| Superfamily | Functional Family | Mutation Events | Mutation Types | DOPS | Incl. Bitscore | Incl. Evalue | Seqs |
|---|---|---|---|---|---|---|---|
| 2.60.120.260 | DNA repair protein XRCC1
2.60.120.260-FF-35189
|
2
|
LUSC (2)
|
84.5 | 222.9 | 5.1E-69 | 71 |
| 3.40.630.30 | Alpha-tubulin N-acetyltransferase 1
3.40.630.30-FF-70368
|
2
|
UCEC (2)
|
88.5 | 265.9 | 9.2E-83 | 116 |
| 3.40.630.30 | N(Alpha)-acetyltransferase 50, NatE catalytic subunit
3.40.630.30-FF-70410
|
6
|
PRAD (2)
LUSC (2)
STAD (2)
|
97.8 | 179.4 | 3.2E-55 | 950 |
| 3.90.226.10 | Acetyl-CoA carboxylase 2
3.90.226.10-FF-34021
|
6
|
SKCM (2)
COAD (2)
BRCA (2)
|
89.6 | 216.1 | 2.2E-66 | 797 |
| 3.90.226.10 | Enoyl-CoA hydratase/isomerase family, putative
3.90.226.10-FF-34054
|
14
|
SKCM (2)
UCEC (6)
STAD (2)
COAD (2)
LUSC (2)
|
85.3 | 220.3 | 4.0E-67 | 1259 |
| 3.40.50.10590 | Probable aminopeptidase NPEPL1
3.40.50.10590-FF-47
|
4
|
CESC (2)
BLCA (2)
|
91.6 | 181.1 | 3.4E-56 | 52 |
| 3.90.70.10 | Ubl carboxyl-terminal hydrolase 18
3.90.70.10-FF-16776
|
10
|
BLCA (2)
UCEC (2)
COAD (2)
SARC (2)
SKCM (2)
|
74.1 | 590.1 | 1.6E-180 | 41 |
| 3.90.70.10 | Aminopeptidase C (Bleomycin hydrolase)
3.90.70.10-FF-16963
|
2
|
UCEC (2)
|
87.3 | 367.0 | 6.0E-111 | 3058 |
| 3.90.70.10 | Cathepsin B-like cysteine protease
3.90.70.10-FF-17146
|
12
|
SKCM (4)
UCEC (4)
STAD (2)
CESC (2)
|
83.7 | 141.2 | 4.3E-42 | 1011 |
| 1.10.1300.10 | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A
1.10.1300.10-FF-1247
|
14
|
UCEC (8)
LUSC (2)
ACC (2)
COAD (2)
|
84.5 | 494.3 | 9.9E-151 | 178 |
| 1.20.1200.10 | Cob(I)yrinic acid a,c-diamide adenosyltransferase
1.20.1200.10-FF-1240
|
4
|
UCEC (2)
HNSC (2)
|
90.7 | 176.8 | 2.5E-54 | 314 |
| 2.60.210.10 | Speckle-type POZ protein B
2.60.210.10-FF-909
|
106
|
PRAD (74)
UCEC (18)
LUSC (4)
DLBC (2)
LGG (2)
ESCA (2)
BLCA (2)
ACC (2)
|
97.9 | 145.6 | 6.2E-45 | 1444 |
| 2.60.370.10 | Cytochrome c oxidase assembly protein
2.60.370.10-FF-342
|
4
|
LIHC (2)
UCEC (2)
|
84.9 | 103.6 | 5.7E-31 | 1785 |
| 3.10.450.50 | NTF2-related export protein 2
3.10.450.50-FF-22898
|
4
|
SKCM (2)
COAD (2)
|
88.8 | 216.9 | 7.8E-67 | 240 |
| 3.10.450.50 | Calcium/calmodulin-dependent protein kinase II
3.10.450.50-FF-23047
|
2
|
KIRP (2)
|
87.8 | 132.8 | 2.2E-40 | 1314 |
| 3.30.9.10 | D-amino-acid oxidase, isoform CRA_a
3.30.9.10-FF-17650
|
2
|
LUAD (2)
|
77.3 | 188.1 | 1.3E-58 | 46 |
| 3.40.50.150 | Guanidinoacetate N-methyltransferase
3.40.50.150-FF-131210
|
4
|
SKCM (4)
|
79.3 | 375.4 | 2.8E-115 | 80 |
| 3.40.50.150 | Protein arginine N-methyltransferase 5
3.40.50.150-FF-135349
|
10
|
SKCM (8)
LUAD (2)
|
86.9 | 230.8 | 1.1E-70 | 424 |
| 3.40.50.150 | AlkB, alkylation repair homolog 8
3.40.50.150-FF-135844
|
2
|
LUAD (2)
|
83.8 | 116.4 | 4.1E-35 | 1246 |
| 3.40.50.150 | Chromosome 1 open reading frame 59
3.40.50.150-FF-135913
|
2
|
UCEC (2)
|
85.2 | 274.6 | 3.4E-84 | 104 |