| Superfamily | Functional Family | Mutation Events | Mutation Types | DOPS | Incl. Bitscore | Incl. Evalue | Seqs |
|---|---|---|---|---|---|---|---|
| 1.10.510.10 | Insulin receptor
1.10.510.10-FF-79449
|
2
|
UCEC (2)
|
85.5 | 179.4 | 1.9E-56 | 77 |
| 3.40.50.10190 | Protein ECT2
3.40.50.10190-FF-6404
|
6
|
UCEC (2)
LUSC (2)
READ (2)
|
82.8 | 121.1 | 9.6E-38 | 94 |
| 3.40.50.10190 | PAX-interacting protein 1
3.40.50.10190-FF-8685
|
2
|
LUSC (2)
|
83.4 | 164.8 | 3.1E-51 | 118 |
| 3.40.50.10190 | DNA topoisomerase 2-binding protein 1
3.40.50.10190-FF-8728
|
2
|
BRCA (2)
|
71.1 | 183.8 | 2.1E-57 | 80 |
| 3.40.50.10190 | DNA topoisomerase 2-binding protein 1
3.40.50.10190-FF-8827
|
4
|
BLCA (2)
CESC (2)
|
76.2 | 162.7 | 7.9E-51 | 80 |
| 3.40.50.2020 | Phosphoribosyltransferase domain-containing protein 1
3.40.50.2020-FF-18395
|
2
|
UCEC (2)
|
86.9 | 253.7 | 1.8E-77 | 733 |
| 1.10.287.80 | Lysine-specific histone demethylase 1A
1.10.287.80-FF-3084
|
6
|
UCEC (4)
BLCA (2)
|
97.8 | 102.2 | 1.8E-31 | 221 |
| 3.40.50.2020 | Adenine phosphoribosyltransferase, isoform C
3.40.50.2020-FF-18599
|
12
|
SKCM (2)
STAD (2)
BLCA (2)
CESC (2)
LUSC (2)
UCEC (2)
|
91.3 | 171.0 | 2.0E-52 | 627 |
| 3.90.180.10 | Quinone oxidoreductase Qor
3.90.180.10-FF-34016
|
2
|
SKCM (2)
|
93.0 | 128.2 | 1.1E-39 | 622 |
| 3.90.180.10 | Quinone oxidoreductase isoform a
3.90.180.10-FF-34032
|
6
|
SKCM (4)
STAD (2)
|
89.9 | 150.6 | 1.6E-46 | 134 |
| 3.10.20.90 | Transcription elongation factor B polypeptide 2
3.10.20.90-FF-1161
|
2
|
UCEC (2)
|
84.9 | 168.8 | 5.3E-53 | 122 |
| 2.10.50.10 | TNF receptor superfamily, member 1A
2.10.50.10-FF-7632
|
4
|
UCEC (4)
|
82.2 | 101.1 | 6.8E-32 | 45 |
| 1.20.900.10 | Son of sevenless 1
1.20.900.10-FF-3285
|
24
|
LUSC (4)
UCEC (12)
LUAD (8)
|
88.0 | 280.2 | 1.3E-85 | 218 |
| 1.20.900.10 | Rho guanine nucleotide exchange factor 7
1.20.900.10-FF-3298
|
6
|
UCEC (4)
COAD (2)
|
91.3 | 296.2 | 1.4E-90 | 288 |
| 1.20.900.10 | FERM, RhoGEF and pleckstrin domain-containing protein 1
1.20.900.10-FF-3306
|
2
|
LUSC (2)
|
92.1 | 319.8 | 8.1E-98 | 237 |
| 1.25.10.20 | Microsomal triglyceride transfer protein
1.25.10.20-FF-1443
|
2
|
SKCM (2)
|
90.5 | 121.7 | 1.4E-36 | 794 |
| 1.25.40.70 | Phosphatidylinositol 3-kinase gamma isoform
1.25.40.70-FF-2223
|
970
|
STAD (44)
BLCA (106)
COAD (84)
UCEC (116)
ESCA (12)
BRCA (212)
CESC (128)
HNSC (98)
KIRP (8)
LUSC (66)
TGCT (4)
UCS (14)
LUAD (24)
LGG (12)
SKCM (10)
READ (4)
GBM (14)
LIHC (4)
PRAD (6)
KIRC (2)
CHOL (2)
|
92.3 | 106.5 | 6.2E-32 | 1101 |
| 3.30.1370.10 | RNA-binding E3 ubiquitin-protein ligase MEX3C
3.30.1370.10-FF-8205
|
8
|
UCEC (6)
COAD (2)
|
82.6 | 118.9 | 8.7E-37 | 438 |
| 3.10.20.90 | Phosphoinositide phospholipase C
3.10.20.90-FF-15929
|
10
|
SKCM (2)
DLBC (2)
LGG (2)
STAD (2)
COAD (2)
|
76.8 | 152.2 | 3.1E-47 | 131 |
| 3.10.20.90 | Plexin A4 isoform 1
3.10.20.90-FF-15968
|
2
|
UCEC (2)
|
72.1 | 169.4 | 2.7E-53 | 419 |