| Superfamily | Functional Family | Mutation Events | Mutation Types | DOPS | Incl. Bitscore | Incl. Evalue | Seqs |
|---|---|---|---|---|---|---|---|
| 3.30.70.1230 | Adenylate cyclase type 2
3.30.70.1230-FF-5743
|
2
|
LUAD (2)
|
82.2 | 223.0 | 2.4E-67 | 988 |
| 3.40.50.1400 | Ferrochelatase (Predicted), isoform CRA_a
3.40.50.1400-FF-5529
|
12
|
GBM (2)
UCEC (6)
SKCM (4)
|
95.2 | 143.9 | 3.2E-43 | 1273 |
| 3.90.1200.10 | Probable choline kinase 1
3.90.1200.10-FF-17534
|
12
|
LUSC (2)
CESC (2)
UCEC (4)
BLCA (2)
DLBC (2)
|
84.3 | 115.7 | 9.6E-35 | 1303 |
| 3.90.1200.10 | Acyl-CoA dehydrogenase family member 10
3.90.1200.10-FF-17576
|
4
|
HNSC (2)
SKCM (2)
|
88.6 | 131.8 | 1.2E-39 | 1378 |
| 1.10.400.10 | Guanine nucleotide-binding protein G(S) subunit alpha
1.10.400.10-FF-1404
|
70
|
ACC (2)
LUAD (10)
ESCA (4)
PAAD (14)
SKCM (4)
COAD (10)
READ (2)
LIHC (10)
STAD (8)
CESC (4)
UCEC (2)
|
85.7 | 150.4 | 3.4E-46 | 837 |
| 1.10.400.10 | Guanine nucleotide-binding protein subunit alpha-11
1.10.400.10-FF-1411
|
22
|
UCEC (4)
LUAD (2)
SKCM (2)
COAD (2)
UVM (6)
BLCA (2)
LGG (2)
GBM (2)
|
79.1 | 122.5 | 2.5E-37 | 1794 |
| 1.20.5.50 | Fibrinogen alpha chain-like protein
1.20.5.50-FF-13772
|
10
|
SKCM (2)
LUSC (2)
READ (2)
UCEC (4)
|
70.0 | 369.9 | 3.9E-114 | 35 |
| 1.20.120.310 | Sulfhydryl oxidase 1
1.20.120.310-FF-670
|
8
|
STAD (2)
SKCM (2)
LUAD (4)
|
80.0 | 160.8 | 3.6E-50 | 403 |
| 3.30.200.20 | Aurora kinase A
3.30.200.20-FF-127
|
4
|
BLCA (2)
UCEC (2)
|
82.2 | 146.7 | 9.5E-47 | 1027 |
| 2.60.40.1530 | Integrin alpha-V isoform 1-like protein
2.60.40.1530-FF-812
|
2
|
GBM (2)
|
78.7 | 341.9 | 8.2E-105 | 91 |
| 2.60.40.1530 | PREDICTED: integrin, alpha D variant
2.60.40.1530-FF-818
|
8
|
COAD (4)
UCEC (4)
|
77.5 | 318.4 | 1.9E-98 | 30 |
| 3.30.200.20 | Mitogen-activated protein kinase 14
3.30.200.20-FF-2587
|
4
|
SKCM (2)
LUAD (2)
|
96.2 | 130.9 | 2.7E-41 | 1587 |
| 3.30.200.20 | Fibroblast growth factor receptor
3.30.200.20-FF-267
|
2
|
UCEC (2)
|
88.5 | 127.2 | 1.2E-40 | 381 |
| 3.30.200.20 | ALK tyrosine kinase receptor
3.30.200.20-FF-411
|
8
|
UCEC (4)
LUAD (2)
COAD (2)
|
85.5 | 157.5 | 1.2E-50 | 238 |
| 3.30.200.20 | Receptor-type tyrosine-protein kinase FLT3
3.30.200.20-FF-1539
|
10
|
SKCM (8)
CESC (2)
|
80.8 | 215.4 | 9.6E-68 | 107 |
| 3.30.200.20 | Epidermal growth factor receptor
3.30.200.20-FF-2866
|
6
|
BRCA (2)
GBM (2)
UCEC (2)
|
74.2 | 163.2 | 4.4E-52 | 284 |
| 3.30.200.20 | Tyrosine-protein kinase JAK2
3.30.200.20-FF-1690
|
2
|
STAD (2)
|
70.9 | 187.2 | 1.2E-59 | 180 |
| 3.30.200.20 | Beta-adrenergic receptor kinase 1
3.30.200.20-FF-1717
|
6
|
UCEC (2)
ESCA (2)
STAD (2)
|
77.0 | 120.2 | 3.3E-38 | 577 |
| 3.30.200.20 | Interferon-induced, double-stranded RNA-activated protein kinase
3.30.200.20-FF-476
|
2
|
LIHC (2)
|
90.0 | 142.1 | 1.5E-45 | 40 |
| 3.30.200.20 | MAP/microtubule affinity-regulating kinase 3
3.30.200.20-FF-602
|
2
|
UCEC (2)
|
94.0 | 114.3 | 2.3E-36 | 1071 |