| Superfamily | Functional Family | Mutation Events | Mutation Types | DOPS | Incl. Bitscore | Incl. Evalue | Seqs |
|---|---|---|---|---|---|---|---|
| 2.30.30.100 | Small nuclear ribonucleoprotein-associated protein
2.30.30.100-FF-5260
|
14
|
STAD (8)
COAD (2)
ESCA (2)
SKCM (2)
|
86.7 | 158.1 | 3.6E-49 | 689 |
| 3.10.129.10 | Cytosolic acyl coenzyme A thioester hydrolase
3.10.129.10-FF-29377
|
10
|
UCEC (6)
CESC (2)
SKCM (2)
|
77.7 | 251.9 | 9.6E-78 | 100 |
| 3.10.129.10 | Acyl-coenzyme A thioesterase 13
3.10.129.10-FF-29575
|
4
|
UCEC (4)
|
71.3 | 250.1 | 7.8E-78 | 32 |
| 3.30.70.940 | Transcription elongation factor SPT5
3.30.70.940-FF-1945
|
4
|
BRCA (2)
UCEC (2)
|
89.8 | 162.5 | 1.4E-50 | 256 |
| 3.40.250.10 | Adenylyltransferase and sulfurtransferase MOCS3
3.40.250.10-FF-16081
|
2
|
STAD (2)
|
79.4 | 181.1 | 3.1E-56 | 85 |
| 3.40.1770.10 | Probable urocanate hydratase
3.40.1770.10-FF-932
|
6
|
CESC (2)
SKCM (4)
|
95.3 | 137.5 | 7.2E-42 | 1582 |
| 3.40.50.10590 | Probable aminopeptidase NPEPL1
3.40.50.10590-FF-47
|
4
|
CESC (2)
BLCA (2)
|
91.6 | 181.1 | 3.4E-56 | 52 |
| 3.40.710.10 | Beta-lactamase (Penicillin-binding protein) (Penicillinase)
3.40.710.10-FF-22194
|
8
|
COAD (2)
UCEC (2)
READ (4)
|
94.6 | 118.1 | 6.3E-35 | 2353 |
| 3.40.50.970 | Pyruvate dehydrogenase beta subunit
3.40.50.970-FF-36356
|
8
|
GBM (4)
UCEC (4)
|
90.5 | 206.1 | 7.4E-62 | 4651 |
| 3.40.50.970 | Probable 2-hydroxyacyl-CoA lyase 1
3.40.50.970-FF-36507
|
6
|
UCEC (2)
CESC (2)
LIHC (2)
|
92.9 | 172.5 | 2.6E-52 | 5790 |
| 3.90.70.10 | Cathepsin B-like cysteine protease
3.90.70.10-FF-17146
|
12
|
SKCM (4)
UCEC (4)
STAD (2)
CESC (2)
|
83.7 | 141.2 | 4.3E-42 | 1011 |
| 1.10.275.10 | Fumarate hydratase class II
1.10.275.10-FF-7494
|
2
|
HNSC (2)
|
90.5 | 112.8 | 6.6E-33 | 2231 |
| 3.90.70.10 | Ubl carboxyl-terminal hydrolase 18
3.90.70.10-FF-16776
|
10
|
BLCA (2)
UCEC (2)
COAD (2)
SARC (2)
SKCM (2)
|
74.1 | 590.1 | 1.6E-180 | 41 |
| 3.90.70.10 | Aminopeptidase C (Bleomycin hydrolase)
3.90.70.10-FF-16963
|
2
|
UCEC (2)
|
87.3 | 367.0 | 6.0E-111 | 3058 |
| 3.90.520.10 | Mothers against decapentaplegic homolog
3.90.520.10-FF-185
|
2
|
UCEC (2)
|
88.7 | 162.5 | 1.7E-49 | 2832 |
| 3.90.520.10 | Mothers against decapentaplegic homolog
3.90.520.10-FF-189
|
18
|
LUAD (4)
PAAD (2)
CESC (2)
BLCA (2)
UCEC (4)
KIRP (2)
COAD (2)
|
85.1 | 191.7 | 4.9E-59 | 555 |
| 3.10.100.10 | Asialoglycoprotein receptor 1
3.10.100.10-FF-12228
|
10
|
SKCM (6)
UCEC (2)
STAD (2)
|
87.8 | 172.9 | 2.1E-53 | 123 |
| 1.10.1300.10 | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A
1.10.1300.10-FF-1247
|
14
|
UCEC (8)
LUSC (2)
ACC (2)
COAD (2)
|
84.5 | 494.3 | 9.9E-151 | 178 |
| 1.20.1200.10 | Cob(I)yrinic acid a,c-diamide adenosyltransferase
1.20.1200.10-FF-1240
|
4
|
UCEC (2)
HNSC (2)
|
90.7 | 176.8 | 2.5E-54 | 314 |
| 2.60.210.10 | Speckle-type POZ protein B
2.60.210.10-FF-909
|
106
|
PRAD (74)
UCEC (18)
LUSC (4)
DLBC (2)
LGG (2)
ESCA (2)
BLCA (2)
ACC (2)
|
97.9 | 145.6 | 6.2E-45 | 1444 |