| Superfamily | Functional Family | Mutation Events | Mutation Types | DOPS | Incl. Bitscore | Incl. Evalue | Seqs |
|---|---|---|---|---|---|---|---|
| 3.30.505.10 | SH3 domain-binding protein 2
3.30.505.10-FF-2646
|
12
|
GBM (2)
UCEC (6)
KIRC (2)
SKCM (2)
|
72.0 | 177.7 | 1.6E-55 | 74 |
| 3.30.505.10 | Tyrosine-protein kinase SYK isoform 1
3.30.505.10-FF-4136
|
4
|
SKCM (2)
UCEC (2)
|
84.4 | 166.5 | 1.0E-51 | 123 |
| 3.30.505.10 | Tyrosine-protein kinase Fer
3.30.505.10-FF-4210
|
4
|
SKCM (2)
COAD (2)
|
76.0 | 192.8 | 8.0E-60 | 200 |
| 3.40.50.261 | ATP-citrate synthase subunit 1
3.40.50.261-FF-4818
|
2
|
PAAD (2)
|
85.9 | 229.9 | 7.3E-70 | 1203 |
| 3.30.505.10 | Proto-oncogene tyrosine-protein kinase Src
3.30.505.10-FF-4228
|
6
|
ESCA (2)
SKCM (4)
|
93.1 | 113.2 | 2.7E-34 | 1205 |
| 3.30.505.10 | E3 ubiquitin-protein ligase CBL
3.30.505.10-FF-4233
|
14
|
READ (2)
UCEC (8)
COAD (2)
STAD (2)
|
88.6 | 137.9 | 1.3E-42 | 548 |
| 3.30.505.10 | Signal transducer and activator of transcription
3.30.505.10-FF-4254
|
2
|
UCEC (2)
|
80.1 | 132.6 | 1.5E-40 | 533 |
| 3.30.505.10 | Non-specific protein-tyrosine kinase
3.30.505.10-FF-4276
|
2
|
SKCM (2)
|
92.7 | 135.8 | 1.5E-41 | 637 |
| 3.30.505.10 | Phosphoinositide phospholipase C
3.30.505.10-FF-4278
|
14
|
READ (2)
UCEC (4)
CESC (4)
SKCM (2)
STAD (2)
|
91.7 | 142.2 | 6.4E-44 | 380 |
| 3.30.505.10 | Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1
3.30.505.10-FF-4288
|
4
|
UCEC (2)
STAD (2)
|
85.4 | 106.9 | 6.9E-33 | 465 |
| 3.30.505.10 | Cytokine-dependent hematopoietic cell linker
3.30.505.10-FF-4294
|
6
|
LUSC (2)
CESC (2)
UCEC (2)
|
93.2 | 160.4 | 1.1E-49 | 164 |
| 3.40.390.10 | Disintegrin and metalloproteinase domain-containing protein 22
3.40.390.10-FF-13199
|
2
|
SKCM (2)
|
86.4 | 194.5 | 3.0E-59 | 332 |
| 3.40.50.10470 | Putative methylthioribose-1-phosphate isomerase protein
3.40.50.10470-FF-1910
|
2
|
HNSC (2)
|
90.5 | 192.1 | 8.5E-58 | 1443 |
| 3.40.50.261 | Succinyl-CoA ligase [ADP-forming] subunit alpha
3.40.50.261-FF-4912
|
2
|
UCEC (2)
|
88.7 | 211.9 | 9.0E-64 | 3590 |
| 3.40.50.261 | Succinyl-CoA ligase subunit beta
3.40.50.261-FF-4924
|
4
|
COAD (2)
UCEC (2)
|
98.2 | 127.1 | 1.2E-37 | 3364 |
| 1.10.510.10 | Casein kinase II subunit alpha
1.10.510.10-FF-26544
|
18
|
COAD (4)
UCEC (6)
BLCA (2)
SKCM (2)
KIRP (2)
CESC (2)
|
84.2 | 241.4 | 3.0E-74 | 2712 |
| 3.90.79.10 | Diphosphoinositol polyphosphate phosphohydrolase 1
3.90.79.10-FF-21430
|
12
|
SKCM (2)
LUSC (2)
UCEC (6)
STAD (2)
|
70.3 | 216.9 | 7.1E-67 | 1082 |
| 3.90.79.10 | ADP-ribose pyrophosphatase, mitochondrial
3.90.79.10-FF-21597
|
2
|
ACC (2)
|
94.5 | 157.0 | 2.7E-48 | 152 |
| 1.10.510.10 | Fibroblast growth factor receptor 1
1.10.510.10-FF-21492
|
10
|
BLCA (4)
GBM (4)
KIRP (2)
|
79.3 | 257.9 | 1.9E-80 | 659 |
| 1.10.510.10 | RAC-beta serine/threonine-protein kinase
1.10.510.10-FF-78056
|
16
|
KIRC (4)
UCEC (4)
LUAD (2)
CESC (2)
LIHC (2)
PRAD (2)
|
93.1 | 200.5 | 8.4E-62 | 1516 |