| Superfamily | Functional Family | Mutation Events | Mutation Types | DOPS | Incl. Bitscore | Incl. Evalue | Seqs |
|---|---|---|---|---|---|---|---|
| 3.80.10.10 | Slit homolog 1 (Drosophila)
3.80.10.10-FF-105299
|
2
|
SKCM (2)
|
85.5 | 339.4 | 1.3E-103 | 367 |
| 3.80.10.10 | Leucine-rich repeat-containing protein 4B
3.80.10.10-FF-105374
|
2
|
UCEC (2)
|
82.5 | 115.4 | 2.0E-35 | 161 |
| 3.80.10.10 | Slit homolog 3 (Drosophila)
3.80.10.10-FF-105392
|
4
|
BLCA (2)
LUAD (2)
|
84.1 | 356.4 | 8.6E-109 | 317 |
| 3.80.10.10 | Toll like receptor 4
3.80.10.10-FF-106855
|
12
|
SKCM (4)
STAD (8)
|
88.1 | 474.1 | 2.0E-146 | 74 |
| 2.120.10.30 | Low-density lipoprotein receptor-related protein 6
2.120.10.30-FF-32876
|
12
|
COAD (4)
LIHC (2)
BLCA (2)
STAD (2)
BRCA (2)
|
92.4 | 339.1 | 2.9E-103 | 209 |
| 2.120.10.30 | Peptidyl-glycine alpha-amidating monooxygenase A
2.120.10.30-FF-32966
|
8
|
BRCA (2)
HNSC (2)
UCEC (2)
ESCA (2)
|
91.0 | 207.9 | 1.1E-63 | 128 |
| 3.30.200.20 | Tyrosine-protein kinase HCK
3.30.200.20-FF-3754
|
6
|
UCEC (2)
SKCM (4)
|
72.3 | 161.3 | 2.8E-51 | 116 |
| 3.30.200.20 | Receptor tyrosine-protein kinase erbB-4
3.30.200.20-FF-3940
|
2
|
SKCM (2)
|
98.2 | 98.9 | 1.2E-31 | 272 |
| 3.30.200.20 | Phosphorylase kinase catalytic subunit PHKG2 homolog protein
3.30.200.20-FF-66370
|
2
|
UCEC (2)
|
87.0 | 144.5 | 4.1E-46 | 155 |
| 3.30.60.20 | Kinase C alpha type
3.30.60.20-FF-92
|
2
|
SKCM (2)
|
78.9 | 137.1 | 5.6E-43 | 305 |
| 2.170.210.10 | Non-homologous end-joining factor 1
2.170.210.10-FF-199
|
10
|
UCEC (8)
CESC (2)
|
90.3 | 125.3 | 5.6E-39 | 74 |
| 2.20.160.10 | Titin-cap
2.20.160.10-FF-13
|
4
|
BRCA (2)
PRAD (2)
|
79.1 | 129.0 | 1.3E-40 | 50 |
| 3.40.50.1460 | Caspase-6
3.40.50.1460-FF-5819
|
4
|
UCEC (2)
STAD (2)
|
81.2 | 334.8 | 1.5E-104 | 62 |
| 3.40.50.1460 | Caspase 9, isoform CRA_a
3.40.50.1460-FF-5857
|
10
|
ESCA (2)
UCEC (6)
CESC (2)
|
82.7 | 297.3 | 1.8E-92 | 57 |
| 3.40.50.1460 | Vacuolar-processing enzyme beta-isozyme 1
3.40.50.1460-FF-5885
|
6
|
COAD (4)
SARC (2)
|
87.7 | 299.8 | 5.6E-91 | 561 |
| 3.40.50.1460 | Caspase-3
3.40.50.1460-FF-5889
|
4
|
SKCM (2)
UCEC (2)
|
92.2 | 193.1 | 2.5E-60 | 212 |
| 2.102.10.10 | Cytochrome b-c1 complex subunit Rieske
2.102.10.10-FF-8165
|
4
|
UCEC (2)
PAAD (2)
|
85.3 | 169.4 | 2.0E-51 | 2036 |
| 3.40.30.10 | Type II peroxiredoxin F
3.40.30.10-FF-79831
|
4
|
STAD (2)
BRCA (2)
|
95.0 | 134.0 | 3.3E-40 | 2877 |
| 3.40.30.10 | DnaJ subfamily C member 10
3.40.30.10-FF-79932
|
2
|
BLCA (2)
|
91.0 | 137.9 | 1.0E-42 | 116 |
| 1.10.10.60 | Homeobox protein MSX-2, putative
1.10.10.60-FF-123451
|
4
|
COAD (4)
|
89.2 | 102.7 | 8.6E-32 | 9978 |