| Superfamily | Functional Family | Mutation Events | Mutation Types | DOPS | Incl. Bitscore | Incl. Evalue | Seqs |
|---|---|---|---|---|---|---|---|
| 3.90.520.10 | Mothers against decapentaplegic homolog
3.90.520.10-FF-189
|
18
|
LUAD (4)
PAAD (2)
CESC (2)
BLCA (2)
UCEC (4)
KIRP (2)
COAD (2)
|
85.1 | 191.7 | 4.9E-59 | 555 |
| 1.10.275.10 | Fumarate hydratase class II
1.10.275.10-FF-7494
|
2
|
HNSC (2)
|
90.5 | 112.8 | 6.6E-33 | 2231 |
| 1.10.3380.10 | Small nuclear ribonucleoprotein helicase
1.10.3380.10-FF-1043
|
4
|
UCEC (4)
|
96.5 | 163.9 | 7.5E-50 | 1143 |
| 3.10.100.10 | C-type lectin domain family 4 member E
3.10.100.10-FF-12415
|
2
|
SKCM (2)
|
85.3 | 151.4 | 1.6E-46 | 202 |
| 3.10.100.10 | Natural killer cell receptor-P1
3.10.100.10-FF-12450
|
4
|
SKCM (4)
|
98.6 | 109.9 | 6.1E-34 | 169 |
| 3.40.50.150 | 5-methylcytosine rRNA methyltransferase NSUN4
3.40.50.150-FF-133326
|
6
|
LUSC (4)
COAD (2)
|
72.2 | 314.3 | 1.4E-96 | 48 |
| 3.60.20.30 | Putative N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase CG1827
3.60.20.30-FF-891
|
12
|
COAD (2)
LUSC (4)
STAD (2)
GBM (2)
UCEC (2)
|
92.5 | 182.2 | 4.8E-56 | 304 |
| 1.20.80.10 | Acyl-CoA-binding domain-containing protein 7
1.20.80.10-FF-2727
|
16
|
BLCA (2)
COAD (4)
STAD (2)
SKCM (4)
PRAD (2)
UCEC (2)
|
93.9 | 114.9 | 1.9E-35 | 626 |
| 2.30.42.10 | Harmonin isoform b4
2.30.42.10-FF-865
|
4
|
UCEC (2)
HNSC (2)
|
73.5 | 196.0 | 7.1E-61 | 90 |
| 2.30.42.10 | Multiple PDZ domain protein
2.30.42.10-FF-23445
|
6
|
LUSC (2)
READ (2)
BRCA (2)
|
71.7 | 199.7 | 7.2E-62 | 166 |
| 2.30.42.10 | FERM and PDZ domain-containing protein 1
2.30.42.10-FF-24070
|
10
|
BLCA (2)
LIHC (2)
UCEC (2)
LUAD (2)
SKCM (2)
|
87.8 | 98.3 | 8.2E-31 | 59 |
| 2.60.120.560 | Galactocerebrosidase
2.60.120.560-FF-3212
|
12
|
UCEC (4)
THYM (2)
LIHC (2)
UCS (2)
PAAD (2)
|
95.2 | 107.8 | 4.6E-33 | 146 |
| 2.60.40.60 | Protocadherin alpha 2
2.60.40.60-FF-18149
|
36
|
LUAD (8)
LUSC (4)
STAD (6)
LGG (2)
BRCA (2)
PRAD (4)
COAD (4)
HNSC (4)
UCEC (2)
|
86.5 | 162.5 | 4.8E-50 | 218 |
| 3.10.130.10 | Ribonuclease pancreatic beta-type
3.10.130.10-FF-658
|
4
|
LIHC (2)
SKCM (2)
|
94.0 | 129.3 | 1.2E-39 | 294 |
| 3.30.499.10 | Probable aconitate hydratase, mitochondrial
3.30.499.10-FF-6840
|
6
|
UCEC (4)
COAD (2)
|
85.9 | 302.0 | 7.9E-92 | 1645 |
| 1.25.40.150 | V-type proton ATPase subunit H
1.25.40.150-FF-600
|
2
|
STAD (2)
|
94.7 | 116.4 | 1.1E-35 | 700 |
| 3.30.420.40 | Putative xylulose kinase protein
3.30.420.40-FF-76355
|
2
|
BLCA (2)
|
89.3 | 354.6 | 1.1E-107 | 805 |
| 3.30.420.40 | Actin-related protein, ARP1 class
3.30.420.40-FF-77722
|
10
|
STAD (4)
UCS (2)
BRCA (2)
KIRP (2)
|
92.1 | 188.3 | 1.9E-57 | 3090 |
| 3.30.460.10 | 2'-5'-oligoadenylate synthase-like protein 2
3.30.460.10-FF-18008
|
2
|
LUSC (2)
|
92.8 | 214.1 | 1.8E-66 | 36 |
| 2.20.25.20 | Casein kinase II subunit beta
2.20.25.20-FF-218
|
6
|
BLCA (2)
GBM (2)
COAD (2)
|
82.1 | 165.9 | 8.9E-52 | 1436 |