| Superfamily | Functional Family | Mutation Events | Mutation Types | DOPS | Incl. Bitscore | Incl. Evalue | Seqs |
|---|---|---|---|---|---|---|---|
| 3.30.70.1230 | Guanylate cyclase soluble subunit beta-1
3.30.70.1230-FF-5698
|
6
|
KIRC (2)
SKCM (2)
UCEC (2)
|
78.7 | 304.7 | 1.9E-93 | 238 |
| 3.30.70.1230 | Adenylate cyclase type 2
3.30.70.1230-FF-5743
|
2
|
LUAD (2)
|
82.2 | 223.0 | 2.4E-67 | 988 |
| 3.40.1380.10 | ATP synthase subunit gamma
3.40.1380.10-FF-2296
|
4
|
LUSC (2)
GBM (2)
|
96.6 | 128.9 | 2.7E-39 | 689 |
| 3.90.1200.10 | Probable choline kinase 1
3.90.1200.10-FF-17534
|
12
|
LUSC (2)
CESC (2)
UCEC (4)
BLCA (2)
DLBC (2)
|
84.3 | 115.7 | 9.6E-35 | 1303 |
| 3.90.1200.10 | Acyl-CoA dehydrogenase family member 10
3.90.1200.10-FF-17576
|
4
|
HNSC (2)
SKCM (2)
|
88.6 | 131.8 | 1.2E-39 | 1378 |
| 3.30.200.20 | Aurora kinase A
3.30.200.20-FF-127
|
4
|
BLCA (2)
UCEC (2)
|
82.2 | 146.7 | 9.5E-47 | 1027 |
| 3.30.200.20 | Fibroblast growth factor receptor
3.30.200.20-FF-267
|
2
|
UCEC (2)
|
88.5 | 127.2 | 1.2E-40 | 381 |
| 3.30.200.20 | ALK tyrosine kinase receptor
3.30.200.20-FF-411
|
8
|
UCEC (4)
LUAD (2)
COAD (2)
|
85.5 | 157.5 | 1.2E-50 | 238 |
| 3.30.200.20 | Interferon-induced, double-stranded RNA-activated protein kinase
3.30.200.20-FF-476
|
2
|
LIHC (2)
|
90.0 | 142.1 | 1.5E-45 | 40 |
| 3.30.200.20 | Serine/threonine-protein kinase 25
3.30.200.20-FF-3028
|
10
|
UCEC (4)
COAD (2)
BLCA (2)
PRAD (2)
|
76.8 | 136.7 | 1.2E-43 | 349 |
| 3.30.200.20 | Calcium/calmodulin-dependent protein kinase type 1G
3.30.200.20-FF-3249
|
4
|
LUSC (2)
SKCM (2)
|
87.3 | 134.7 | 8.6E-44 | 197 |
| 3.30.200.20 | Tyrosine-protein kinase HCK
3.30.200.20-FF-3754
|
6
|
UCEC (2)
SKCM (4)
|
72.3 | 161.3 | 2.8E-51 | 116 |
| 3.30.200.20 | Receptor tyrosine-protein kinase erbB-4
3.30.200.20-FF-3940
|
2
|
SKCM (2)
|
98.2 | 98.9 | 1.2E-31 | 272 |
| 3.30.200.20 | Phosphorylase kinase catalytic subunit PHKG2 homolog protein
3.30.200.20-FF-66370
|
2
|
UCEC (2)
|
87.0 | 144.5 | 4.1E-46 | 155 |
| 3.30.60.20 | Kinase C alpha type
3.30.60.20-FF-92
|
2
|
SKCM (2)
|
78.9 | 137.1 | 5.6E-43 | 305 |
| 3.60.21.10 | Metallophosphoesterase domain-containing protein 1
3.60.21.10-FF-29492
|
2
|
UCEC (2)
|
92.1 | 262.1 | 3.5E-80 | 1619 |
| 3.60.21.10 | Bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase protein
3.60.21.10-FF-29502
|
2
|
LIHC (2)
|
96.5 | 167.3 | 6.6E-50 | 3123 |
| 1.10.580.10 | Probable citrate synthase, mitochondrial
1.10.580.10-FF-132
|
4
|
LIHC (2)
COAD (2)
|
90.5 | 123.1 | 6.5E-37 | 1581 |
| 2.170.210.10 | Non-homologous end-joining factor 1
2.170.210.10-FF-199
|
10
|
UCEC (8)
CESC (2)
|
90.3 | 125.3 | 5.6E-39 | 74 |
| 2.20.160.10 | Titin-cap
2.20.160.10-FF-13
|
4
|
BRCA (2)
PRAD (2)
|
79.1 | 129.0 | 1.3E-40 | 50 |