| Superfamily | Functional Family | Mutation Events | Mutation Types | DOPS | Incl. Bitscore | Incl. Evalue | Seqs |
|---|---|---|---|---|---|---|---|
| 3.40.30.10 | Thioredoxin-like protein 4A homolog
3.40.30.10-FF-79005
|
4
|
CESC (2)
LGG (2)
|
74.8 | 181.6 | 1.6E-55 | 4163 |
| 3.40.30.10 | Calsequestrin
3.40.30.10-FF-79101
|
6
|
LUSC (2)
UCEC (2)
HNSC (2)
|
73.6 | 176.1 | 1.6E-54 | 141 |
| 3.40.50.2000 | Glycosyltransferase 1 domain-containing protein 1
3.40.50.2000-FF-97302
|
2
|
SKCM (2)
|
97.6 | 160.6 | 1.8E-49 | 144 |
| 2.130.10.10 | Gem-associated protein 5
2.130.10.10-FF-25863
|
8
|
UCEC (4)
SKCM (2)
LIHC (2)
|
89.9 | 286.0 | 3.9E-88 | 101 |
| 2.130.10.10 | F-box/WD repeat-containing protein 7
2.130.10.10-FF-102894
|
344
|
STAD (36)
BRCA (8)
CESC (34)
COAD (42)
UCEC (94)
UVM (2)
UCS (32)
BLCA (32)
HNSC (40)
READ (6)
LUSC (8)
ESCA (6)
GBM (2)
SKCM (2)
|
85.6 | 201.1 | 2.3E-62 | 329 |
| 2.130.10.130 | Integrin alpha L
2.130.10.130-FF-8314
|
12
|
GBM (2)
BLCA (2)
LUAD (2)
STAD (4)
UCEC (2)
|
81.2 | 433.7 | 1.6E-132 | 52 |
| 3.30.420.110 | DNA mismatch repair protein msh3
3.30.420.110-FF-2654
|
4
|
LUAD (2)
UCEC (2)
|
85.9 | 174.8 | 1.5E-53 | 359 |
| 3.30.50.10 | Glucocorticoid nuclear receptor variant 1
3.30.50.10-FF-4110
|
14
|
CESC (2)
COAD (2)
UCEC (4)
SKCM (4)
LUSC (2)
|
91.8 | 124.3 | 1.1E-38 | 651 |
| 3.40.470.10 | G/U mismatch-specific DNA glycosylase
3.40.470.10-FF-4994
|
10
|
SKCM (8)
UCEC (2)
|
83.8 | 165.6 | 2.0E-50 | 35007 |
| 3.40.470.10 | Uracil-DNA glycosylase 1
3.40.470.10-FF-4996
|
2
|
LUAD (2)
|
86.0 | 166.4 | 2.3E-49 | 2248 |
| 3.40.720.10 | Ectonucleotide pyrophosphatase/phosphodiesterase family member 2
3.40.720.10-FF-18987
|
2
|
LUSC (2)
|
72.4 | 245.8 | 1.5E-75 | 121 |
| 3.40.720.10 | Ectonucleotide pyrophosphatase/phosphodiesterase family member 6
3.40.720.10-FF-19063
|
2
|
SKCM (2)
|
85.7 | 319.0 | 1.2E-97 | 106 |
| 3.40.720.10 | Mucin-desulfating sulfatase (N-acetylglucosamine-6-sulfatase)
3.40.720.10-FF-19128
|
2
|
STAD (2)
|
91.1 | 150.8 | 6.1E-46 | 3344 |
| 2.60.120.620 | Prolyl 3-hydroxylase OGFOD1
2.60.120.620-FF-7066
|
6
|
UCEC (4)
STAD (2)
|
85.8 | 264.8 | 2.3E-82 | 107 |
| 3.40.50.10140 | Interleukin-1 receptor type 1
3.40.50.10140-FF-4407
|
2
|
SKCM (2)
|
94.2 | 123.8 | 2.0E-37 | 881 |
| 3.80.10.10 | S-phase kinase-associated protein 2
3.80.10.10-FF-105028
|
20
|
BLCA (2)
LUSC (4)
STAD (2)
UCEC (4)
SKCM (4)
READ (2)
LGG (2)
|
70.7 | 566.5 | 4.9E-173 | 58 |
| 3.80.10.10 | Follicle stimulating hormone receptor
3.80.10.10-FF-105163
|
6
|
STAD (2)
BRCA (2)
LUSC (2)
|
84.0 | 427.1 | 1.6E-130 | 68 |
| 3.80.10.10 | Toll like receptor 4
3.80.10.10-FF-106855
|
12
|
SKCM (4)
STAD (8)
|
88.1 | 474.1 | 2.0E-146 | 74 |
| 2.60.40.1460 | Integrin alpha M, isoform CRA_a
2.60.40.1460-FF-697
|
4
|
LUSC (4)
|
93.3 | 223.8 | 4.6E-69 | 82 |
| 3.20.20.70 | Dihydroorotate dehydrogenase, catalytic subunit
3.20.20.70-FF-120787
|
2
|
UCEC (2)
|
93.4 | 140.9 | 1.1E-41 | 7564 |