| Superfamily | Functional Family | Mutation Events | Mutation Types | DOPS | Incl. Bitscore | Incl. Evalue | Seqs |
|---|---|---|---|---|---|---|---|
| 3.40.47.10 | 3-ketoacyl-CoA thiolase A, peroxisomal
3.40.47.10-FF-52261
|
6
|
UCEC (2)
ESCA (2)
LIHC (2)
|
84.7 | 189.7 | 1.7E-57 | 1571 |
| 3.40.47.10 | 3-ketoacyl-CoA thiolase, mitochondrial
3.40.47.10-FF-52357
|
4
|
LUAD (2)
BRCA (2)
|
88.9 | 336.4 | 3.1E-103 | 168 |
| 3.40.47.10 | Acetyl-CoA acetyltransferase, cytosolic variant
3.40.47.10-FF-52421
|
2
|
SKCM (2)
|
94.5 | 186.6 | 1.5E-57 | 298 |
| 3.90.470.20 | L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase
3.90.470.20-FF-5532
|
4
|
UCEC (2)
SKCM (2)
|
84.0 | 173.1 | 9.4E-54 | 96 |
| 3.90.470.20 | L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase
3.90.470.20-FF-5616
|
8
|
LUSC (2)
UCEC (4)
LUAD (2)
|
80.7 | 208.7 | 9.7E-65 | 97 |
| 2.30.30.190 | Ubiquitin carboxyl-terminal hydrolase CYLD
2.30.30.190-FF-145
|
4
|
GBM (2)
COAD (2)
|
71.1 | 149.0 | 1.3E-46 | 99 |
| 2.30.30.190 | Tubulin folding cofactor B
2.30.30.190-FF-1175
|
2
|
SKCM (2)
|
85.3 | 128.4 | 3.8E-40 | 156 |
| 2.40.30.110 | Dimethylglycine dehydrogenase, mitochondrial
2.40.30.110-FF-2948
|
4
|
COAD (2)
SKCM (2)
|
86.5 | 112.0 | 2.2E-35 | 89 |
| 2.60.40.790 | Calcyclin-binding protein
2.60.40.790-FF-5141
|
6
|
COAD (2)
UCEC (2)
LUSC (2)
|
84.5 | 179.4 | 6.5E-56 | 109 |
| 2.60.40.790 | Prostaglandin E synthase 3
2.60.40.790-FF-7583
|
2
|
UCEC (2)
|
79.6 | 225.3 | 7.2E-70 | 633 |
| 2.80.10.50 | Polypeptide N-acetylgalactosaminyltransferase 10
2.80.10.50-FF-13020
|
2
|
SKCM (2)
|
72.8 | 300.2 | 1.5E-92 | 133 |
| 2.80.10.50 | Fibroblast growth factor 9
2.80.10.50-FF-13030
|
2
|
SKCM (2)
|
90.3 | 201.4 | 5.5E-62 | 1667 |
| 2.80.10.50 | Fibroblast growth factor 7
2.80.10.50-FF-13074
|
6
|
SKCM (4)
GBM (2)
|
84.6 | 182.8 | 1.2E-56 | 784 |
| 3.50.50.60 | Dihydrolipoyl dehydrogenase, mitochondrial
3.50.50.60-FF-78468
|
8
|
LUAD (2)
STAD (2)
PRAD (2)
UCEC (2)
|
75.6 | 185.2 | 4.5E-59 | 214 |
| 1.10.800.10 | Aromatic amino acid hydroxylase 1
1.10.800.10-FF-550
|
6
|
SKCM (6)
|
83.6 | 332.8 | 1.0E-100 | 1032 |
| 3.20.20.140 | AMP deaminase, isoform K
3.20.20.140-FF-39821
|
8
|
UCEC (6)
COAD (2)
|
83.8 | 185.3 | 7.1E-56 | 1232 |
| 3.20.20.140 | Putative D-hydantoinase (Dihydropyrimidinase)
3.20.20.140-FF-40287
|
2
|
SKCM (2)
|
92.0 | 256.0 | 5.7E-77 | 1750 |
| 3.30.505.10 | Cytokine-dependent hematopoietic cell linker
3.30.505.10-FF-4294
|
6
|
LUSC (2)
CESC (2)
UCEC (2)
|
93.2 | 160.4 | 1.1E-49 | 164 |
| 3.40.50.10470 | Putative methylthioribose-1-phosphate isomerase protein
3.40.50.10470-FF-1910
|
2
|
HNSC (2)
|
90.5 | 192.1 | 8.5E-58 | 1443 |
| 3.40.50.261 | ATP-citrate synthase subunit 1
3.40.50.261-FF-4818
|
2
|
PAAD (2)
|
85.9 | 229.9 | 7.3E-70 | 1203 |