| Superfamily | Functional Family | Mutation Events | Mutation Types | DOPS | Incl. Bitscore | Incl. Evalue | Seqs |
|---|---|---|---|---|---|---|---|
| 3.40.50.1000 | Phosphoserine phosphatase, isoform CRA_b
3.40.50.1000-FF-57520
|
16
|
GBM (2)
SKCM (4)
CESC (2)
BLCA (2)
UCEC (4)
HNSC (2)
|
83.8 | 195.5 | 3.8E-60 | 252 |
| 3.40.50.1000 | Translocase of inner mitochondrial membrane 50-related
3.40.50.1000-FF-57598
|
2
|
STAD (2)
|
86.2 | 213.9 | 4.9E-65 | 1213 |
| 3.40.50.1000 | Enolase-phosphatase E1, putative
3.40.50.1000-FF-57698
|
2
|
SKCM (2)
|
91.7 | 131.0 | 3.4E-40 | 497 |
| 3.40.50.920 | Transketolase-like protein 1 isoform a
3.40.50.920-FF-11795
|
2
|
UCEC (2)
|
83.6 | 222.3 | 1.2E-68 | 184 |
| 2.102.10.10 | Cytochrome b-c1 complex subunit Rieske
2.102.10.10-FF-8165
|
4
|
UCEC (2)
PAAD (2)
|
85.3 | 169.4 | 2.0E-51 | 2036 |
| 3.40.30.10 | Type II peroxiredoxin F
3.40.30.10-FF-79831
|
4
|
STAD (2)
BRCA (2)
|
95.0 | 134.0 | 3.3E-40 | 2877 |
| 3.40.30.10 | DnaJ subfamily C member 10
3.40.30.10-FF-79932
|
2
|
BLCA (2)
|
91.0 | 137.9 | 1.0E-42 | 116 |
| 1.10.225.10 | Prosaposin variant
1.10.225.10-FF-1908
|
10
|
COAD (4)
KIRP (2)
SKCM (2)
UCEC (2)
|
71.8 | 157.9 | 1.8E-49 | 66 |
| 2.130.10.10 | Gem-associated protein 5
2.130.10.10-FF-25863
|
8
|
UCEC (4)
SKCM (2)
LIHC (2)
|
89.9 | 286.0 | 3.9E-88 | 101 |
| 2.130.10.10 | F-box/WD repeat-containing protein 7
2.130.10.10-FF-102894
|
344
|
STAD (36)
BRCA (8)
CESC (34)
COAD (42)
UCEC (94)
UVM (2)
UCS (32)
BLCA (32)
HNSC (40)
READ (6)
LUSC (8)
ESCA (6)
GBM (2)
SKCM (2)
|
85.6 | 201.1 | 2.3E-62 | 329 |
| 2.130.10.10 | DNA excision repair protein ERCC-8
2.130.10.10-FF-103743
|
4
|
HNSC (2)
UCEC (2)
|
94.1 | 256.9 | 2.0E-78 | 185 |
| 2.130.10.10 | Vpr (HIV-1) binding protein
2.130.10.10-FF-104005
|
4
|
COAD (2)
UCEC (2)
|
81.7 | 463.1 | 2.5E-141 | 139 |
| 3.30.420.110 | DNA mismatch repair protein msh3
3.30.420.110-FF-2654
|
4
|
LUAD (2)
UCEC (2)
|
85.9 | 174.8 | 1.5E-53 | 359 |
| 3.30.50.10 | Glucocorticoid nuclear receptor variant 1
3.30.50.10-FF-4110
|
14
|
CESC (2)
COAD (2)
UCEC (4)
SKCM (4)
LUSC (2)
|
91.8 | 124.3 | 1.1E-38 | 651 |
| 3.40.1080.10 | 3-oxoadipate CoA-transferase subunit A
3.40.1080.10-FF-5893
|
14
|
UCEC (2)
LUSC (2)
LUAD (2)
SKCM (2)
STAD (4)
COAD (2)
|
89.4 | 207.3 | 3.2E-62 | 11365 |
| 3.40.350.10 | X-prolyl aminopeptidase 1, soluble
3.40.350.10-FF-6302
|
4
|
LGG (2)
HNSC (2)
|
88.6 | 185.8 | 2.4E-57 | 95 |
| 3.80.20.20 | Epidermal growth factor receptor
3.80.20.20-FF-3241
|
40
|
LGG (12)
GBM (22)
LUAD (4)
LUSC (2)
|
79.8 | 306.5 | 4.1E-94 | 116 |
| 3.80.20.20 | Tyrosine-protein kinase receptor
3.80.20.20-FF-3267
|
10
|
SKCM (6)
BLCA (2)
LUAD (2)
|
87.1 | 204.2 | 2.4E-62 | 427 |
| 3.30.1460.20 | Arp2/3 complex 20 kd subunit
3.30.1460.20-FF-442
|
2
|
BLCA (2)
|
89.5 | 245.1 | 6.6E-75 | 2363 |
| 3.30.1460.20 | Actin-related protein 2/3 complex subunit 2
3.30.1460.20-FF-450
|
8
|
UCEC (2)
COAD (2)
BRCA (2)
BLCA (2)
|
92.0 | 170.3 | 7.5E-52 | 1322 |