| Superfamily | Functional Family | Mutation Events | Mutation Types | DOPS | Incl. Bitscore | Incl. Evalue | Seqs |
|---|---|---|---|---|---|---|---|
| 2.60.40.790 | Prostaglandin E synthase 3
2.60.40.790-FF-7583
|
2
|
UCEC (2)
|
79.6 | 225.3 | 7.2E-70 | 633 |
| 2.60.40.790 | Alpha-crystallin B chain
2.60.40.790-FF-7693
|
4
|
UCEC (2)
COAD (2)
|
95.2 | 128.6 | 1.8E-39 | 613 |
| 2.80.10.50 | Fibroblast growth factor 9
2.80.10.50-FF-13030
|
2
|
SKCM (2)
|
90.3 | 201.4 | 5.5E-62 | 1667 |
| 2.80.10.50 | Fibroblast growth factor 7
2.80.10.50-FF-13074
|
6
|
SKCM (4)
GBM (2)
|
84.6 | 182.8 | 1.2E-56 | 784 |
| 2.80.10.50 | Fibroblast growth factor 10
2.80.10.50-FF-13108
|
2
|
SKCM (2)
|
92.4 | 175.5 | 4.5E-54 | 153 |
| 3.10.450.10 | Latexin
3.10.450.10-FF-2095
|
4
|
UCEC (2)
LGG (2)
|
73.8 | 198.7 | 5.8E-62 | 38 |
| 2.80.10.50 | Fascin
2.80.10.50-FF-13130
|
8
|
CESC (2)
SKCM (2)
COAD (2)
KIRC (2)
|
94.2 | 189.7 | 1.2E-58 | 150 |
| 3.10.450.10 | Cystatin-B
3.10.450.10-FF-2148
|
6
|
BLCA (2)
LIHC (2)
CESC (2)
|
94.1 | 152.1 | 1.1E-47 | 101 |
| 2.80.10.50 | Fibroblast growth factor 2
2.80.10.50-FF-13155
|
2
|
COAD (2)
|
95.1 | 169.8 | 2.4E-52 | 303 |
| 2.80.10.50 | Fibroblast growth factor 23
2.80.10.50-FF-13204
|
20
|
HNSC (2)
SKCM (4)
UCEC (6)
COAD (2)
PRAD (2)
LUAD (2)
STAD (2)
|
93.1 | 183.7 | 7.6E-57 | 88 |
| 2.80.10.50 | Polypeptide N-acetylgalactosaminyltransferase 13
2.80.10.50-FF-13281
|
8
|
COAD (4)
LUAD (4)
|
97.9 | 104.4 | 2.2E-32 | 242 |
| 2.60.120.470 | Thioredoxin-like 1 variant
2.60.120.470-FF-311
|
16
|
READ (2)
UCEC (12)
COAD (2)
|
97.1 | 124.5 | 3.8E-38 | 334 |
| 3.50.50.60 | Dihydrolipoyl dehydrogenase, mitochondrial
3.50.50.60-FF-112529
|
10
|
STAD (2)
KIRP (2)
LUAD (2)
LUSC (4)
|
79.0 | 253.6 | 1.6E-77 | 165 |
| 1.10.800.10 | Aromatic amino acid hydroxylase 1
1.10.800.10-FF-550
|
6
|
SKCM (6)
|
83.6 | 332.8 | 1.0E-100 | 1032 |
| 1.20.5.270 | Cytochrome b-c1 complex subunit Rieske, mitochondrial
1.20.5.270-FF-198
|
2
|
UCEC (2)
|
86.0 | 116.8 | 2.1E-36 | 182 |
| 3.50.50.60 | Dihydrolipoyl dehydrogenase, mitochondrial
3.50.50.60-FF-78468
|
8
|
LUAD (2)
STAD (2)
PRAD (2)
UCEC (2)
|
75.6 | 185.2 | 4.5E-59 | 214 |
| 3.20.20.140 | AMP deaminase, isoform K
3.20.20.140-FF-39821
|
8
|
UCEC (6)
COAD (2)
|
83.8 | 185.3 | 7.1E-56 | 1232 |
| 2.60.40.720 | Cellular tumor antigen p53
2.60.40.720-FF-7
|
2284
|
STAD (138)
UCEC (140)
BLCA (158)
BRCA (156)
COAD (158)
GBM (100)
HNSC (226)
KICH (8)
LGG (268)
LUAD (152)
LUSC (250)
MESO (14)
OV (34)
PAAD (64)
READ (68)
UCS (44)
ACC (6)
CESC (12)
ESCA (116)
LIHC (58)
SARC (42)
CHOL (2)
KIRC (4)
PRAD (44)
SKCM (12)
PCPG (2)
THYM (4)
DLBC (4)
|
91.9 | 114.4 | 1.8E-35 | 201 |
| 2.60.40.720 | Cellular tumor antigen p53
2.60.40.720-FF-232
|
12
|
SKCM (2)
BLCA (4)
CESC (2)
COAD (2)
UCEC (2)
|
84.7 | 223.5 | 3.8E-68 | 443 |
| 3.20.20.140 | Putative D-hydantoinase (Dihydropyrimidinase)
3.20.20.140-FF-40287
|
2
|
SKCM (2)
|
92.0 | 256.0 | 5.7E-77 | 1750 |