| Superfamily | Functional Family | Mutation Events | Mutation Types | DOPS | Incl. Bitscore | Incl. Evalue | Seqs |
|---|---|---|---|---|---|---|---|
| 3.40.50.10190 | DNA topoisomerase 2-binding protein 1
3.40.50.10190-FF-8728
|
2
|
BRCA (2)
|
71.1 | 183.8 | 2.1E-57 | 80 |
| 3.40.50.10190 | DNA topoisomerase 2-binding protein 1
3.40.50.10190-FF-8827
|
4
|
BLCA (2)
CESC (2)
|
76.2 | 162.7 | 7.9E-51 | 80 |
| 2.40.50.90 | Staphylococcal nuclease domain-containing protein 1
2.40.50.90-FF-3147
|
8
|
SARC (2)
STAD (4)
COAD (2)
|
89.0 | 134.1 | 4.4E-41 | 381 |
| 2.60.40.340 | Transcription factor RelB homolog
2.60.40.340-FF-248
|
6
|
UCEC (4)
CESC (2)
|
79.6 | 155.6 | 2.3E-47 | 553 |
| 2.60.40.340 | Nuclear factor of activated T-cells 5
2.60.40.340-FF-249
|
18
|
LUSC (2)
STAD (2)
BLCA (2)
UCEC (4)
GBM (2)
BRCA (2)
LUAD (2)
SKCM (2)
|
92.2 | 194.7 | 3.0E-59 | 736 |
| 3.40.50.2020 | Phosphoribosyltransferase domain-containing protein 1
3.40.50.2020-FF-18395
|
2
|
UCEC (2)
|
86.9 | 253.7 | 1.8E-77 | 733 |
| 1.20.900.10 | Son of sevenless 1
1.20.900.10-FF-3285
|
24
|
LUSC (4)
UCEC (12)
LUAD (8)
|
88.0 | 280.2 | 1.3E-85 | 218 |
| 3.40.50.2020 | Adenine phosphoribosyltransferase, isoform C
3.40.50.2020-FF-18599
|
12
|
SKCM (2)
STAD (2)
BLCA (2)
CESC (2)
LUSC (2)
UCEC (2)
|
91.3 | 171.0 | 2.0E-52 | 627 |
| 3.90.180.10 | Quinone oxidoreductase Qor
3.90.180.10-FF-34016
|
2
|
SKCM (2)
|
93.0 | 128.2 | 1.1E-39 | 622 |
| 3.90.180.10 | Quinone oxidoreductase isoform a
3.90.180.10-FF-34032
|
6
|
SKCM (4)
STAD (2)
|
89.9 | 150.6 | 1.6E-46 | 134 |
| 1.10.287.80 | Lysine-specific histone demethylase 1A
1.10.287.80-FF-3084
|
6
|
UCEC (4)
BLCA (2)
|
97.8 | 102.2 | 1.8E-31 | 221 |
| 1.20.900.10 | Rho guanine nucleotide exchange factor 7
1.20.900.10-FF-3298
|
6
|
UCEC (4)
COAD (2)
|
91.3 | 296.2 | 1.4E-90 | 288 |
| 1.20.900.10 | FERM, RhoGEF and pleckstrin domain-containing protein 1
1.20.900.10-FF-3306
|
2
|
LUSC (2)
|
92.1 | 319.8 | 8.1E-98 | 237 |
| 1.25.10.20 | Microsomal triglyceride transfer protein
1.25.10.20-FF-1443
|
2
|
SKCM (2)
|
90.5 | 121.7 | 1.4E-36 | 794 |
| 1.25.40.70 | Phosphatidylinositol 3-kinase gamma isoform
1.25.40.70-FF-2223
|
970
|
STAD (44)
BLCA (106)
COAD (84)
UCEC (116)
ESCA (12)
BRCA (212)
CESC (128)
HNSC (98)
KIRP (8)
LUSC (66)
TGCT (4)
UCS (14)
LUAD (24)
LGG (12)
SKCM (10)
READ (4)
GBM (14)
LIHC (4)
PRAD (6)
KIRC (2)
CHOL (2)
|
92.3 | 106.5 | 6.2E-32 | 1101 |
| 2.10.50.10 | TNF receptor superfamily, member 1A
2.10.50.10-FF-7632
|
4
|
UCEC (4)
|
82.2 | 101.1 | 6.8E-32 | 45 |
| 3.10.20.90 | Transcription elongation factor B polypeptide 2
3.10.20.90-FF-1161
|
2
|
UCEC (2)
|
84.9 | 168.8 | 5.3E-53 | 122 |
| 3.10.20.90 | Homocysteine-induced endoplasmic reticulum protein, isoform A
3.10.20.90-FF-16288
|
2
|
LGG (2)
|
80.3 | 138.5 | 1.7E-43 | 49 |
| 3.10.20.90 | Phosphoinositide phospholipase C
3.10.20.90-FF-15929
|
10
|
SKCM (2)
DLBC (2)
LGG (2)
STAD (2)
COAD (2)
|
76.8 | 152.2 | 3.1E-47 | 131 |
| 3.10.20.90 | Plexin A4 isoform 1
3.10.20.90-FF-15968
|
2
|
UCEC (2)
|
72.1 | 169.4 | 2.7E-53 | 419 |