| Superfamily | Functional Family | Mutation Events | Mutation Types | DOPS | Incl. Bitscore | Incl. Evalue | Seqs |
|---|---|---|---|---|---|---|---|
| 2.60.120.590 | Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3
2.60.120.590-FF-2394
|
2
|
LIHC (2)
|
92.7 | 292.6 | 7.8E-90 | 122 |
| 2.60.40.790 | Alpha-crystallin B chain
2.60.40.790-FF-7693
|
4
|
UCEC (2)
COAD (2)
|
95.2 | 128.6 | 1.8E-39 | 613 |
| 2.80.10.50 | Fibroblast growth factor 9
2.80.10.50-FF-13030
|
2
|
SKCM (2)
|
90.3 | 201.4 | 5.5E-62 | 1667 |
| 2.80.10.50 | Fibroblast growth factor 7
2.80.10.50-FF-13074
|
6
|
SKCM (4)
GBM (2)
|
84.6 | 182.8 | 1.2E-56 | 784 |
| 2.80.10.50 | Fibroblast growth factor 10
2.80.10.50-FF-13108
|
2
|
SKCM (2)
|
92.4 | 175.5 | 4.5E-54 | 153 |
| 2.80.10.50 | Fascin
2.80.10.50-FF-13130
|
8
|
CESC (2)
SKCM (2)
COAD (2)
KIRC (2)
|
94.2 | 189.7 | 1.2E-58 | 150 |
| 3.10.450.10 | Latexin
3.10.450.10-FF-2095
|
4
|
UCEC (2)
LGG (2)
|
73.8 | 198.7 | 5.8E-62 | 38 |
| 2.80.10.50 | Fibroblast growth factor 2
2.80.10.50-FF-13155
|
2
|
COAD (2)
|
95.1 | 169.8 | 2.4E-52 | 303 |
| 2.80.10.50 | Fibroblast growth factor 23
2.80.10.50-FF-13204
|
20
|
HNSC (2)
SKCM (4)
UCEC (6)
COAD (2)
PRAD (2)
LUAD (2)
STAD (2)
|
93.1 | 183.7 | 7.6E-57 | 88 |
| 3.10.450.10 | Cystatin-B
3.10.450.10-FF-2148
|
6
|
BLCA (2)
LIHC (2)
CESC (2)
|
94.1 | 152.1 | 1.1E-47 | 101 |
| 2.80.10.50 | Polypeptide N-acetylgalactosaminyltransferase 13
2.80.10.50-FF-13281
|
8
|
COAD (4)
LUAD (4)
|
97.9 | 104.4 | 2.2E-32 | 242 |
| 3.50.50.60 | Dihydrolipoyl dehydrogenase, mitochondrial
3.50.50.60-FF-112529
|
10
|
STAD (2)
KIRP (2)
LUAD (2)
LUSC (4)
|
79.0 | 253.6 | 1.6E-77 | 165 |
| 3.50.50.60 | Dihydrolipoyl dehydrogenase, mitochondrial
3.50.50.60-FF-78468
|
8
|
LUAD (2)
STAD (2)
PRAD (2)
UCEC (2)
|
75.6 | 185.2 | 4.5E-59 | 214 |
| 3.20.20.140 | AMP deaminase, isoform K
3.20.20.140-FF-39821
|
8
|
UCEC (6)
COAD (2)
|
83.8 | 185.3 | 7.1E-56 | 1232 |
| 1.10.800.10 | Aromatic amino acid hydroxylase 1
1.10.800.10-FF-550
|
6
|
SKCM (6)
|
83.6 | 332.8 | 1.0E-100 | 1032 |
| 1.20.5.270 | Cytochrome b-c1 complex subunit Rieske, mitochondrial
1.20.5.270-FF-198
|
2
|
UCEC (2)
|
86.0 | 116.8 | 2.1E-36 | 182 |
| 2.60.40.720 | Cellular tumor antigen p53
2.60.40.720-FF-7
|
2284
|
STAD (138)
UCEC (140)
BLCA (158)
BRCA (156)
COAD (158)
GBM (100)
HNSC (226)
KICH (8)
LGG (268)
LUAD (152)
LUSC (250)
MESO (14)
OV (34)
PAAD (64)
READ (68)
UCS (44)
ACC (6)
CESC (12)
ESCA (116)
LIHC (58)
SARC (42)
CHOL (2)
KIRC (4)
PRAD (44)
SKCM (12)
PCPG (2)
THYM (4)
DLBC (4)
|
91.9 | 114.4 | 1.8E-35 | 201 |
| 2.60.120.470 | Thioredoxin-like 1 variant
2.60.120.470-FF-311
|
16
|
READ (2)
UCEC (12)
COAD (2)
|
97.1 | 124.5 | 3.8E-38 | 334 |
| 3.20.20.140 | Putative D-hydantoinase (Dihydropyrimidinase)
3.20.20.140-FF-40287
|
2
|
SKCM (2)
|
92.0 | 256.0 | 5.7E-77 | 1750 |
| 2.60.40.720 | Cellular tumor antigen p53
2.60.40.720-FF-232
|
12
|
SKCM (2)
BLCA (4)
CESC (2)
COAD (2)
UCEC (2)
|
84.7 | 223.5 | 3.8E-68 | 443 |