912 |
| 3.30.60.20 | Kinase C alpha type
3.30.60.20-FF-92
|
2
|
SKCM (2)
|
78.9 | 137.1 | 5.6E-43 | 305 |
| 1.10.555.10 | Rho GTPase-activating protein 20
1.10.555.10-FF-3997
|
4
|
SKCM (2)
COAD (2)
|
79.9 | 177.5 | 3.0E-54 | 265 |
| 3.10.110.10 | Ubiquitin-conjugating enzyme E2 R2
3.10.110.10-FF-5883
|
20
|
DLBC (2)
GBM (4)
BRCA (2)
STAD (2)
CESC (2)
UCEC (6)
LUSC (2)
|
81.0 | 252.1 | 3.0E-77 | 1025 |
| 1.10.580.10 | Probable citrate synthase, mitochondrial
1.10.580.10-FF-132
|
4
|
LIHC (2)
COAD (2)
|
90.5 | 123.1 | 6.5E-37 | 1581 |
| 2.60.40.630 | Signal transducer and transcription activator
2.60.40.630-FF-150
|
6
|
READ (2)
STAD (2)
PRAD (2)
|
88.2 | 141.6 | 2.9E-43 | 389 |
| 3.10.110.10 | Eukaryotic translation initiation factor 2-alpha kinase 4
3.10.110.10-FF-5934
|
4
|
UCEC (2)
LIHC (2)
|
73.5 | 210.6 | 2.2E-65 | 43 |
| 2.170.210.10 | Non-homologous end-joining factor 1
2.170.210.10-FF-199
|
10
|
UCEC (8)
CESC (2)
|
90.3 | 125.3 | 5.6E-39 | 74 |
| 2.20.160.10 | Titin-cap
2.20.160.10-FF-13
|
4
|
BRCA (2)
PRAD (2)
|
79.1 | 129.0 | 1.3E-40 | 50 |
| 3.10.110.10 | Ubiquitin-conjugating enzyme E2 S
3.10.110.10-FF-5976
|
8
|
STAD (2)
UCEC (4)
SKCM (2)
|
81.2 | 260.3 | 3.5E-80 | 279 |
| 3.10.110.10 | Ubiquitin-conjugating enzyme 27, E2
3.10.110.10-FF-6007
|
6
|
UCEC (2)
READ (4)
|
72.1 | 163.5 | 8.4E-50 | 3065 |
| 3.10.110.10 | Ubiquitin-conjugating enzyme E2 2
3.10.110.10-FF-6050
|
10
|
UCEC (2)
STAD (2)
BLCA (2)
SKCM (4)
|
72.3 | 103.1 | 1.0E-30 | 7541 |
| 3.10.320.10 | MHC class II antigen
3.10.320.10-FF-3768
|
6
|
UCEC (4)
CESC (2)
|
86.1 | 156.5 | 6.6E-49 | 121 |
| 3.30.1050.10 | Peroxisomal multifunctional enzyme type 2
3.30.1050.10-FF-2018
|
14
|
LUSC (2)
UCEC (6)
PAAD (2)
SKCM (2)
BLCA (2)
|
83.6 | 171.5 | 3.3E-53 | 93 |
| 3.10.110.10 | RWD domain-containing protein 3
3.10.110.10-FF-6071
|
8
|
SKCM (4)
LUSC (2)
UCEC (2)
|
84.4 | 148.4 | 1.5E-46 | 41 |
| 3.40.50.10490 | Glucose-6-phosphate isomerase 1
3.40.50.10490-FF-21115
|
2
|
COAD (2)
|
96.0 | 179.1 | 1.2E-54 | 2687 |
| 3.40.50.1000 | Phosphoserine phosphatase, isoform CRA_b
3.40.50.1000-FF-57520
|
16
|
GBM (2)
SKCM (4)
CESC (2)
BLCA (2)
UCEC (4)
HNSC (2)
|
83.8 | 195.5 | 3.8E-60 | 252 |
| 3.40.50.1000 | Translocase of inner mitochondrial membrane 50-related
3.40.50.1000-FF-57598
|
2
|
STAD (2)
|
86.2 | 213.9 | 4.9E-65 | 1213 |