| Superfamily | Functional Family | Mutation Events | Mutation Types | DOPS | Incl. Bitscore | Incl. Evalue | Seqs |
|---|---|---|---|---|---|---|---|
| 2.60.40.340 | Nuclear factor of activated T-cells 5
2.60.40.340-FF-249
|
18
|
LUSC (2)
STAD (2)
BLCA (2)
UCEC (4)
GBM (2)
BRCA (2)
LUAD (2)
SKCM (2)
|
92.2 | 194.7 | 3.0E-59 | 736 |
| 3.40.50.10190 | DNA topoisomerase 2-binding protein 1
3.40.50.10190-FF-8728
|
2
|
BRCA (2)
|
71.1 | 183.8 | 2.1E-57 | 80 |
| 3.40.50.10190 | Protein ECT2
3.40.50.10190-FF-6404
|
6
|
UCEC (2)
LUSC (2)
READ (2)
|
82.8 | 121.1 | 9.6E-38 | 94 |
| 3.40.50.10190 | DNA topoisomerase 2-binding protein 1
3.40.50.10190-FF-8827
|
4
|
BLCA (2)
CESC (2)
|
76.2 | 162.7 | 7.9E-51 | 80 |
| 3.90.180.10 | Quinone oxidoreductase Qor
3.90.180.10-FF-34016
|
2
|
SKCM (2)
|
93.0 | 128.2 | 1.1E-39 | 622 |
| 3.40.50.2020 | Phosphoribosyltransferase domain-containing protein 1
3.40.50.2020-FF-18395
|
2
|
UCEC (2)
|
86.9 | 253.7 | 1.8E-77 | 733 |
| 3.40.910.10 | Probable deoxyhypusine synthase 1
3.40.910.10-FF-602
|
10
|
UCEC (8)
STAD (2)
|
88.6 | 243.2 | 2.1E-73 | 1553 |
| 3.90.180.10 | Quinone oxidoreductase isoform a
3.90.180.10-FF-34032
|
6
|
SKCM (4)
STAD (2)
|
89.9 | 150.6 | 1.6E-46 | 134 |
| 3.40.50.2020 | Adenine phosphoribosyltransferase, isoform C
3.40.50.2020-FF-18599
|
12
|
SKCM (2)
STAD (2)
BLCA (2)
CESC (2)
LUSC (2)
UCEC (2)
|
91.3 | 171.0 | 2.0E-52 | 627 |
| 1.20.900.10 | Son of sevenless 1
1.20.900.10-FF-3285
|
24
|
LUSC (4)
UCEC (12)
LUAD (8)
|
88.0 | 280.2 | 1.3E-85 | 218 |
| 1.10.287.80 | Lysine-specific histone demethylase 1A
1.10.287.80-FF-3084
|
6
|
UCEC (4)
BLCA (2)
|
97.8 | 102.2 | 1.8E-31 | 221 |
| 1.20.900.10 | Rho guanine nucleotide exchange factor 7
1.20.900.10-FF-3298
|
6
|
UCEC (4)
COAD (2)
|
91.3 | 296.2 | 1.4E-90 | 288 |
| 1.20.900.10 | FERM, RhoGEF and pleckstrin domain-containing protein 1
1.20.900.10-FF-3306
|
2
|
LUSC (2)
|
92.1 | 319.8 | 8.1E-98 | 237 |
| 1.25.10.20 | Microsomal triglyceride transfer protein
1.25.10.20-FF-1443
|
2
|
SKCM (2)
|
90.5 | 121.7 | 1.4E-36 | 794 |
| 1.25.40.70 | Phosphatidylinositol 3-kinase gamma isoform
1.25.40.70-FF-2223
|
970
|
STAD (44)
BLCA (106)
COAD (84)
UCEC (116)
ESCA (12)
BRCA (212)
CESC (128)
HNSC (98)
KIRP (8)
LUSC (66)
TGCT (4)
UCS (14)
LUAD (24)
LGG (12)
SKCM (10)
READ (4)
GBM (14)
LIHC (4)
PRAD (6)
KIRC (2)
CHOL (2)
|
92.3 | 106.5 | 6.2E-32 | 1101 |
| 2.10.50.10 | TNF receptor superfamily, member 1A
2.10.50.10-FF-7632
|
4
|
UCEC (4)
|
82.2 | 101.1 | 6.8E-32 | 45 |
| 3.10.20.90 | Transcription elongation factor B polypeptide 2
3.10.20.90-FF-1161
|
2
|
UCEC (2)
|
84.9 | 168.8 | 5.3E-53 | 122 |
| 3.10.20.90 | Phosphoinositide phospholipase C
3.10.20.90-FF-15929
|
10
|
SKCM (2)
DLBC (2)
LGG (2)
STAD (2)
COAD (2)
|
76.8 | 152.2 | 3.1E-47 | 131 |
| 3.10.20.90 | Plexin A4 isoform 1
3.10.20.90-FF-15968
|
2
|
UCEC (2)
|
72.1 | 169.4 | 2.7E-53 | 419 |
| 3.30.1370.10 | RNA-binding E3 ubiquitin-protein ligase MEX3C
3.30.1370.10-FF-8205
|
8
|
UCEC (6)
COAD (2)
|
82.6 | 118.9 | 8.7E-37 | 438 |