| Superfamily | Functional Family | Mutation Events | Mutation Types | DOPS | Incl. Bitscore | Incl. Evalue | Seqs |
|---|---|---|---|---|---|---|---|
| 2.60.120.260 | Ephrin type-A receptor 3
2.60.120.260-FF-35252
|
2
|
SKCM (2)
|
91.9 | 164.3 | 1.3E-49 | 989 |
| 2.60.120.260 | Coagulation factor V
2.60.120.260-FF-35405
|
2
|
LUSC (2)
|
85.5 | 253.4 | 4.9E-78 | 114 |
| 2.70.160.11 | Protein arginine N-methyltransferase 5
2.70.160.11-FF-1297
|
6
|
COAD (2)
STAD (2)
UCEC (2)
|
74.6 | 150.4 | 5.0E-46 | 453 |
| 2.70.160.11 | Protein arginine N-methyltransferase 1
2.70.160.11-FF-1304
|
2
|
UCEC (2)
|
82.6 | 120.3 | 6.4E-36 | 1242 |
| 2.60.120.260 | Anaphase-promoting complex subunit 10
2.60.120.260-FF-35426
|
2
|
LGG (2)
|
92.8 | 196.4 | 2.0E-60 | 1582 |
| 3.90.1460.10 | General transcription factor II-I
3.90.1460.10-FF-79
|
8
|
LUAD (2)
LIHC (2)
SKCM (2)
KIRP (2)
|
96.4 | 103.2 | 1.1E-31 | 291 |
| 3.40.718.10 | Isocitrate dehydrogenase [NAD] subunit, mitochondrial
3.40.718.10-FF-5154
|
2
|
UCEC (2)
|
81.9 | 112.6 | 2.5E-34 | 493 |
| 3.40.630.30 | Alpha-tubulin N-acetyltransferase 1
3.40.630.30-FF-70368
|
2
|
UCEC (2)
|
88.5 | 265.9 | 9.2E-83 | 116 |
| 3.40.630.30 | N(Alpha)-acetyltransferase 50, NatE catalytic subunit
3.40.630.30-FF-70410
|
6
|
PRAD (2)
LUSC (2)
STAD (2)
|
97.8 | 179.4 | 3.2E-55 | 950 |
| 3.40.630.30 | N-alpha-acetyltransferase 60
3.40.630.30-FF-70517
|
18
|
GBM (2)
LUSC (2)
KIRC (4)
SKCM (2)
CESC (2)
PAAD (4)
HNSC (2)
|
87.6 | 196.0 | 2.8E-60 | 248 |
| 2.10.220.10 | Epidermal growth factor receptor
2.10.220.10-FF-11249
|
74
|
GBM (54)
LGG (16)
BRCA (2)
HNSC (2)
|
82.1 | 111.5 | 4.1E-36 | 128 |
| 3.90.226.10 | Acetyl-CoA carboxylase 2
3.90.226.10-FF-34021
|
6
|
SKCM (2)
COAD (2)
BRCA (2)
|
89.6 | 216.1 | 2.2E-66 | 797 |
| 3.90.226.10 | Enoyl-CoA hydratase/isomerase family, putative
3.90.226.10-FF-34054
|
14
|
SKCM (2)
UCEC (6)
STAD (2)
COAD (2)
LUSC (2)
|
85.3 | 220.3 | 4.0E-67 | 1259 |
| 1.20.120.550 | Microsomal glutathione S-transferase 2
1.20.120.550-FF-1700
|
10
|
LUSC (2)
SKCM (2)
COAD (2)
UCEC (2)
PAAD (2)
|
88.5 | 107.5 | 9.2E-33 | 431 |
| 3.90.226.10 | Chromodomain Y-like protein 2
3.90.226.10-FF-33545
|
4
|
LIHC (2)
UCEC (2)
|
80.0 | 341.9 | 1.2E-104 | 267 |
| 2.10.220.10 | Ovarian R-spondin member 2
2.10.220.10-FF-11341
|
18
|
PRAD (2)
UCEC (4)
BLCA (2)
STAD (4)
LUAD (4)
SKCM (2)
|
90.5 | 137.4 | 1.5E-42 | 213 |
| 2.10.220.10 | Receptor tyrosine-protein kinase erbB-2
2.10.220.10-FF-5834
|
90
|
STAD (14)
BLCA (46)
CESC (14)
BRCA (2)
UCEC (2)
ESCA (4)
LUAD (2)
COAD (2)
HNSC (2)
OV (2)
|
72.6 | 174.5 | 3.2E-56 | 73 |
| 2.30.30.100 | Small nuclear ribonucleoprotein-associated protein
2.30.30.100-FF-5260
|
14
|
STAD (8)
COAD (2)
ESCA (2)
SKCM (2)
|
86.7 | 158.1 | 3.6E-49 | 689 |
| 3.10.129.10 | Cytosolic acyl coenzyme A thioester hydrolase
3.10.129.10-FF-29377
|
10
|
UCEC (6)
CESC (2)
SKCM (2)
|
77.7 | 251.9 | 9.6E-78 | 100 |
| 2.60.40.1480 | Probable coatomer subunit gamma
2.60.40.1480-FF-229
|
2
|
LUSC (2)
|
88.5 | 125.8 | 5.2E-38 | 1257 |