| Superfamily | Functional Family | Mutation Events | Mutation Types | DOPS | Incl. Bitscore | Incl. Evalue | Seqs |
|---|---|---|---|---|---|---|---|
| 3.40.910.10 | Probable deoxyhypusine synthase 1
3.40.910.10-FF-602
|
10
|
UCEC (8)
STAD (2)
|
88.6 | 243.2 | 2.1E-73 | 1553 |
| 3.40.50.10190 | PAX-interacting protein 1
3.40.50.10190-FF-8685
|
2
|
LUSC (2)
|
83.4 | 164.8 | 3.1E-51 | 118 |
| 3.40.50.10190 | DNA topoisomerase 2-binding protein 1
3.40.50.10190-FF-8728
|
2
|
BRCA (2)
|
71.1 | 183.8 | 2.1E-57 | 80 |
| 3.40.50.10190 | DNA topoisomerase 2-binding protein 1
3.40.50.10190-FF-8827
|
4
|
BLCA (2)
CESC (2)
|
76.2 | 162.7 | 7.9E-51 | 80 |
| 3.40.50.10190 | Protein ECT2
3.40.50.10190-FF-6404
|
6
|
UCEC (2)
LUSC (2)
READ (2)
|
82.8 | 121.1 | 9.6E-38 | 94 |
| 1.10.287.80 | Lysine-specific histone demethylase 1A
1.10.287.80-FF-3084
|
6
|
UCEC (4)
BLCA (2)
|
97.8 | 102.2 | 1.8E-31 | 221 |
| 3.40.50.2020 | Phosphoribosyltransferase domain-containing protein 1
3.40.50.2020-FF-18395
|
2
|
UCEC (2)
|
86.9 | 253.7 | 1.8E-77 | 733 |
| 3.40.50.2020 | Adenine phosphoribosyltransferase, isoform C
3.40.50.2020-FF-18599
|
12
|
SKCM (2)
STAD (2)
BLCA (2)
CESC (2)
LUSC (2)
UCEC (2)
|
91.3 | 171.0 | 2.0E-52 | 627 |
| 3.90.180.10 | Quinone oxidoreductase Qor
3.90.180.10-FF-34016
|
2
|
SKCM (2)
|
93.0 | 128.2 | 1.1E-39 | 622 |
| 3.90.180.10 | Quinone oxidoreductase isoform a
3.90.180.10-FF-34032
|
6
|
SKCM (4)
STAD (2)
|
89.9 | 150.6 | 1.6E-46 | 134 |
| 1.20.900.10 | Son of sevenless 1
1.20.900.10-FF-3285
|
24
|
LUSC (4)
UCEC (12)
LUAD (8)
|
88.0 | 280.2 | 1.3E-85 | 218 |
| 1.20.900.10 | Rho guanine nucleotide exchange factor 7
1.20.900.10-FF-3298
|
6
|
UCEC (4)
COAD (2)
|
91.3 | 296.2 | 1.4E-90 | 288 |
| 1.20.900.10 | FERM, RhoGEF and pleckstrin domain-containing protein 1
1.20.900.10-FF-3306
|
2
|
LUSC (2)
|
92.1 | 319.8 | 8.1E-98 | 237 |
| 1.25.10.20 | Microsomal triglyceride transfer protein
1.25.10.20-FF-1443
|
2
|
SKCM (2)
|
90.5 | 121.7 | 1.4E-36 | 794 |
| 1.25.40.70 | Phosphatidylinositol 3-kinase gamma isoform
1.25.40.70-FF-2223
|
970
|
STAD (44)
BLCA (106)
COAD (84)
UCEC (116)
ESCA (12)
BRCA (212)
CESC (128)
HNSC (98)
KIRP (8)
LUSC (66)
TGCT (4)
UCS (14)
LUAD (24)
LGG (12)
SKCM (10)
READ (4)
GBM (14)
LIHC (4)
PRAD (6)
KIRC (2)
CHOL (2)
|
92.3 | 106.5 | 6.2E-32 | 1101 |
| 2.10.50.10 | TNF receptor superfamily, member 1A
2.10.50.10-FF-7632
|
4
|
UCEC (4)
|
82.2 | 101.1 | 6.8E-32 | 45 |
| 3.10.20.90 | Phosphoinositide phospholipase C
3.10.20.90-FF-15929
|
10
|
SKCM (2)
DLBC (2)
LGG (2)
STAD (2)
COAD (2)
|
76.8 | 152.2 | 3.1E-47 | 131 |
| 3.10.20.90 | Plexin A4 isoform 1
3.10.20.90-FF-15968
|
2
|
UCEC (2)
|
72.1 | 169.4 | 2.7E-53 | 419 |
| 3.10.20.90 | Transcription elongation factor B polypeptide 2
3.10.20.90-FF-1161
|
2
|
UCEC (2)
|
84.9 | 168.8 | 5.3E-53 | 122 |
| 3.30.1370.10 | RNA-binding E3 ubiquitin-protein ligase MEX3C
3.30.1370.10-FF-8205
|
8
|
UCEC (6)
COAD (2)
|
82.6 | 118.9 | 8.7E-37 | 438 |