Functional Families
Browse Information on Functional Families (FunFams) in CATH
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Showing 401 to 420 of 884 entries
Superfamily Functional Family Mutation Events Mutation Types DOPS Incl. Bitscore Incl. Evalue Seqs
3.40.50.10190 PAX-interacting protein 1
3.40.50.10190-FF-8685
2
LUSC (2)
83.4 164.8 3.1E-51 118
3.40.50.10190 Protein ECT2
3.40.50.10190-FF-6404
6
UCEC (2)
LUSC (2)
READ (2)
82.8 121.1 9.6E-38 94
3.40.50.10190 DNA topoisomerase 2-binding protein 1
3.40.50.10190-FF-8728
2
BRCA (2)
71.1 183.8 2.1E-57 80
3.40.50.10190 DNA topoisomerase 2-binding protein 1
3.40.50.10190-FF-8827
4
BLCA (2)
CESC (2)
76.2 162.7 7.9E-51 80
3.90.180.10 Quinone oxidoreductase Qor
3.90.180.10-FF-34016
2
SKCM (2)
93.0 128.2 1.1E-39 622
3.40.910.10 Probable deoxyhypusine synthase 1
3.40.910.10-FF-602
10
UCEC (8)
STAD (2)
88.6 243.2 2.1E-73 1553
3.40.50.2020 Phosphoribosyltransferase domain-containing protein 1
3.40.50.2020-FF-18395
2
UCEC (2)
86.9 253.7 1.8E-77 733
3.40.50.2020 Adenine phosphoribosyltransferase, isoform C
3.40.50.2020-FF-18599
12
SKCM (2)
STAD (2)
BLCA (2)
CESC (2)
LUSC (2)
UCEC (2)
91.3 171.0 2.0E-52 627
3.90.180.10 Quinone oxidoreductase isoform a
3.90.180.10-FF-34032
6
SKCM (4)
STAD (2)
89.9 150.6 1.6E-46 134
1.10.287.80 Lysine-specific histone demethylase 1A
1.10.287.80-FF-3084
6
UCEC (4)
BLCA (2)
97.8 102.2 1.8E-31 221
2.10.50.10 TNF receptor superfamily, member 1A
2.10.50.10-FF-7632
4
UCEC (4)
82.2 101.1 6.8E-32 45
1.20.900.10 Son of sevenless 1
1.20.900.10-FF-3285
24
LUSC (4)
UCEC (12)
LUAD (8)
88.0 280.2 1.3E-85 218
1.20.900.10 Rho guanine nucleotide exchange factor 7
1.20.900.10-FF-3298
6
UCEC (4)
COAD (2)
91.3 296.2 1.4E-90 288
1.20.900.10 FERM, RhoGEF and pleckstrin domain-containing protein 1
1.20.900.10-FF-3306
2
LUSC (2)
92.1 319.8 8.1E-98 237
3.10.20.90 Transcription elongation factor B polypeptide 2
3.10.20.90-FF-1161
2
UCEC (2)
84.9 168.8 5.3E-53 122
1.25.10.20 Microsomal triglyceride transfer protein
1.25.10.20-FF-1443
2
SKCM (2)
90.5 121.7 1.4E-36 794
1.25.40.70 Phosphatidylinositol 3-kinase gamma isoform
1.25.40.70-FF-2223
970
STAD (44)
BLCA (106)
COAD (84)
UCEC (116)
ESCA (12)
BRCA (212)
CESC (128)
HNSC (98)
KIRP (8)
LUSC (66)
TGCT (4)
UCS (14)
LUAD (24)
LGG (12)
SKCM (10)
READ (4)
GBM (14)
LIHC (4)
PRAD (6)
KIRC (2)
CHOL (2)
92.3 106.5 6.2E-32 1101
3.10.20.90 Phosphoinositide phospholipase C
3.10.20.90-FF-15929
10
SKCM (2)
DLBC (2)
LGG (2)
STAD (2)
COAD (2)
76.8 152.2 3.1E-47 131
3.10.20.90 Plexin A4 isoform 1
3.10.20.90-FF-15968
2
UCEC (2)
72.1 169.4 2.7E-53 419
3.30.1370.10 RNA-binding E3 ubiquitin-protein ligase MEX3C
3.30.1370.10-FF-8205
8
UCEC (6)
COAD (2)
82.6 118.9 8.7E-37 438